Why do some cranial sutures fuse too early? New FaceBase data point to timing: FGFR2 signaling normally declines after birth, dialing down retinoic acid to keep the coronal suture open. Overactivate it and the suture closes. RNA-Seq, Chai lab, USC. @ccmb.usc.edu www.facebase.org/2026/08/04/r...

How do continuously growing teeth withstand constant mechanical load? New FaceBase data identify a KDM6B–BMI1–PIEZO1 "mechanostat" that shields incisor progenitors from stress-induced apoptosis. Bulk RNA-seq + Cut&Run-seq, Chai lab, USC. www.facebase.org/2026/07/30/r...

It's that time again! Join us for our Office Hours tomorrow: 📅 Wednesday, July 29, 1 pm ET / 10 am PT Zoom with FaceBase team members and ask questions about finding data, submitting data, citing data, and more things data! Click here to register: usc.zoom.us/meeting/regi...

Save the date! The 2027 FaceBase Community Forum heads to Los Angeles — April 27–28, 2027, at USC/ISI in Marina del Rey. Details soon: bit.ly/FBForum2027

New on FaceBase: single-cell RNA-seq data from a knock-in mouse model reveals how amelogenin phosphorylation shapes enamel organ biology — including 5.1-fold downregulation of Shh in secretory ameloblasts. Explore the dataset from Beniash/Margolis, Univ of Pittsburgh: doi.org/10.25550/AF-...

We've extended the poster abstract deadline for the 2026 FaceBase Annual Meeting! Share your work and connect with the craniofacial research community. Deadline is now: Friday, April 24. Submit here → facebase.org/community/annual-meeting/2026-facebase-annual/abstracts/

New on FaceBase 🧬 Xu, Liu & Jiang (Cincinnati Children's) contribute Six2 and CTCF ChIP-seq datasets from wildtype mouse embryonic facial tissues (E10.5–E13.5), shedding light on the regulatory landscape of craniofacial morphogenesis. doi.org/10.25550/7Z-...

📋 A few days left to submit a poster abstract for the 2026 FaceBase Annual Meeting! Share your work and connect with the craniofacial research community. Deadline: Friday, April 17. Submit here → facebase.org/community/annual-meeting/2026-facebase-annual/abstracts/

New on FaceBase 🧬 A new dataset from Ma & Rosin examines how prenatal depletion of CSF1R+ macrophages and osteoclasts disrupts craniofacial development — with effects on the skull, mandible, palate, ear ossicles, and more. Dataset + publication now available. www.facebase.org/2026/04/09/r...

Will you be at AADOCR/IADR or GRC next week? FaceBase will be in Ventura and San Diego with demos, presentations, and opportunities to connect with our team. See where to find us! www.facebase.org/2026/03/19/f...

FACEBASE COMMUNITY FORUM 🗓 Abstract Deadline for Talk Consideration - This Friday, March 20! Submissions will remain open after this first deadline. This deadline only applies to abstracts that would like to be considered for a talk. Submit abstract ➡️ www.facebase.org/community/an...

New data: Spatial transcriptomics (using seqFISH) reveals a fibroblast-immune microenvironment remodeling pathway in CFA-induced TMJ arthritis in mice. PI: Jian-Fu Chen (University of Southern California) doi.org/10.25550/8Q-...

It's that time again! Join us for our Office Hours this week: 📅 Wednesday, Feb 25, 1 pm ET / 10 am PT Zoom with FaceBase team members and ask questions about finding data, submitting data, citing data, and more things data! Click here to register: usc.zoom.us/meeting/regi...

New data: microCT datasets from ameloblast-specific Smad4 knockout and Ambn-IRESCre mice. Using a novel ameloblast-restricted Cre line, these data reveal severe enamel-specific pathology and highlight Ambn-IRESCre as a powerful tool for enamel gene function studies: www.facebase.org/2026/02/11/r...

Registration and Call for Abstracts are open for the FaceBase 2026 Community Forum! Advances in data reuse, integration, and AI-ready biomedical research in dental, oral, craniofacial, inner ear and related research. 📅 May 4-5, 2026 📍 Arlington, VA (also via Zoom) Register: bit.ly/FBForum2026

New data release: Justin Cotney’s lab - @justincotney.bsky.social - generated a single-nucleus RNA sequencing (snRNA-seq) atlas of critical time points during human and mouse craniofacial development, now openly available through FaceBase. Read all about it here: www.facebase.org/2026/01/20/r...

Save the dates for the next FaceBase Community Forum: May 4 & 5 2026 in Arlington, VA. More details coming soon! www.facebase.org/community/an...

Missed the FaceBase Bootcamp? No worries! Catch up with recordings and slides covering data discovery, submissions, and DMS plans: 🎥 www.facebase.org/community/tr... #FaceBase #DataSharing #CraniofacialResearch #NIH #DentalResearch #DataReuse #FAIRdata #DataScience

Reminder: 📣 Our next virtual bootcamp, tailored for both users and data contributors, is coming up on Wednesday, November 5th! For dental, oral, and craniofacial researchers, clinicians and students: www.facebase.org/community/tr...

It's that time again! Join us for our Office Hours tomorrow (Wednesday), 1 pm ET / 10 am PT! Talk with FaceBase team members and ask questions about finding data, submitting data, citing data, and more! Click here to register: usc.zoom.us/meeting/regi...

📣 Our next virtual bootcamp, tailored for both users and data contributors, is coming up next week: Wednesday, November 5th! Whether you're a seasoned user of FaceBase or looking to contribute data for the first time, this event is for you! www.facebase.org/community/tr...

🎉 Congratulations to FaceBase PI, Yang Chai, on his confirmation as Dean of the USC Ostrow School of Dentistry!! @ccmb.usc.edu

The University of Southern California@usc.edu · 10mo ago

This week we officially welcomed Dr. Yang Chai as dean of the Herman Ostrow School of Dentistry—renowned scientist, visionary leader, and Trojan through and through.

New release on #FaceBase: Timothy C. Cox’s lab - @craniofacialprof.bsky.social - has identified SHROOM3 as a bona fide craniofacial microsomia gene. The mouse embryo imaging data from this study is now openly available through FaceBase. Read all about it here: www.facebase.org/2025/09/15/r...

If you are attending the poster session at the Society for Craniofacial Genetics and Developmental Biology meeting this year, make sure to stop by and say hi to Rob and Alejandro at the FaceBase poster and demo! @scgdb.bsky.social

We're excited to announce a new article about FaceBase at the Node! Check it out!

the Node@the-node.bsky.social · 11mo ago

Featured resource: Facebase In this post, we learn about the data and functionalities available at Facebase @facebase.bsky.social, and hear about new initiatives they are developing. thenode.biologists.com/featured-res...

Join us for our Office Hours tomorrow (Wednesday)! 1-2 pm Eastern / 10-11 am Pacific Meet with FaceBase team members and ask questions about finding data, submitting data, citing data and more! We can also help you fill out your DMS plans! Click here to register: usc.zoom.us/meeting/regi...

Welcome! You are invited to join a meeting: FaceBase Office Hours. After registering, you will receive a confirmation email about joining the meeting.

Welcome! You are invited to join a meeting: FaceBase Office Hours. After registering, you will receive a confirmation email about joining the meeting.

usc.zoom.us

New releases on #FaceBase: two global orofacial-cleft datasets (OFC1/OFC2) + two Appalachian oral-health-disparity cohorts (COHRA1 & 2). Rich 3-D imaging, genomics & longitudinal surveys ready for discovery. Read all about it here: www.facebase.org/2025/07/28/r...

It's that time again for FaceBase Office Hours! This Wednesday (tomorrow!) 1pm Eastern / 10 am Pacific! Meet with FaceBase team members and ask questions about finding data, submitting data, citing data and more! Click here to register on Zoom: usc.zoom.us/meeting/regi...

It’s been 25 years since the UCSC Genome Browser launched. Nature profiles how the website remains an essential tool for navigating the genome and understanding its structure, function, and clinical impact. #Academicsky 🧬 🧪

’We couldn’t live without it’: the UCSC Genome Browser turns 25

After a quarter of a century, the website remains an essential tool for navigating the genome and understanding its structure, function and clinical impact.

go.nature.com

Slides, webcasts and posters from the 2025 FaceBase Community Forum are now available on facebase.org. Topics: new collaborations, data integration, AI applications, integrating clinical elements into FaceBase, new technologies, advances in basic research and more! www.facebase.org/community/an...