Steven Cook
@dumpyunc.bsky.social
Member of Technical Staff @ Flourish Former worm neuron counter
Our Method of the Year 2025 is...drumroll please...EM-based connectomics!! Our Editorial introduces our choice and highlights six Comments and other related content in this special issue. Please join us in celebrating EM-based connectomics! 🎉🧠🔬 www.nature.com/articles/s41...
Method of the Year 2025: electron microscopy-based connectomics - Nature Methods
A large network of interconnected neurons serves as the basis of brain function and of behavior. Methodological advances have enabled the reconstruction of large-scale and even whole-brain connectomes...
nature.com
Stop by MM15 and adjacent posters to see our posters on connectomics approaches using electron and light microscopy! #sfn25
If it’s your dream job to map the brain using light microscopy we should talk at #sfn25. Multiple opportunities. DMs open.
The connectome of the entire male Drosophila central nervous system is out!! Acquired using FIB-SEM @ 8x8x8nm, we aligned 7.5 mio 2D images aligned into one seamless 3D volume, which was used to segment & proofread neurons and synapses. @hhmijanelia.bsky.social www.biorxiv.org/content/10.1...
Our group at the Allen Institute is recruiting a technician and postdoc to work on light microscopy-based connectomics. Please DM me or share with anyone you think may be interested in this NIH BRAIN CONNECTS funded project.
E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves. Read more: e11.bio/blog/prism
Synaptic connectomics: status and prospects — a Comment article by Davi D. Bock @dddavi.bsky.social #neuroscience #neuroskyence www.nature.com/articles/s41...
Synaptic connectomics: status and prospects - Nature Reviews Neuroscience
High-throughput volume electron microscopy and deep learning-driven automated segmentation have revolutionized the mapping of neural circuits at the level of individual neurons and synapses, revealing...
nature.com
With @megyounger.bsky.social's lab, et al., we present the first connectomics work in the disease-vector mosquito Aedes aegypti, revealing how its brain is wired to detect host cues. Preprint: doi.org/10.1101/2025... #Neuroscience #Connectomics #vEM #VectorBiology 🧪
Meg Younger@megyounger.bsky.social · last yr.New preprint from @darbly.bsky.social @briandepasquale.bsky.social and my labs! If you love (or hate) mosquitoes, have a look: doi.org/10.1101/2025... We used TEM to describe the circuitry used for CO2 detection by mosquitoes. As usual with mosquitoes, nothing is as expected! 🌬️🦟
How is the nervous system organized to coordinate behavior? To approach this massive question, a team led by @asbates.bsky.social, @jasper-tms.bsky.social, @mindyisminsu.bsky.social, & Helen Yang present the BANC: a Brain and Nerve Cord connectome. Preprint: doi.org/10.1101/2025... 🧪#Neuroskyence
Alexander Shakeel Bates@asbates.bsky.social · last yr.Public access to the first fly connectome that spans the whole CNS - BANC!: codex.flywire.ai?dataset=banc Different from prior connectomes - it is brain + cord (think spinal cord) We use it to ‘embody’ the system and find it resembles ‘subsumption architecture’ doi.org/10.1101/2025...
Happy to share our publication - Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution www.science.org/doi/10.1126/...
Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution
Understanding the evolution of the bilaterian brain requires a detailed exploration of the precise nature of cellular and subcellular differences between related species. We undertook an electron micr...
science.org
I may not be at #worm25 but the real discussion endures
Michael Hendricks 🇨🇦@michaelhendricks.bsky.social · last yr.The number of C. elegans neurons must always be contested, unknowable, liminal in order to maintain humility in our efforts to list, label, and categorize nature, which is indifferent to our schemas.
First bird of 2025: yellow-rumped warbler on the suet feeder
Winter break’s challenge: organize and rebuild my LEGO sets from the early 90s
We're looking for an Allen Institute summer intern interested in mapping single neuron projectomes/proteomes in the human brain! Happy to chat with anyone about the opportunity and please share with anyone you think may be interested. alleninstitute.org/careers/inte...
Internship & Postbaccalaureate Programs
Students and early-career professionals in lab research, biology, neuroscience, immunology, and others should apply for our internships and fellowships.
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