DZNE research center

@dzne.science

Dedicated to advancing the scientific understanding of neurodegenerative diseases - from mechanisms to diagnosis, therapy, and prevention (such as AD, PD or ALS). đź”— Imprint: https://dzne.de/en/imprint đź”— Data Protection: https://dzne.de/en/data-protection/

New paper out: All-optical closed-loop control of human cardiomyocyte networks exploiting holographic optogenetics.: Wendland, Robert; Schmieder, Felix; Sikandar, Muhammad Atif; et al. Communications engineering Vol. 5, no. 1, p. 159 | Thanks for sharing #dzne #papers

All-optical closed-loop control of human cardiomyocyte networks exploiting holographic optogenetics.

Wendland, Robert; Schmieder, Felix; Sikandar, Muhammad Atif; et al. Communications engineering Vol. 5, no. 1, p. 159

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New paper out: 4-Repeat Tauopathien – Progressive Supranukleäre Blickparese und kortikobasale Degeneration | 4-Repeat Tauopathies: Progressive Supranuclear Palsy andCorticobasal Degeneration: Palleis, Carla Teresa; Bernhardt, Alexander; Höglinger, Günter… | Thanks for sharing #dzne #papers

4-Repeat Tauopathien – Progressive Supranukleäre Blickparese und kortikobasale Degeneration | 4-Repeat Tauopathies: Progressive Supranuclear Palsy andCorticobasal Degeneration

Palleis, Carla Teresa; Bernhardt, Alexander; Höglinger, Günter Fortschritte der Neurologie, Psychiatrie Vol. 94, no. 9, p. 389 - 399

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New paper out: Neuroradiologic Findings in Patients With SCN2A Disease: A Systematic Review and Retrospective Multicenter Cohort Study.: Bamborschke, Daniel; Bendella, Zeynep; Allen, Meagan; et al. Neurology Vol. 107, no. 7, p. e218541 | Thanks for sharing #dzne #papers

Neuroradiologic Findings in Patients With SCN2A Disease: A Systematic Review and Retrospective Multicenter Cohort Study.

Bamborschke, Daniel; Bendella, Zeynep; Allen, Meagan; et al. Neurology Vol. 107, no. 7, p. e218541

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How do neurons grow during their early stages of development? And how can these processes be reactivated so that damaged neurons can regenerate? Don’t miss Frank Bradke, Professor at the DZNE Bonn @dzne.science, at our next keynote lecture! 📅 September 29 at 11:00 a.m. 📍 Room NQ105, Martinsried

Poster announcing a keynote lecture by Frank Bradke. The poster's background features a stylized, single-color illustration of a neuron with branching axons and circular nodes.

New paper out: Association of oral anticoagulation persistence and health-related quality of life in stroke survivors with atrial fibrillation: long-term results of the Berlin atrial fibrillation registry.: Steindorf-Sabath, Lena; Olma, Manuel C; Tütüncü, Serdar;… | Thanks for sharing #dzne #papers

Association of oral anticoagulation persistence and health-related quality of life in stroke survivors with atrial fibrillation: long-term results of the Berlin atrial fibrillation registry.

Steindorf-Sabath, Lena; Olma, Manuel C; Tütüncü, Serdar; et al. Neurological research and practice Vol. 8, no. 1, p. 78

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New paper out: Inconsistent subthalamic local field potential beta activity amid in- and antiphasic neuronal bursts.: Scherer, Maximilian; Wiedemann, Nina; Bötzel, Kai; et al. npj Parkinson's Disease Vol. 12, no. 1, p. 222 | Thanks for sharing #dzne #papers

Inconsistent subthalamic local field potential beta activity amid in- and antiphasic neuronal bursts.

Scherer, Maximilian; Wiedemann, Nina; Bötzel, Kai; et al. npj Parkinson's Disease Vol. 12, no. 1, p. 222

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New paper out: Associations of physical fitness with brain structure, pathology and cognition in cognitively normal older adults.: Schwarck, Svenja; Behrenbruch, Niklas; Schumann-Werner, Beate; et al. npj aging Vol. 12, no. 1, p. 129 | Thanks for sharing #dzne #papers

Associations of physical fitness with brain structure, pathology and cognition in cognitively normal older adults.

Schwarck, Svenja; Behrenbruch, Niklas; Schumann-Werner, Beate; et al. npj aging Vol. 12, no. 1, p. 129

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New paper out: Structural Brain Changes Are Linked to Clinical and Cognitive Outcomes in Anti-LGI1 Encephalitis.: Zhao, Wei; Wurdack, Katharina; Bartels, Frederik; et al. Neurology: Neuroimmunology & Neuroinflammation ; official journal of the American Academy of… | Thanks for sharing #dzne #papers

Structural Brain Changes Are Linked to Clinical and Cognitive Outcomes in Anti-LGI1 Encephalitis.

Zhao, Wei; Wurdack, Katharina; Bartels, Frederik; et al. Neurology: Neuroimmunology & Neuroinflammation ; official journal of the American Academy of Neurology Vol. 13, no. 6, p. e200649

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New paper out: Individualized antisense oligonucleotide treatment eligibility of patients living with neurodevelopmental diseases.: Aartsma-Rus, Annemieke; de Gusmao, Claudio Melo; Demarest, Scott; et al. Cell reports / Medicine Vol. 7, no. 9, p. 102989 - | Thanks for sharing #dzne #papers

Individualized antisense oligonucleotide treatment eligibility of patients living with neurodevelopmental diseases.

Aartsma-Rus, Annemieke; de Gusmao, Claudio Melo; Demarest, Scott; et al. Cell reports / Medicine Vol. 7, no. 9, p. 102989 -

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New paper out: Functional network reorganization after magnetic resonance-guided focused ultrasound thalamotomy in tremor-dominant Parkinson's disease patients.: Liu, Jinlong; Purrer, Veronika; Krauss, Jonas; et al. NeuroImage: Clinical Vol. 52, p. 104058 - | Thanks for sharing #dzne #papers

Functional network reorganization after magnetic resonance-guided focused ultrasound thalamotomy in tremor-dominant Parkinson's disease patients.

Liu, Jinlong; Purrer, Veronika; Krauss, Jonas; et al. NeuroImage: Clinical Vol. 52, p. 104058 -

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New paper out: Type, severity, frequency and management of adverse reactions associated with ultrasound contrast agents: a systematic review and meta-analysis.: Ocagli, Honoria; Romanini, Laura; Llane, Adea; et al. European radiology Vol. 36, no. 10, p. 7671 - 7683 | Thanks for sharing #dzne #papers

Type, severity, frequency and management of adverse reactions associated with ultrasound contrast agents: a systematic review and meta-analysis.

Ocagli, Honoria; Romanini, Laura; Llane, Adea; et al. European radiology Vol. 36, no. 10, p. 7671 - 7683

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New paper out: NLRP3 Regulation in Neonatal Hypoxic-Ischemic Encephalopathy-Focus on Microglial Activation.: Burkard, Hannah; Bernis, Maria Eugenia; Bremer, Anna-Sophie; et al. International journal of molecular sciences Vol. 27, no. 17, p. 7853 - | Thanks for sharing #dzne #papers

NLRP3 Regulation in Neonatal Hypoxic-Ischemic Encephalopathy-Focus on Microglial Activation.

Burkard, Hannah; Bernis, Maria Eugenia; Bremer, Anna-Sophie; et al. International journal of molecular sciences Vol. 27, no. 17, p. 7853 -

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New paper out: Learning reorganizes dendritic and stabilizes axon initial segment inhibitory synapses in CA1 pyramidal neurons.: Klimmt, Hannah; Kuhn, Felix; Kappel, David; et al. Nature Communications Vol. 17, no. 1, p. 9791 | Thanks for sharing #dzne #papers

Learning reorganizes dendritic and stabilizes axon initial segment inhibitory synapses in CA1 pyramidal neurons.

Klimmt, Hannah; Kuhn, Felix; Kappel, David; et al. Nature Communications Vol. 17, no. 1, p. 9791

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New paper out: Fibronectin mediates APOE4-driven blood-brain barrier dysfunction in Alzheimer's disease.: Bhattarai, Prabesh; Yilmaz, Elanur; Cakir, Elif Öykü; et al. Nature aging Vol. 6, no. 9, p. 1901 - 1927 | Thanks for sharing #dzne #papers

Fibronectin mediates APOE4-driven blood-brain barrier dysfunction in Alzheimer's disease.

Bhattarai, Prabesh; Yilmaz, Elanur; Cakir, Elif Öykü; et al. Nature aging Vol. 6, no. 9, p. 1901 - 1927

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New paper out: Cyclosporin A triggers a RIG-I-mediated interferon response through multiple cellular processes.: Meier, Lars; Schauflinger, Martin; Neubecker, Pauline; et al. Scientific reports Vol. 16, no. 1, p. 28863 | Thanks for sharing #dzne #papers

Cyclosporin A triggers a RIG-I-mediated interferon response through multiple cellular processes.

Meier, Lars; Schauflinger, Martin; Neubecker, Pauline; et al. Scientific reports Vol. 16, no. 1, p. 28863

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New paper out: Deep FLASH-seq profiling of purified canine sensory neurons uncovers species-specific signatures relevant to pain and itch.: Ledesma Fernandez, Paula; Butler, Brandi; Theis, Heidi; et al. Pain Vol. 167, no. 10, p. 2391 - 2407 | Thanks for sharing #dzne #papers

Deep FLASH-seq profiling of purified canine sensory neurons uncovers species-specific signatures relevant to pain and itch.

Ledesma Fernandez, Paula; Butler, Brandi; Theis, Heidi; et al. Pain Vol. 167, no. 10, p. 2391 - 2407

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New paper out: Positioning equity at the core of European dementia research: a pan-European co-produced perspective from the PANEUCARE consortium.: Cardona, Maria Isabel; Giebel, Clarissa; Scerri, Anthony; et al. Frontiers in medicine Vol. 13, p. 1828363 | Thanks for sharing #dzne #papers

Positioning equity at the core of European dementia research: a pan-European co-produced perspective from the PANEUCARE consortium.

Cardona, Maria Isabel; Giebel, Clarissa; Scerri, Anthony; et al. Frontiers in medicine Vol. 13, p. 1828363

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New paper out: A world view: Considerations of sociocultural diversity in the study of subjective cognitive decline in Alzheimer's disease and related dementias.: Dubbelman, Mark A; Hill-Jarrett, Tanisha G; Chapman, Silvia; et al. Alzheimer's and dementia Vol. 22,… | Thanks for sharing #dzne #papers

A world view: Considerations of sociocultural diversity in the study of subjective cognitive decline in Alzheimer's disease and related dementias.

Dubbelman, Mark A; Hill-Jarrett, Tanisha G; Chapman, Silvia; et al. Alzheimer's and dementia Vol. 22, no. 9, p. e71779

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New paper out: Which methodologies and methods should be used for psychosocial intervention research in dementia? Protocol for a stakeholder-driven, multi-method Delphi study.: Bartels, Sara Laureen; D'Andrea, Federica; Burnand, Alice; et al. BMJ open Vol. 16, no.… | Thanks for sharing #dzne #papers

Which methodologies and methods should be used for psychosocial intervention research in dementia? Protocol for a stakeholder-driven, multi-method Delphi study.

Bartels, Sara Laureen; D'Andrea, Federica; Burnand, Alice; et al. BMJ open Vol. 16, no. 9, p. e122720 -

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New paper out: Innervated human cardiac muscle model reveals sympathetic drivers of KCNH2-associated arrhythmias.: Schneider, Lennart Valentin; Setya, Michael Gani; Bao, Guobin; et al. Nature Communications Vol. 17, no. 1, p. 9404 | Thanks for sharing #dzne #papers

Innervated human cardiac muscle model reveals sympathetic drivers of KCNH2-associated arrhythmias.

Schneider, Lennart Valentin; Setya, Michael Gani; Bao, Guobin; et al. Nature Communications Vol. 17, no. 1, p. 9404

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New paper out: Mechanistic characterization and inhibition of PAD4-dependent NETosis following experimental neonatal hypoxic-ischemic brain injury.: Bremer, Anna-Sophie; Bernis, Maria Eugenia; Burkard, Hannah; et al. Experimental neurology Vol. 406, p. 115994 - | Thanks for sharing #dzne #papers

Mechanistic characterization and inhibition of PAD4-dependent NETosis following experimental neonatal hypoxic-ischemic brain injury.

Bremer, Anna-Sophie; Bernis, Maria Eugenia; Burkard, Hannah; et al. Experimental neurology Vol. 406, p. 115994 -

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New paper out: Authors' Comments on 'Adaptive Deep Brain Stimulation for Parkinson's Disease: Navigating the Roadblocks to Clinical Implementation'.: Koeglsperger, Thomas; Scherer, Maximilian; Kühn, Andrea A; et al. Movement disorders Vol. 41, no. 8, p. 2225 - 2226 | Thanks for sharing #dzne #papers

Authors' Comments on 'Adaptive Deep Brain Stimulation for Parkinson's Disease: Navigating the Roadblocks to Clinical Implementation'.

Koeglsperger, Thomas; Scherer, Maximilian; Kühn, Andrea A; et al. Movement disorders Vol. 41, no. 8, p. 2225 - 2226

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New paper out: Prion protein (PrP) profiles in blood and CSF: insights into pre-symptomatic and symptomatic prion disease.: Laginha, Inês; Schmitz, Matthias; da Silva Correia, Ângela; et al. Brain communications Vol. 8, no. 5, p. fcag321 | Thanks for sharing #dzne #papers

Prion protein (PrP) profiles in blood and CSF: insights into pre-symptomatic and symptomatic prion disease.

Laginha, Inês; Schmitz, Matthias; da Silva Correia, Ângela; et al. Brain communications Vol. 8, no. 5, p. fcag321

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New paper out: Diagnostic performance of plasma pTau217 in genetically admixed South American populations.: Martino-Adami, Pamela V; Coutinho de Alvarenga, Joice; Freccero, Pilar; et al. Nature Communications Vol. 17, no. 1, p. 9464 | Thanks for sharing #dzne #papers

Diagnostic performance of plasma pTau217 in genetically admixed South American populations.

Martino-Adami, Pamela V; Coutinho de Alvarenga, Joice; Freccero, Pilar; et al. Nature Communications Vol. 17, no. 1, p. 9464

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