A new study explores intraoperative high-frequency ultrasound as a tool to identify capsular abnormalities and guide frozen section sampling in thyroid follicular neoplasms, with the aim of improving diagnostic sensitivity and accuracy. 🔗 doi.org/10.1530/ETJ-26-0040

Introducing Clinical Reasoning, a new article type in the European Thyroid Journal. If you are interested in submitting a Clinical Reasoning article, we'd be pleased to hear your proposal. Simply email etj@bioscientifica.com.

✈️ See you in Porto! The European Thyroid Journal will be attending the 47th Annual Meeting of the European Thyroid Association. If you're thinking about your next publication, stop by for a chat & learn more about publishing with the official journal of the European Thyroid Association. #ETA2026

New Consensus Statement: Management of thyroid storm Developed by an expert panel, this document brings together current evidence & expert consensus to support the management of thyroid storm. 🔗https://doi.org/10.1530/ETJ-26-0043

New research by Anke Daser et al. identifies TNFα as a central regulator linking inflammation to adipogenic suppression, profibrotic signaling, and extracellular matrix remodeling in a thyrotropin receptor-immunized mouse model of thyroid eye disease. 🔗Read the research: doi.org/10.1530/ETJ-25-0407

💙 August is Thyroid and Pregnancy Awareness Month. Help advance understanding of thyroid disease in pregnancy & contribute to the evidence base informing care by contributing to the ETJ Special Collection on Thyroid Disease and Pregnancy 🔗 journals.bioscientifica.com/etj/pages/pregnancy/

A recent study used an ex vivo human placental perfusion model to investigate the role of MCT8 in placental thyroxine (T4) transfer and whether impaired maternal thyroid hormone transport may contribute to neurodevelopmental impairment in MCT8 deficiency. 🔗 doi.org/10.1530/ETJ-26-0003

Expert Consensus on the Management of Myxoedema Coma This document provides recommendations for the diagnosis, initial resuscitation, and definitive management of myxoedema coma based on clinician expertise and experience. Link to statement: doi.org/10.1530/ETJ-26-0044

As advances in immunology, genomics, and precision medicine accelerate, new insights are reshaping how we understand, diagnose, and manage autoimmune thyroid disorders. 📣Contribute to our latest collection and help advance the field: journals.bioscientifica.com/etj/pages/au...

NEW GUIDELINES 2026 ETA guideline on interference in immunoassay measurements used in assessment of thyroid function Read the guidelines: doi.org/10.1530/ETJ-26-0011

A new review by Laura Croce et al. critically reviews current evidence & emerging topics in the interaction between obesity and the thyroid axis. The review spotlights the complexity of thyroid responses across different degrees of obesity & during weight loss. 🔗 doi.org/10.1530/ETJ-26-0082

V.R. Marczyk and J.R. Wang comprehensively review the application of scRNA-seq to characterising tumour heterogeneity, dissecting the tumour microenvironment, & uncovering intratumor heterogeneity with potential therapeutic implications in PTC and ATC. 🔗 Read the review: doi.org/10.1530/ETJ-25-0141

Research impact goes beyond metrics - it advances scientific understanding, informs clinical practice & improves patient care. Explore our Highly Cited Collection, featuring 2024 articles that are shaping thyroidology: journals.bioscientifica.com/etj/pages/hi...

New research by Juan J Díez et al. compares levothyroxine treatment adequacy, response distribution, and determinants of inadequacy in a large real-world cohort applying the 2015 versus 2025 American Thyroid Association (ATA) criteria. Read the research: doi.org/10.1530/ETJ-...

New research by Tingting Hu et al. presents the first investigation of the association between thyroid indicators and pre-sarcopenic obesity, as well as its defining components, in a euthyroid cohort. 🔗 Read the research: doi.org/10.1530/ETJ-...

What is the real‑world clinical impact of molecular testing in advanced thyroid cancer? Read the latest research by Prashant Changoer et al. which evaluated the molecular landscape, clinical actionability & outcomes of matched therapy:🔗 doi.org/10.1530/ETJ-26-0074

A new retrospective case series by Liyona Kampel et al. explores the histopathologic changes induced by neoadjuvant therapies and their association with radiologic responses in patients with advanced DTC. 🔗 Read the research: doi.org/10.1530/ETJ-...

Should the UK adapt its newborn screening programme to detect central congenital hypothyroidism (CeCHT)? Catherine Peters et al. retrospectively evaluated 118 individuals with CeCHT, examining clinical characteristics, time to diagnosis & diagnostic pathways. 🔗 doi.org/10.1530/ETJ-26-0014

A new retrospective cohort study by Paulo Alonso Garcia Alves-Junior et al. investigates the relationship between sodium-iodide symporter (NIS) transcription and protein expression in pediatric differentiated thyroid carcinoma (DTC). Read the article: doi.org/10.1530/ETJ-...

We’re pleased to announce a new collection, 'Thyroid Disease and Pregnancy: Update on Diagnosis, Treatment and Outcomes', developed in collaboration with collection editors Associate Prof. Stine Linding Andersen, Prof. Onyebuchi Okosieme and Prof. Kris Gustave Poppe. 🔗 Learn more: bit.ly/4wu0T7w

Lenvatinib/pembrolizumab combined therapy is reimbursed in Italy for treatment of locally advanced, metastatic and/or recurrent ATCs. Given the lack of available real‑world data, E. Talpacci et al. conducted a retrospective study providing new real‑world efficacy data. 🔗 doi.org/10.1530/ETJ-25-0301

Could ketogenic metabolism offer a new therapeutic angle for anaplastic thyroid cancer (ATC)? A new study by Jiaqi Wang et al. shows that the ketone body acetoacetate suppresses ATC cell growth, migration and invasion, triggering cell‑cycle arrest via autophagy. 🔗 doi.org/10.1530/ETJ-...

New research by Samuel Frey et al. evaluates post‑operative MACEs & cardiac mortality in patients following total thyroidectomy for amiodarone‑induced thyrotoxicosis, comparing pre-operative left ventricular ejection fraction impairment & risk factors. 🔗 doi.org/10.1530/ETJ-25-0292

🤖 How reliable are AI chatbots when multiple management options are clinically reasonable? A study by Grigoris Effraimidis et al. compared endocrinologists' answers to clinical scenarios with outputs from 4 conversational AI models. Read the full article #OpenAccess: doi.org/10.1530/ETJ-25-0385

A new article by Joëlle Wiersema et al. reports on a global effort involving 2 rounds of quality‑control exchange among 5 labs with extensive experience in performing deiodinase assays, with the aim of improving the comparability of assay results across labs. 🔗 doi.org/10.1530/ETJ-26-0041

New research investigates the interference frequency affecting free thyroid hormone & TSH measurements using the Roche ECLIA, along with characterizing clinical features with various interference types, emphasising the importance of recognising interference patterns. 🔗 doi.org/10.1530/ETJ-25-0396

Amiodarone‑induced thyrotoxicosis (AIT) can be difficult to manage when standard therapies fail. A new case series reports four severe refractory AIT cases where therapeutic plasma exchange aided preparation for thyroidectomy, which restored euthyroidism. 🔗 doi.org/10.1530/ETJ-25-0351 #OpenAccess

🧠 Fatigue is a disabling symptom in Graves’ disease. A new article proposes that autoimmune‑driven inflammation may disrupt astrocyte function and neuronal signalling, contributing to the profound “brain fatigue” many patients report. Read more: doi.org/10.1530/ETJ-25-0172

Daniele Ceruti et al. evaluates 2 reference cohorts of patients with sporadic MTC treated at tertiary referral centres in 2 European countries - Italy, where routine CT measurement is included in diagnostic work‑up, & the Netherlands, where it's not. 🔗 doi.org/10.1530/ETJ-25-0381

A new review highlights the significant progress that has been made in the management of thyroid eye disease, attributed to the elucidation of important pathogenic mechanisms and the development of new therapeutics validated in randomised clinical trials. doi.org/10.1530/ETJ-25-0363