Why does tissue function decline in ageing? One reason is that the stem cells that maintain normal homeostasis become mis-regulated. In our latest preprint, we identify the transcription factor Sob as a key regulator of Drosophila intestinal stem cells and aging. www.biorxiv.org/content/10.6...
The Transcription Factor Sob Maintains Intestinal Stem Cell Homeostasis to Delay Ageing
Ageing is associated with physiological decline and disrupted tissue homeostasis, often driven by imbalanced stem cell activity. The Drosophila midgut serves as a powerful model for studying epithelia...
biorxiv.org