New paper led by Aimilia Vareli out now. nature.com/articles/s41... The lymphoma microenvironment stops BH3-mimetics working. In vitro/vivo/silico, we find inhibition of NFκB makes BH3-mimetics great again.🧵 @sussexbcr.bsky.social @bsmsmedschool.bsky.social @leukaemiauk.bsky.social @sussexcancer.org

Systems biology-enabled targeting of NF-κΒ and BCL2 overcomes microenvironment-mediated BH3-mimetic resistance in DLBCL - Cell Death & Disease

Cell Death & Disease - Systems biology-enabled targeting of NF-κΒ and BCL2 overcomes microenvironment-mediated BH3-mimetic resistance in DLBCL

nature.com

New paper led by @ejayawant.bsky.social 🎉 We review: - how computational biology is helping us understand lymphoma, - how machine learning and cell simulations make sense of vast amounts of data, - how models can personalise treatments to each person with lymphoma. portlandpress.com/biochemsoctr...

Multiple positions currently open for applications but with imminent dealines: - PhD studentship with Sally Wheelwright on cancer-related fatigue. - PhD studentship with Chris Pepper on multiple myeloma. - Postdoc with @mitchell.science on cancer systems biology. sussexcancer.org/jobs

jobs — Sussex Cancer Research Centre

sussexcancer.org

We're hosting our 4th annual research away day on Fri 26th Sept 12.30-17.30 at the AmEX stadium in Falmer, Brighton. If you're a local blood cancer patient, industry leader or healthcare professional in the region and you'd like to attend please reach out: sussex.haematology@sussex.ac.uk 1/n

🧵1/ My partner & I just started doing cryptic crosswords, and it's made me think about navigating the world as a neurodivergent person.

🧵1/ 🔬 A postdoc in numbers (and life beyond the lab) As I wrap up my postdoc with @mitchell.science at @bsmsmedschool.bsky.social, I've been reflecting on everything that’s changed since I started in 2021. A lot can happen in a few years…