Weight loss reduces intermuscular adipose tissue and liver fat compared to exercise: implications for muscle quality and metabolic health. Read more in #JCEM: https://bit.ly/4fNM3lK #IntermuscularAdiposeTissue #Lipidomics #obesity @endocrinesociety.bsky.social

Testosterone protects from metabolic syndrome-associated lung dysfunction in a high-fat diet rabbit model. Read more in #Endocrinology: https://bit.ly/4wNAIb8 #MetabolicSyndrome #HighFatDiet @endocrinesociety.bsky.social

Development of Graves orbitopathy after thyroidectomy for thyroid cancer. Read more in #JCEM Case Reports: https://bit.ly/4feP4eL #GravesDisease #GravesOrbitopathy @endocrinesociety.bsky.social

Development of Graves orbitopathy after thyroidectomy for thyroid cancer

Abstract. We present a case of a 76-year-old female with a history of papillary thyroid cancer treated with a total thyroidectomy, central neck dissection,

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Epigenetics and childhood obesity: DNA methylation coordinates environment and gene regulation. Read more in #EndocrineReviews: https://bit.ly/4wffPWz #ChildhoodObesity #EpigeneticRegulation @endocrinesociety.bsky.social

Psychiatric morbidity following liothyronine exposure in autoimmune hypothyroidism: a Swedish nationwide cohort study. Read more in #JES: https://bit.ly/4yzkGU3 #LT3 #HashimotoThyroiditis @endocrinesociety.bsky.social

Psychiatric morbidity following liothyronine exposure in autoimmune hypothyroidism: a Swedish nationwide cohort study

AbstractContext. Levothyroxine (LT4) is the primary treatment of hypothyroidism. Despite adequate LT4 substitution some patients experience symptoms and th

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Utility of genomic sequencing classifier in managing cytologically indeterminate oncocytic thyroid nodules. Read more in #JCEM: https://bit.ly/4hoXRfA #ThyroidNodule #IndeterminateCytology @endocrinesociety.bsky.social

Utility of genomic sequencing classifier in managing cytologically indeterminate oncocytic thyroid nodules

AbstractContext. Oncocytic cells can occur in benign and malignant thyroid nodules, posing a diagnostic challenge. This has reduced the diagnostic performa

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Kisspeptin made in the preoptic area is required for normal estradiol-induced LH surges and optimal fertility in females. Read more in #Endocrinology: https://bit.ly/4b6hiGa #LHSurge #Kisspeptin #GnRH @endocrinesociety.bsky.social

Kisspeptin made in the preoptic area is required for normal estradiol-induced LH surges and optimal fertility in females

Abstract. Ovulation is triggered by a surge in luteinizing hormone (LH) secretion from the pituitary. The LH surge is itself driven by a surge in gonadotro

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Tirzepatide-associated interstitial kidney injury. Read more in #JCEM Case Reports: https://bit.ly/4yyFlaO #Tirzepatide #DrugInducedKidneyInjury @endocrinesociety.bsky.social

Relationship between histopathological findings and RAI in non-papillary follicular cell–derived thyroid carcinoma. Read more in #JES: https://bit.ly/4fsVKFa #DifferentiatedHighGradeThyroidCarcinoma #FollicularThyroidCarcinoma @endocrinesociety.bsky.social

Integrative genetic and liver transcriptomic analyses identify TRIB1AL as a target for steatotic liver disease. Read more in #JCEM: https://bit.ly/45gJMti #TRIB1AL #LiverProtemics @endocrinesociety.bsky.social

Mineralocorticoid and glucocorticoid receptor cooperation drives advanced phenotypes in triple-negative breast cancer. Read more in #Endocrinology: https://bit.ly/4b6V0nL #TripleNegativeBreastCancer #MineralcoticoidReceptorNR3C2Gene @endocrinesociety.bsky.social

Mineralocorticoid and glucocorticoid receptor cooperation drives advanced phenotypes in triple-negative breast cancer

Abstract. Oncogenic cell signaling, including the activation of cellular stress or cytokine-induced pathways, is a hallmark of cancer. In triple-negative b

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Perinatal organophosphate flame-retardant exposure alters adult stress axis and avoidance behavior in mice. Read more in #Endocrinology: https://bit.ly/3RbBHTp #FlameRetardants #EndocrineDisruption #HPAAxis @endocrinesociety.bsky.social

Mkrn3, Dlk1, and Mecp2 have distinct hypothalamic expression patterns across pubertal maturation in male and female mice. Read more in #JES: https://bit.ly/4wizTqC #puberty #hypothalamus @endocrinesociety.bsky.social

Mkrn3, Dlk1, and Mecp2 have distinct hypothalamic expression patterns across pubertal maturation in male and female mice

Abstract. Pubertal onset is driven by the reactivation of the hypothalamic-pituitary-gonadal (HPG) axis, a process orchestrated by a complex interplay of s

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Acromegaly and cardiovascular disease: mechanisms, clinical impact, and evolving management. Read more in #EndocrineReviews: https://bit.ly/4oV9ug1 #acromegaly #GrowthHormoneResponse @endocrinesociety.bsky.social

Acromegaly and cardiovascular disease: mechanisms, clinical impact, and evolving management

Abstract. Cardiovascular disease is one of the most common and serious complications of acromegaly and a leading contributor to reduced life expectancy in

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Unexpected resolution of chronic gastroesophageal reflux disease with testosterone replacement therapy. Read more in #JCEM Case Reports: https://bit.ly/4v3vjLI #GastroesophagealRefluxDisease #hypogonadism @endocrinesociety.bsky.social

Unexpected resolution of chronic gastroesophageal reflux disease with testosterone replacement therapy

Abstract. A 63-year-old man with a chronic, 30-year, history of gastroesophageal reflux disease (GERD) that required long-term proton pump inhibitor (PPI)

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Melatonin improves postprandial hypoglycemia: an unusual presentation of insulinoma. Read more in #JCEM Case Reports: https://bit.ly/4algJYJ #insulinoma #melatonin @endocrinesociety.bsky.social

Melatonin improves postprandial hypoglycemia: an unusual presentation of insulinoma

Abstract. Insulinoma is the most prevalent neuroendocrine tumor of the pancreas, presenting with a spectrum of neuroglycopenic symptoms. This case report d

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Effects of saccharin on insulin sensitivity in adult, overweight individuals without diabetes: a real-world pilot study. Read more in #JES: https://bit.ly/4wbxEWb #saccharin #InsulinResistance #Overweight @endocrinesociety.bsky.social

Effects of saccharin on insulin sensitivity in adult, overweight individuals without diabetes: a real-world pilot study

AbstractContext. It has been suggested that consumption of saccharin, a widely used artificial sweetener, decreases insulin sensitivity in rodents and huma

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Hyperthyroidism and Birth Defects: The Roles of Maternal Thyroid Function and Thyroid Autoantibody Positivity. Read more in #JCEM: https://bit.ly/4vvGcY3 #malformations #carbimazole #propylthiouracil @endocrinesociety.bsky.social

NR3C1 is required for normal somatotrope differentiation and Foxo1 expression in pituitary. Read more in #Endocrinology: https://bit.ly/4uQfkkl #Glucocorticoids #NR3C1 #somatotrope @endocrinesociety.bsky.social

NR3C1 is required for normal somatotrope differentiation and Foxo1 expression in pituitary

Abstract. Glucocorticoids are an important signal for the differentiation of many types of cells. Consistent with this, several studies have demonstrated t

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Ultra-rapid prolactin normalization with cabergoline in a premenopausal woman with epilepsy and giant prolactinoma. Read more in #JCEMCaseReports: https://bit.ly/4afcMVs #Cabergoline #epilepsy #GiantProlactinoma @endocrinesociety.bsky.social

Glycated CD59, a Novel Biomarker for Gestational Diabetes. Read more in #EndocrineReviews: https://bit.ly/3QqbEYl #GestationalDiabetesMellitus #GlycatedCD59 #biomarker @endocrinesociety.bsky.social

Potential risk of neoplasms with fezolinetant: clinical evidence, mechanisms, and post-marketing implications. Read more in #JES: https://bit.ly/4acRKqx #Fezolinetant #menopause #neoplasms @endocrinesociety.bsky.social

Bone turnover in arginine vasopressin deficiency: a comparative study with primary polydipsia and healthy controls. Read more in #JCEM: https://bit.ly/4vp8PGf #ArginineVasopressinDeficiency #PrimaryPolydipsia #BoneTurnoverMarkers @endocrinesociety.bsky.social

Generation of a prop1 knockin zebrafish enables single-cell transcriptomics of early pituitary development. Read more in #Endocrinology: https://bit.ly/4oFnGtl #EarlyPituitaryDevelopment #zebrafish #SingleCellTranscriptomics @endocrinesociety.bsky.social

Plasma metabolites after 10-weeks of glucose vs fructose-sweetened beverages in subjects with overweight/obesity. Read more in #JES: https://bit.ly/4vwOL4H #FructoseMetabolism #Metabolomics @endocrinesociety.bsky.social

Hypoglycemia in diabetes with low-affinity insulin antibody successfully improved by treating sleep apnea syndrome. Read more in #JCEMCaseReports: https://bit.ly/4aUCBKv #Hypoglycemia #InsulinAntibody #SleepApneaSyndrome @endocrinesociety.bsky.social

High Body Mass Index as a Causal Risk Factor for Vascular-Related Dementia: A Mendelian Randomization Study. Read more in #JCEM: https://bit.ly/44pCMd6 #BMI #VascularRelatedDementia #MendelianRandomization @endocrinesociety.bsky.social

Biological sex affects human islet gene expression and mitochondrial function in type 2 diabetes. Read more in #Endocrinology: https://bit.ly/4xME93l #HumanIsletGeneExpression #T2D @endocrinesociety.bsky.social

Biological sex affects human islet gene expression and mitochondrial function in type 2 diabetes

Abstract. The clinical characteristics of type 2 diabetes (T2D) differ between the sexes. For example, the risk of T2D is higher in males than in premenopa

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Longitudinal Study of Plasma Metabolites During Menopause and Their Associations With Later Onset of Metabolic Syndrome. Read more in #JCEM: https://bit.ly/4xUVqr8 #menopause #Metabolomics #glutamate @endocrinesociety.bsky.social

What did you think of our #JES Focused Collection: Endocrine-disrupting Chemicals: Environmental Health, Endocrinology, & Beyond @endosocjournals.bsky.social? Read & share our articles, and thanks to Associate Editor Andrea C. Gore, PhD: https://bit.ly/4xzXc0w #EDCs