Very excited for the upcoming "Mechanobiology of Infection" meeting we are organizing with Alexandre Persat and Daria Bonazzi. Thanks to @biophysicalsoc.bsky.social Society for their support - looking forward to it! Abstract submission and registration here: www.biophysics.org/meetings-eve...

Listeria-infected macrophages promote biomechanical alterations in endothelial cell monolayers for transmigration

Listeria-infected macrophages promote biomechanical alterations in endothelial cell monolayers for transmigration

Intracellular pathogens like Listeria exploit macrophages to cross endothelial barriers and spread systemically. Muenkel et al. show that exposure to infected macrophages weakens contractile forces within the endothelial monolayer and promotes macrophage transmigration. This response is driven by direct cell-cell interactions, with cytokines exerting only minor and transient effects.

dlvr.it

Check out our newest publication in @cp-cellreports.bsky.social #Mechanobiology #HostPathogen #Listeria

Effie Bastounis@effiebastounis.bsky.social · 5mo ago

I'm excited to share our paper on how infected #macrophages promote #biomechanical alterations in #endothelia to transmigrate, published in @cp-cellreports.bsky.social! Thanks to all contributors, @sergemostowylab.bsky.social and @cmfi.bsky.social for the support. Here: www.cell.com/cell-reports...

Bastounis lab had a great time at @cellmech2025.bsky.social — such an engaging and well-organized #Mechanobiology conference in Leuven 🙌 Thanks to everyone for the inspiring exchanges! And big congrats to our lab member @hundsdorfer.bsky.social for winning the Best PhD Student Poster Prize 🎉

The Bastounis Lab is at #CellMech2025 in Leuven 🇧🇪! We explore how mechanics shape infection: from epithelial entry to endothelial barriers. 📅 Sept 30: Raúl Aparicio Yuste & Lara Hundsdorfer 📅 Oct 1:Julio César Sánchez Rendón, Marie Münkel, Nadine Oder& I Excited for inspiring discussions! 🚀