In 1950, the Noyes criteria was established for determining the optimal window of implantation @gregoryburns.bsky.social, @emmanuelpaul.bsky.social, Nataki C. Douglas & team now identify an epithelial receptivity signature & stromal changes supporting embryo implantation: doi.org/10.1172/jci....
Thrilled to share our latest @JCI_Insight paper with @NatakiDouglas and team! We mapped human endometrial cell states across the menstrual cycle and defined the GERM (glandular epithelium receptivity module) — a 556-gene signature marking the window of implantation. insight.jci.org/articles/vie...
JCI Insight - Single-cell mapping of human endometrium and decidua reveals epithelial and stromal contributions to fertility
insight.jci.org
Check out our newest work in collaboration with Dr. Nataki Douglas! @emmanuelpaul.bsky.social @aroralab.bsky.social www.biorxiv.org/content/10.1...
Single cell mapping of the human endometrium and first trimester decidua identifies distinct epithelial and stromal cell contributions to fertility
The human endometrium undergoes dynamic changes across the menstrual cycle to establish a receptive state for embryo implantation. Using bulk and single-cell RNA sequencing, we characterized gene expr...
biorxiv.org
Our latest publication is now online! Spatial Transcriptomic Analysis Identifies Epithelium-Macrophage Crosstalk in Endometriotic Lesions: iScience www.cell.com/iscience/ful...
Spatial Transcriptomic Analysis Identifies Epithelium-Macrophage Crosstalk in Endometriotic Lesions
The mechanisms underlying the pathophysiology of endometriosis, characterized by the presence of endometrium-like tissue outside the uterus, remain poorly understood. This study aimed to identify cell...
cell.com
