DZNE research center

@dzne.science

Dedicated to advancing the scientific understanding of neurodegenerative diseases - from mechanisms to diagnosis, therapy, and prevention (such as AD, PD or ALS). 🔗 Imprint: https://dzne.de/en/imprint 🔗 Data Protection: https://dzne.de/en/data-protection/

New paper out: Neurologische Manifestationen bei Patienten mit Post-COVID-19-Syndrom | Neurological manifestations in patients with post-COVID-19 syndrome: Franke, C.; Warnke, C.; Gorsler, A.; et al. DGNeurologie Vol. 4, no. 4, p. 276 - 280 | Thanks for sharing #dzne #papers

Neurologische Manifestationen bei Patienten mit Post-COVID-19-Syndrom | Neurological manifestations in patients with post-COVID-19 syndrome

Franke, C.; Warnke, C.; Gorsler, A.; et al. DGNeurologie Vol. 4, no. 4, p. 276 - 280

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New paper out: The Alzheimer's Disease Prediction Of Longitudinal Evolution (TADPOLE) Challenge: Results after 1 Year Follow-up: Marinescu, Razvan V.; Oxtoby, Neil P.; Young, Alexandra L.; et al. Machine learning for biomedical imaging Vol. 1, no. December 2021,… | Thanks for sharing #dzne #papers

The Alzheimer's Disease Prediction Of Longitudinal Evolution (TADPOLE) Challenge: Results after 1 Year Follow-up

Marinescu, Razvan V.; Oxtoby, Neil P.; Young, Alexandra L.; et al. Machine learning for biomedical imaging Vol. 1, no. December 2021, p. 1 - 60

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New paper out: Evidence-based care pathways for people with dementia and neurodegenerative disorders in Europe: a systematic review of models, integration of digital technologies, and quality indicators.: Cardona, Maria Isabel; Gakoudis, Parthena Nena;… | Thanks for sharing #dzne #papers

Evidence-based care pathways for people with dementia and neurodegenerative disorders in Europe: a systematic review of models, integration of digital technologies, and quality indicators.

Cardona, Maria Isabel; Gakoudis, Parthena Nena; Macijauskienė, Jūratė; et al. Frontiers in medicine Vol. 13, p. 1774318

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New paper out: Early Alzheimer´s disease blood biomarkers are associated with a higher risk for postoperative long-term cognitive decline: Insights from the FINDERI study.: Hansen, Niels; Sadlonova, Monika; Esselmann, Hermann; et al. Alzheimer's and dementia Vol.… | Thanks for sharing #dzne #papers

Early Alzheimer´s disease blood biomarkers are associated with a higher risk for postoperative long-term cognitive decline: Insights from the FINDERI study.

Hansen, Niels; Sadlonova, Monika; Esselmann, Hermann; et al. Alzheimer's and dementia Vol. 22, no. 7, p. e71631

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New paper out: Co-regulation of HIV control and cytomegalovirus pp65-specific IL-1β and TNF-α responses by genetic variants in the MHC region.: Ruijten, Suzanne D E; Dos Santos, Jéssica C; Rios-Vazquez, Victoria; et al. PLoS pathogens Vol. 22, no. 7, p. e1014355 - | Thanks for sharing #dzne #papers

Co-regulation of HIV control and cytomegalovirus pp65-specific IL-1β and TNF-α responses by genetic variants in the MHC region.

Ruijten, Suzanne D E; Dos Santos, Jéssica C; Rios-Vazquez, Victoria; et al. PLoS pathogens Vol. 22, no. 7, p. e1014355 -

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New paper out: Parkinson's disease genetics across diverse ancestries: an observational genetic study of causal and risk variants with translational implications: Lange, Lara M; Fang, Zih-Hua; Makarious, Mary B; et al. The lancet Vol. 25, no. 8, p. 741 - 754 | Thanks for sharing #dzne #papers

Parkinson's disease genetics across diverse ancestries: an observational genetic study of causal and risk variants with translational implications

Lange, Lara M; Fang, Zih-Hua; Makarious, Mary B; et al. The lancet Vol. 25, no. 8, p. 741 - 754

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New paper out: Evidence for early, clinically silent medial temporal lobe inflammation after CAR-T cell therapy.: Dubai, Marwa Al; Rebello, Mahima Verginia; Neumann, Katja; et al. European journal of cancer Vol. 244, p. 116925 - | Thanks for sharing #dzne #papers

Evidence for early, clinically silent medial temporal lobe inflammation after CAR-T cell therapy.

Dubai, Marwa Al; Rebello, Mahima Verginia; Neumann, Katja; et al. European journal of cancer Vol. 244, p. 116925 -

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New paper out: Anti-NMDAR encephalitis impairs intrinsic hippocampal dynamics through neuronal hypercoupling, hub dominance, and aberrant ensembles.: Rahmati, Vahid; Graf, Jürgen; Ceanga, Mihai; et al. Molecular psychiatry Vol. 31, no. 8, p. 4550 - 4562 | Thanks for sharing #dzne #papers

Anti-NMDAR encephalitis impairs intrinsic hippocampal dynamics through neuronal hypercoupling, hub dominance, and aberrant ensembles.

Rahmati, Vahid; Graf, Jürgen; Ceanga, Mihai; et al. Molecular psychiatry Vol. 31, no. 8, p. 4550 - 4562

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New paper out: Drawing a line: Differentiating mild from moderate dementia using the functional activities questionnaire.: Ersözlü, Ersin; Preis, Lukas; Aktuz, Aykut; et al. The journal of prevention of Alzheimer's disease Vol. 13, no. 8, p. 100630 - | Thanks for sharing #dzne #papers

Drawing a line: Differentiating mild from moderate dementia using the functional activities questionnaire.

Ersözlü, Ersin; Preis, Lukas; Aktuz, Aykut; et al. The journal of prevention of Alzheimer's disease Vol. 13, no. 8, p. 100630 -

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New paper out: Neuroimaging Correlates of Post-Stroke Pain After Ischemic Stroke: Secondary Analysis of the INSPiRE-TMS Trial.: Stegemann, Alina; Rios, Ana Sofia; Khalil, Ahmed; et al. Human brain mapping Vol. 47, no. 10, p. e70602 | Thanks for sharing #dzne #papers

Neuroimaging Correlates of Post-Stroke Pain After Ischemic Stroke: Secondary Analysis of the INSPiRE-TMS Trial.

Stegemann, Alina; Rios, Ana Sofia; Khalil, Ahmed; et al. Human brain mapping Vol. 47, no. 10, p. e70602

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New paper out: Value of MRI Outcomes for Preventive and Early-Stage Trials in Spinocerebellar Ataxias 1 and 3.: Rezende, Thiago J R; Petit, Emilien; Park, Young Woo; et al. Annals of Clinical and Translational Neurology Vol. 13, no. 7, p. 1452 - 1466 | Thanks for sharing #dzne #papers

Value of MRI Outcomes for Preventive and Early-Stage Trials in Spinocerebellar Ataxias 1 and 3.

Rezende, Thiago J R; Petit, Emilien; Park, Young Woo; et al. Annals of Clinical and Translational Neurology Vol. 13, no. 7, p. 1452 - 1466

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New paper out: Aquaporin-4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders.: Ranke, Jonas; Steinacker, Petra; Halbgebauer, Steffen; et al. Annals of Clinical and Translational Neurology Vol. 13, no. 7, p. 1498 - 1502 | Thanks for sharing #dzne #papers

Aquaporin-4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders.

Ranke, Jonas; Steinacker, Petra; Halbgebauer, Steffen; et al. Annals of Clinical and Translational Neurology Vol. 13, no. 7, p. 1498 - 1502

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New paper out: Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points.: Grobe-Einsler, Marcus; Maas, Vivian; Amin, Arian Taheri; et al. Annals of Clinical and Translational Neurology Vol. 13, no. 7, p. 1370 - 1378 | Thanks for sharing #dzne #papers

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points.

Grobe-Einsler, Marcus; Maas, Vivian; Amin, Arian Taheri; et al. Annals of Clinical and Translational Neurology Vol. 13, no. 7, p. 1370 - 1378

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New paper out: Survival estimates and their predictors in genetic frontotemporal dementia: an international, retrospective, cohort study: Bouzigues, Arabella; Grassi, Mario; Cantoni, Valentina; et al. The lancet Vol. 25, no. 8, p. 731 - 740 | Thanks for sharing #dzne #papers

Survival estimates and their predictors in genetic frontotemporal dementia: an international, retrospective, cohort study

Bouzigues, Arabella; Grassi, Mario; Cantoni, Valentina; et al. The lancet Vol. 25, no. 8, p. 731 - 740

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New paper out: Variational sparse Gaussian-process method for detecting spatially variable genes and cellular interactions in spatial transcriptomics.: Wang, Zhicong; Li, Jing; Xie, Liqing; et al. Briefings in bioinformatics Vol. 27, no. 4, p. bbag371 | Thanks for sharing #dzne #papers

Variational sparse Gaussian-process method for detecting spatially variable genes and cellular interactions in spatial transcriptomics.

Wang, Zhicong; Li, Jing; Xie, Liqing; et al. Briefings in bioinformatics Vol. 27, no. 4, p. bbag371

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New paper out: Spatio-temporal gait signatures across prodromal and early Parkinson's disease in two independent cohorts.: Zatti, Cinzia; Hansen, Clint; Rizzardi, Andrea; et al. Scientific reports Vol. 16, no. 1, p. 21897 | Thanks for sharing #dzne #papers

Spatio-temporal gait signatures across prodromal and early Parkinson's disease in two independent cohorts.

Zatti, Cinzia; Hansen, Clint; Rizzardi, Andrea; et al. Scientific reports Vol. 16, no. 1, p. 21897

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New paper out: HTZ-1/H2A.Z expression sustains transcriptional programs that regulate Caenorhabditis elegans lifespan.: Xie, Beijia; Scifo, Enzo; Menegatou, Ioanna-Maria; et al. Mechanisms of ageing and development Vol. 232, p. 112217 - | Thanks for sharing #dzne #papers

HTZ-1/H2A.Z expression sustains transcriptional programs that regulate Caenorhabditis elegans lifespan.

Xie, Beijia; Scifo, Enzo; Menegatou, Ioanna-Maria; et al. Mechanisms of ageing and development Vol. 232, p. 112217 -

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New paper out: Reply to the Letter to the Editor: Blind spots in radiology leadership regarding human resources and organization management in the era of artificial intelligence.: Wichtmann, Barbara D; Paech, Daniel; Pianykh, Oleg S; et al. European radiology Vol.… | Thanks for sharing #dzne #papers

Reply to the Letter to the Editor: Blind spots in radiology leadership regarding human resources and organization management in the era of artificial intelligence.

Wichtmann, Barbara D; Paech, Daniel; Pianykh, Oleg S; et al. European radiology Vol. 36, no. 8, p. 6842 - 6844

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New paper out: Miro1 mutations disrupt cellular calcium homeostasis via dysregulation of mitochondria-ER-contact-sites, rendering iPSC-derived neurons more susceptible to lipid peroxidation.: Bartalis, Anna E; Genschmar, Jack; Fitzgerald, Julia C; et al.… | Thanks for sharing #dzne #papers

Miro1 mutations disrupt cellular calcium homeostasis via dysregulation of mitochondria-ER-contact-sites, rendering iPSC-derived neurons more susceptible to lipid peroxidation.

Bartalis, Anna E; Genschmar, Jack; Fitzgerald, Julia C; et al. Neurobiology of disease Vol. 227, p. 107492 -

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New paper out: Synaptophysin density underestimates synapse counts in the human brain - An anatomical study on synaptoporin protein expression.: Woelfle, Sarah; Schön, Michael; Pedro, Maria T; et al. Neurobiology of disease Vol. 227, p. 107503 - | Thanks for sharing #dzne #papers

Synaptophysin density underestimates synapse counts in the human brain - An anatomical study on synaptoporin protein expression.

Woelfle, Sarah; Schön, Michael; Pedro, Maria T; et al. Neurobiology of disease Vol. 227, p. 107503 -

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