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European Virus Bioinformatics Center

@evbc.bsky.social

Bringing together the excellence of virology and bioinformatics. Tools: http://bit.ly/evbctools Impressum: https://evbc.uni-jena.de/impressum/

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European Virus Bioinformatics Center@evbc.bsky.social · last mo.

This comprehensive review synthesises current knowledge on the infection cycles of #Nucleocytoviricota (giant DNA viruses), highlighting shared mechanisms and lineage-specific innovations across diverse #virus families. 🦠🔬 📄 https://doi.org/10.1038/s41579-026-01319-6 👤 EVBC member: Mart Krupovic

Infection cycles of viruses of the phylum Nucleocytoviricota - Nature Reviews Microbiology

In this Review, Abergel et al. overview infection cycles across the Nucleocytoviricota phylum, highlighting shared mechanisms and lineage-specific features spanning viral entry, viral factory formation, genome replication, virion morphogenesis and egress, and discuss key unresolved questions in the field.

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European Virus Bioinformatics Center@evbc.bsky.social · last mo.

Large-scale analysis of #LassaVirus sequences reveals lineage-specific biophysical features and delivers comprehensive #glycoprotein structure catalogue, supporting vaccine and therapeutic development🦠🧬 📄 https://doi.org/10.1038/s44298-026-00196-3 👤 EVBC: Knut Reinert, Clara Schoeder, Denise Kühnert

Sequence to structure insights into Lassa virus population-level biophysical properties and glycoprotein structure catalogue - npj Viruses

npj Viruses - Sequence to structure insights into Lassa virus population-level biophysical properties and glycoprotein structure catalogue

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European Virus Bioinformatics Center@evbc.bsky.social · last mo.

Structure-based prediction of #phage proteins (Phage Homomer Level Estimate and Generation Method PHLEGM) uses #AlphaFold Multimer and interface scoring to resolve thousands of virus protein complexes from sequence data🧬💻 #StructuralBiology 📄 doi.org/10.64898/202... 👤EVBC: Robert Edwards, Bas Dutilh

Computational prediction resolves thousands of homooligomeric phage protein structures

Bacteriophages (phages) play essential roles in microbial systems, yet most phage proteins remain poorly characterised. Protein tertiary and quaternary structure information contributes valuable infor...

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European Virus Bioinformatics Center@evbc.bsky.social · last mo.

Event-triggered #MINFLUX #microscopy couples real-time confocal analysis with adaptive nanoscale imaging, enabling targeted capture of rare cellular events in 2D and 3D, such as during HIV-1 budding site formation 🦠🔬⚡#CellBiology 📄 https://doi.org/10.1038/s41467-026-73176-z 👤EVBC: Christian Eggeling

Smart event-triggered MINFLUX microscopy to catch and follow rare events - Nature Communications

Event-triggered MINFLUX combines confocal monitoring with real-time analysis to selectively acquire single-molecule data, enabling nanometre-resolution studies of membrane dynamics in living cells with improved speed, efficiency and data throughput.

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European Virus Bioinformatics Center@evbc.bsky.social · last mo.

A new open-access catalogue brings together all known human-infective RNA viruses, providing a valuable resource for virology, surveillance, and pandemic preparedness. 🦠📊 #Virology #InfectiousDiseases #OpenData 📄 https://doi.org/10.1038/s41597-026-07281-5 👤 EVBC member: Liam Brierley

A complete catalogue of human-infective RNA viruses - Scientific Data

Scientific Data - A complete catalogue of human-infective RNA viruses

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European Virus Bioinformatics Center@evbc.bsky.social · last mo.

Rfam database and R2DT workflows enable automated virus ncRNA annotation and API-driven retrieval of RNA families, alignments and structures for scalable RNA biology pipelines 🧬🧫📊 #RNA #Virology #Bioinformatics 📄 https://doi.org/10.64898/2026.05.10.724034 👤 EVBC members: Sandra Triebel, Manja Marz

Viral non-coding RNA structure annotation and API-based data retrieval with Rfam and R2DT

Rfam is a comprehensive database of non-coding RNA (ncRNA) families providing curated sequence alignments, consensus secondary structures, and covariance models for thousands of RNA families. The database is essential for identifying structured non-coding RNAs in newly sequenced genomes and understa...

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European Virus Bioinformatics Center@evbc.bsky.social · 2mo ago

#MachineLearning augmented #Raman spectroscopy enables accurate quantification of components in model #vaccine formulations, improving spectral deconvolution and compositional analysis in complex biological mixtures. 🧪📊🔬 📄 https://doi.org/10.1021/acs.analchem.5c05538 👤 EVBC member: Christel Kamp

Quantifying Components in a Model Vaccine with Machine-Learning-Augmented Raman Spectroscopy

Vaccination is a highly efficient strategy in controlling infections. Aluminum-containing adjuvants have long been used to enhance immunogenicity, but quantification of adsorbed antigens remains analytically challenging. This study uses Raman spectroscopy, a powerful, nondestructive technique, augme...

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European Virus Bioinformatics Center@evbc.bsky.social · 2mo ago

Researchers have created the first comprehensive catalogue of #bacteriophages in the honey bee gut #microbiome, providing new insights into #BeeHealth, microbial ecology and host–virus interactions. 🐝🦠 📄 https://doi.org/10.1038/s41467-026-72757-2 👤 EVBC members: Nikolas Basler, Jelle Matthijnssens

The honey bee triad: a comprehensive catalogue of phages in the Apis mellifera gut microbiome - Nature Communications

The gut microbiome of the honey bee is relatively simple, but its phages are not well studied. Here, Basler et al. use metagenomics to provide a comprehensive catalogue of honey bee gut phages across eight European countries, describing novel taxa as well as a core set of 97 prevalent phages.

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Global Virus Network@globalvirusnews.bsky.social · 2mo ago

A recent The New York Times article on treatment advances for the Bundibugyo #Ebola outbreak follows GVN's June 10 media briefing featuring Prof. Jean-Jacques Muyembe, Ebola research expert and Director of INRB. Read the article: https://ow.ly/rlTi50ZblRe #GlobalVirusNetwork #GVN #Ebola

Scientists Race to Test Treatments as Ebola Outbreak Widens

Trials are beginning on several drugs that have shown promise in preliminary studies against the virus that is causing the current outbreak.

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European Virus Bioinformatics Center@evbc.bsky.social · 3mo ago

ViBioM 2026 starts next week in Vilnius! We look forward to welcoming participants for talks, posters, and discussions in #virus #bioinformatics. Thanks to our sponsors GoVilnius, Viruses (MDPI), and @febsopenbio.bsky.social! #ViBioM2026 #openscience

International Virus Bioinformatics Meeting 2026 – EVBC

The International Virus Bioinformatics Meeting (ViBioM) is the pioneering conference that unites leading scientists at the intersection of virology and bioinformatics, fostering collaboration and innovation in the study of viruses. We are excited to invite you to join us for ViBioM 2026 in Vilnius,...

evbc.uni-jena.de

European Virus Bioinformatics Center@evbc.bsky.social · 3mo ago

Transcriptional mapping of #monkeypox virus in human epithelial cells reveals stage-specific gene expression and host interactions, improving our understanding of replication dynamics and potential targets for intervention. 🧬⚕️ 📄https://doi.org/10.1080/22221751.2026.2627079 👤EVBC: Cesare Gruber

Mapping transcriptional patterns of MPXV in human epithelial cells

The 2022 global outbreak of the monkeypox virus (MPXV) clade IIb highlighted changes in transmission dynamics, clinical features, and tissue tropism, yet the impact of host cell origin on viral tra...

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