I'm excited to share my postdoc work where we characterized the #Legionella effector SidL, finding that it modifies a host #glycolysis metabolite to produce a novel molecule that is incompatible with host #metabolism and uncovers a new mode in which pathogens can manipulate their host environment.

Green Lab JHMI@greenlab.bsky.social · 3w ago

Wait, what?! This isn’t about ribosomes? Check out our new work where we find that a #Legionella effector thought to target host translation instead targets metabolism by modifying a host glycolytic metabolite. Led by @drjoshblack.bsky.social www.cell.com/molecular-ce...