Eswarappa Lab IISc

@eswarappalab.bsky.social

Traversing through the regulation of translation at its start & stop and looking into teeny-tiny tardigrades. PI: Sandeep M Eswarappa | Indian Institute of Science Bangalore Lab website: https://sites.google.com/view/dr-sandeep-m-eswarappa/home?authuser=0

How short can a degron be? A compact, genetically encoded, 9-aa tunable degron that drives MDM2-dependent degradation enabling precise control of protein levels from yeast to human cells. Thanks to @eswarappalab.bsky.social for the opportunity to explore this in yeast. #Degron #Yeast #CellBiology 🧬

Bild
Eswarappa Lab IISc@eswarappalab.bsky.social · 7mo ago

Interested in tunable protein degradation? Check out our new preprint describing a compact, portable degron derived from MTCH2: doi.org/10.64898/202... Led by Lekha EM Saubhik Som Ramon Boro Sandeep Eswarappa Great collaboration w/ Anubhav Dhar Eepsitha @syncellbiolab.bsky.social #iiscbangalore