Emma Derrick

@emderrick.bsky.social

PhD candidate in the Shapiro lab at McGill studying evolution within natural aquatic microbial communities

The first chapter of my PhD is finally out! I learned 1) studying evolution within natural communities is difficult and 2) the publishing process is more difficult See below for a great summary by Jesse

Jesse Shapiro@bjesseshapiro.bsky.social · 7d ago

Our latest, spearheaded by the truly indefatigable @emderrick.bsky.social in which we search for selective sweeps in nature and genetic targets of selection within a species in the context of a diverse background community @isme-microbes.bsky.social doi.org/10.1093/isme... 🧵 1/n

Latest preprint from the lab is also the first data paper from @emderrick.bsky.social ! We asked if an experimentally applied selective pressure (the herbicide Roundup) causes genome-wide or gene-specific sweeps in aquatic bacteria in a semi-natural (mesocosm) context. 1/n

Photo of experimental ponds, each holding 1000 L of lake water at the McGill Gault Nature Reserve
bioRxiv Evolutionary Biology@biorxiv-evobio.bsky.social · 2y ago

A glyphosate-based herbicide selects for genetic changes while retaining within-species diversity in a freshwater bacterioplankton community https://www.biorxiv.org/content/10.1101/2024.09.17.613573v1

New from super student Sana Naderi! The punch line: deer have high within-host viral diversity compared to humans, cats, dogs, or minks. This is likely due to larger viral populations sizes or more chronic infections, which could explain the rapid viral evolution seen previously in deer.

bioRxiv Genomics@biorxiv-genomic.bsky.social · 3y ago

Within-host genetic diversity of SARS-CoV-2 across animal species https://www.biorxiv.org/content/10.1101/2024.04.03.587973v1

Ever wonder if V. cholerae loses genetic diversity due to bottlenecks as it passes through the gut? We have a little preprint about that! The answer, based on sequencing 200 genomes from 10 patients’ vomit and stool, is: maybe a little but not much!

bioRxiv Microbiology@biorxiv-microbiol.bsky.social · 3y ago

Diversity of Vibrio cholerae O1 through the human gastrointestinal tract during cholera https://www.biorxiv.org/content/10.1101/2024.02.08.579476v1

I'm so excited to share this new paper (with my great advisor @nanditagarud.bsky.social), on selective sweeps in gut bacteria. In this long thread, I’m going to go over our results, but I also want to highlight some of the incredible work that set the stage for us www.biorxiv.org/content/10.1...

Pervasive selective sweeps across human gut microbiomes

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