Excited to share our lab’s latest preprint: In vivo single-cell CRISPR screening for microproteins identifies a critical ribosomal component. Check out how we systematically explore #microprotein functions and how they expand the cellular proteome!
Our genome encodes > 7000 microproteins that have been previously ignored in genome annotations. How do these microproteins impact tissue function? Here, we use an in vivo single-cell CRISPR screen to systematically explore microprotein function in the mouse epidermis. 1/9