Really happy to see this one out! Great work by @lalangohr.bsky.social, Ilse Kaaja and the whole team. 🩸🧬 @mlbiomed.bsky.social @fimm-uh.bsky.social

@lalangohr.bsky.social · 2mo ago

Our results show that ERCC6L2 disease patients' erythroid cells exhibit cell cycle and ferroptotic stress signatures already before malignant transformation, which persist despite somatic TP53 mutations. Langohr, Kaaja et al. @hemasphere-journal.bsky.social, doi.org/10.1002/hem3...

Upcoming FIMM dissertation! 📢 MSc Veera Timonen from @epitkanen.bsky.social's group will defend her doctoral dissertation "Multimodal investigation of hematological features in healthy blood donors" @helsinki.fi on 27 March at 13:00. Welcome! 🔗 tapahtumat.helsinki.fi/en-FI/page/6...

Our new preprint: dual-task learning in >17k cancer WGS. Somatic variant models can transfer across datasets, but dataset shift strongly affects performance. Cross-cohort validation is essential. www.medrxiv.org/content/10.6... @fimm-uh.bsky.social @mlbiomed.bsky.social

Pan-cancer tumour classification and risk stratification from whole-genome somatic variants via dual-task representation learning

Tumour typing from whole-genome sequencing is increasingly accurate, yet molecular subtyping from somatic variants remains challenging because of tumour heterogeneity and inconsistent clinical annotat...

medrxiv.org

📢As part of the Nordic EMBL Partnership for Molecular Medicine, @fimm-uh.bsky.social is now recruiting doctoral researchers in the FIMM-EMBL International PhD Programme. tinyurl.com/553jzfuy Deadline for application February 6, 2026 👇

FIMM-EMBL International PhD Programme | HiLIFE – Helsinki Institute of Life Science | University of Helsinki

As part of the Nordic EMBL Partnership for Molecular Medicine, outstanding doctoral researchers are recruited to the institute-level rotation programme through the annual call. The recruited doctoral ...

tinyurl.com

Grateful to @syopasaatio.bsky.social and donors for supporting our work at @mlbiomed.bsky.social! Thanks to this grant, we can develop new computational approaches for multimodal precision oncology. @fimm-uh.bsky.social

Syöpäsäätiö@syopasaatio.bsky.social · 9mo ago

Syöpäsäätiön vuosittain saamilla lahjoitusvaroilla tuetaan monipuolisesti syövän tutkimushankkeita - kiitos lahjoittajien ❤️ Nyt jaamme jälleen syöpätutkimukseen ennätysmäärän apurahoja, yhteensä 8 miljoonaa euroa. Lue lisää täältä: syopasaatio.fi/syopasaatio-... #syöpätutkimus #apurahat #tiede

Excited to share our latest pre-print on profiling DNA adducts with nanopore sequencing! This study was led by Yrjö Koski, who developed a computational toolkit called IonStats, and identified several compound-specific effects caused by genotoxic compounds. www.biorxiv.org/content/10.1...

Compound-specific DNA adduct profiling with nanopore sequencing and IonStats

Covalently bound DNA adducts are mutation precursors that contribute to aging and diseases such as cancer. Accurate detection of adducts in the genome will shed light on tumorigenesis. Commonly used a...

biorxiv.org