While Ed can’t make #Nido2026, the lab is well-represented by Max Erdmann, and @rebee.bsky.social ! They will be sharing some of the labs findings on coronavirus replication! Catch Max’s talk tomorrow (Wed) at 3:25, and Rebee’s poster C-0036
Emmottlab
@emmottlab.bsky.social
Lab news and updates for the Emmott lab, RNA virology & proteomics at the Centre for Proteome Research, University of Liverpool, UK Lab website: emmottlab.org
Funded PhD opportunity! (UK students only due to funder restrictions). Investigating cellular heterogeneity in tendon homeostasis and ageing using single-cell proteomics. Deadline 31st July. Project is a collaboration between the Peffers, Emmott and Thorpe labs on equine tendons. Start Oct 2026.
PhD Programmes, Research Projects & Studentships in the UK & Europe
FindAPhD is a comprehensive guide to PhD studentships and postgraduate research degrees
findaphd.com
In other lab news, Ed was promoted to Professor of Virology & Proteomics. Huge thanks to the team for all their work and support! And to the various mentors and supporters who have helped along the way. We have lots more exciting science coming in the near future!
MSCA Postdoctoral Fellowships call opening soon. If you are a strong candidate and interested in submitting a fellowship with us, we have opportunities in several areas of virology/proteomics. See emmottlab.org Call details/eligibility: marie-sklodowska-curie-actions.ec.europa.eu/funding/msca...
MSCA Postdoctoral Fellowships 2026
MSCA Postdoctoral Fellowships enhance the creative and innovative potential of researchers holding a PhD and who wish to acquire new skills through advanced training, international, interdisciplinary ...
marie-sklodowska-curie-actions.ec.europa.eu
New preprint! Current T7-based MNV reverse genetics can be performed by co-transfecting plasmids encoding T7 RNA polymerase and vaccinia capping enzymes. We see a further 100-1000-fold boost in titres by incorporating CD300lf-expressing BSR-T7 cells into this system. www.biorxiv.org/content/10.6...
biorxiv.org
Funded PhD studentship (UK students only) available on clinical proteomics, application deadline 22nd March for Oct 2026 start! This project seeks to understand treatment responses to exacerbations experienced by people with CF using proteomics. www.findaphd.com/phds/project...
Proteomic Signatures of Treatment Response During Pulmonary Exacerbations in Cystic Fibrosis at University of Liverpool on FindAPhD.com
PhD Project - Proteomic Signatures of Treatment Response During Pulmonary Exacerbations in Cystic Fibrosis at University of Liverpool, listed on FindAPhD.com
findaphd.com
Congrats to Dr @stephenholmes.bsky.social on passing his PhD viva today! Thanks to examiners Al Darby and @mtrost.bsky.social!
For those who missed the British science festival in September, the recordings and mini documentary for antiviral roller skating are now out!
🚨 Big news! We’re thrilled to announce the release of both the Behind-the-Scenes Mini-Doc and the Full Recording of Antiviral Roller Skating! 🛼✨ Now you can watch the mini-doc to see how it all came together behind the scenes: youtu.be/0nevSD1wrdg And the full performance: youtu.be/mp995EBB3Bo
Another new preprint! This time looking at flavivirus NS5 interactions with our collaborator Armando Arias - www.biorxiv.org/content/10.6...
Mitophagy-related prohibitin 2 is an orthoflavivirus restriction factor targeted for degradation during infection
Mitophagy selectively removes depolarised and damaged mitochondria, promoting cell viability. Some members of the Orthoflavivirus genus activate mitophagy to allow extended replication times in a surv...
biorxiv.org
New preprint from the lab, and joint first authors @biomarkella.bsky.social and @stephenholmes.bsky.social! Single-cell phenotypic analysis and multiplet detection through incorporation of microscopy data into cellenONE-based single-cell proteomic data analysis www.biorxiv.org/content/10.6...
Single-cell phenotypic analysis and multiplet detection through incorporation of microscopy data into cellenONE-based single-cell proteomic data analysis
The reliability of single-cell proteomics (SCP) is intrinsically linked to the fidelity of cell isolation; however, the identification of co-isolated cells (doublets or multiplets) remains a persisten...
biorxiv.org
New preprint: Viral protease-mediated polyprotein processing in human astroviruses Great collaboration with Lulla lab. And the first of @leandroxneves.bsky.social proteolysis stories. More coming soon! www.biorxiv.org/content/10.1...
Viral protease-mediated polyprotein processing in human astroviruses
Positive-sense RNA viruses often encode large polyproteins that are proteolytically processed by viral and host proteases into functional replication proteins. Astroviruses infect intestinal and neuro...
biorxiv.org
New preprint: IFIT3 controls IFIT1 accumulation and specificity preventing self mRNA targeting during the innate immune response. www.biorxiv.org/content/10.1... Led by Renata Fleith from the Sweeney lab.
biorxiv.org
Funded PhD opportunity through the DiMeN DTP: studying HEV proteolysis. You’ll be primarily based in the Herod lab at Leeds, and work with us on the use of MS-based proteomics to study proteolysis! www.findaphd.com/phds/project...
MRC DiMeN Doctoral Training Partnership: Molecular Regulation of Proteolysis by Hepatitis E Virus as a Basis for Therapeutic Intervention at University of Leeds on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Molecular Regulation of Proteolysis by Hepatitis E Virus as a Basis for Therapeutic Intervention at University of Leeds, listed on FindAPhD.com
findaphd.com
We are still buzzing from our show! Here’s some snaps of what you missed… in case you were wondering…. Huge thank you to the whole production team and the people who made this happen! @microbiologysociety.org @britsciassoc.bsky.social @emmottlab.bsky.social @livuninews.bsky.social #BSF25
The lab is being represented at the IX International Calicivirus Conference in Banff by @tartanvirus.bsky.social! Catch Frazer to talk protease substrates and proteomics.
Led by @idb-virology.bsky.social, the lab is contributing to #BSF25 with a performance of antiviral roller skating! Working with Liverpool roller birds, and supported by the BSF and @microbiologysociety.org
📣 Introducing "Antiviral Roller Skating"! ✨️🦠🛼✨️ Debuting at the British Science Festival 2025 #BSF25 in Liverpool! Exploring viruses & antivirals through movement & play! Friday 12 Sep, 18.30 @unitytheatre.bsky.social FREE tickets: britishscienceassociation-tickets.ticketsolve.com/ticketbooth/...
👨🔬Scientific Advisors Drs. Max Edrmann & Ed Emmott @edemmott.bsky.social 🎭 Inspiration: "Bus Regulation: The Musical" by Ellie Harrison @ellieharrison.bsky.social 💷 Funded by @microbiologysociety.org & @britishscienceassociation.bsky.social #bsf25 #scicomm #sciencecommunication #skating #sciart
🤝 A collaboration between @liverpooluni.bsky.social & Liverpool Roller Birds ✍️🎬 Written, Directed & Produced by Dr. I'ah Donovan-Banfield @idb-virology.bsky.social 👯♀️Choreographed by Ani Bosco 📸 Director of Photography Dr. Rebee Penrice-Randal @rebee.bsky.social 📹 Videography by Paroketh Films
New paper: collaboration with Cambridge on EMCV 2B* now published journals.asm.org/doi/10.1128/...
Encephalomyocarditis virus protein 2B* interacts with 14-3-3 proteins through a phosphorylated C-terminal binding motif | mBio
Encephalomyocarditis virus (EMCV) infects a range of species, causing economically important reproductive disorders in pigs and encephalitis and myocarditis in rodents. Due to its wide host range, it ...
journals.asm.org
Congratulations to Markella Loi from the @emmottlab.bsky.social on winning the Early Career Award for #BSPR2025 and congratulations to @hannahmayging.bsky.social on being the runner
We have projects available on single-cell proteomics, including methods development, and applications to antiviral development and resistance. If you have a strong background in proteomics and are considering an MSCA, get in touch! marie-sklodowska-curie-actions.ec.europa.eu/news/msca-op...
MSCA opens €404.3 million call for Postdoctoral Fellowships
Postdoctoral Fellowships offer researchers holding a PhD the opportunity to acquire new skills through advanced training and international, interdisciplinary, and inter-sectoral mobility.
marie-sklodowska-curie-actions.ec.europa.eu
Nikolai and his group are based at Northeastern University and have been pioneers in the field of single cell proteomics. He will talk about the methods his lab has worked on for multiplexed approaches in SCP, including plexDIA
As we get ready for the British Society for Proteome Research annual meeting in Liverpool (July 7-9th), we will start highlighting our amazing speakers. First is @slavov-n.bsky.social who will talk to us about Biological and technological frontiers for single-cell proteomics.
First 2025 paper: delighted to have contributed to this paper on the emergence of a new subgenomic mRNA in SARS-CoV-2 from the Bauer lab journals.plos.org/plosbiology/...
Emergence of SARS-CoV-2 subgenomic RNAs that enhance viral fitness and immune evasion
Coronaviruses can evolve novel transcription regulatory sequences, generating new RNA transcripts during human infection. This study identifies a prevalent subgenomic RNA in SARS-CoV-2, which produces...
journals.plos.org
Another PhD studentship is available for Oct 2025 start! In a collaboration between the @pirbrightinst.bsky.social and us, you will be investigating the role of novel avian coronavirus accessory genes. See here for more details! www.findaphd.com/phds/project... Deadline 17 Feb, funded for UK only.
Investigation of Novel Accessory Proteins in the Replication of Infectious Bronchitis Virus at The Pirbright Institute on FindAPhD.com
PhD Project - Investigation of Novel Accessory Proteins in the Replication of Infectious Bronchitis Virus at The Pirbright Institute, listed on FindAPhD.com
findaphd.com
The deadlines for our MRC-funded studentships have now passed, but a funded studentship through the BBSRC NWD DLA is now available for Oct 2025 start in single cell mass spectrometry. See findaphd for more details or drop Ed an email. www.findaphd.com/phds/project...
BBSRC NWD CASE: Expanding single-cell proteomics into single-cell multi-Omics at University of Liverpool on FindAPhD.com
PhD Project - BBSRC NWD CASE: Expanding single-cell proteomics into single-cell multi-Omics at University of Liverpool, listed on FindAPhD.com
findaphd.com
Reminder - if you are a new PI in UK virology and you aren’t yet registered for RIVR2025 on Jan9-10th in Liverpool, registration closes on December 5th! If you are a new group leader in virology in the UK and aren’t yet on the RIVR mailing list, get in touch to be added.
Loading a mass spec and a nanopore in the same day! Thrilled to be learning another omics method in the @emmottlab.bsky.social 🧬