D. Ross Camidge

@drcamidge.bsky.social

Oncologist, writer, award-winning ‘How This is Building Me’ Onclive podcast host - fan of truth, creativity and humor https://podcasts.apple.com/us/podcast/how-this-is-building-me/id1726421043

It was a wild week. I knew I had the pleural effusion building up but on Friday I developed this right flank pain. I controlled it with simple analgesics but by Sunday it was making me vomit. Short story- I had right ureteric compression. My right kidney was swelling like tom and Jerry’s hosepipe

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The difference between the left and right is 10 days and 1.7 liters drained from my right lung. They don’t look different (my right is on the left as you look) because the fluid built up again quickly. I’m fine at rest but changing position makes me cough. Plan is a more permanent drain due soon.

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The best explanation of these observations is that a new deposit, potentially of any cancer in the brain, requires resistance to whatever systemic therapy is ongoing AND NTRK-BDNF interactions. Block either and no new brain mets thttps://www.sciencedirect.com/science/article/pii/S1556086426001802

sciencedirect.com

To mark Father’s Day I learned how to make jewelry and today gave each of my daughters a sterling silver ring I’d made for them. Then we had dinner and watched Toy Story 5 at the movies. Simple pleasures, shared time.

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The very talented Lisa Goldman sent me this watercolor earlier this year. She chose a poppy as they grow in disturbed ground and are beautiful. The sentiment is true for all of us, a diagnosis of cancer might emphasize this but it doesn’t own this thought

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A tale of two tkis. Lorlatinib prevents new brain Mets. Based on intracranial Duration of Response neladalkib (admittedly in later line) doesn’t show the same flat line. Anti-ntrk’s cns protective effect separate from driver oncogene status is writ large. Still hiding in plain sight

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Coming to the end of my family and work trip. Started with scattering my mum’s ashes at Crail in Scotland with my brother and ended with visiting my dad’s grave in Teddington, Greater London. Good goodbyes.

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Grand Rounds at the John Radcliffe Hospital, Oxford. Last time I was here I was a junior doctor from the Oxford University Medical School. This time I could tell a 16 year lung cancer survivor’s story and in the process change hearts and minds about what it means to live with this disease.

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