@fewill26.bsky.social
Because these international grocers need your support now more than ever, especially during these times, here’s a guide to the international grocers of the Twin Cities that I wrote for @racketmn.com: racketmn.com/guide-intern...
A Guide to the International Grocers of the Twin Cities - Racket
The Twin Cities is home to over 40 international grocers, and they deserve your dollars, too.
racketmn.com
UMN epigenetics flashtalk competition is underway! Full room to cheer on our trainees! Great idea by Natalia Tretyakova from @umnmedchem.bsky.social @umnchemistry.bsky.social
Research Corp is amazing. So grateful for the support of this research and my students! @umnchemistry.bsky.social
RCSA has awarded $800,000 to 11 #CottrellScholars through its RCSA Bridge Awards, an emergency initiative to help stabilize strong research programs that have experienced disruptions due to abrupt changes to their federal funding.
Excited about this work. Lots of cool potential directions
Exciting @biorxivpreprint.bsky.social by the group of Gunda Georg. They developed a tissue-specific PROTAC that recruits the E3 ligase scaffolding protein MAGEA11 that is highly expressed in many cancers and otherwise only in sperm and placenta. www.biorxiv.org/cont... #TPD #ChemSky #ChemBio
PhD defense day is always a great time to celebrate student accomplishments (awesome job Dr Cole Scholtz) and nab a new group pic!
Call for papers for a new special issue on covalent modulators. Consider submitting to ACS Med. Chem. Lett, J. Med. Chem. or ACS Chem. Biol.! pubs.acs.org/page/si/cova...
Exploring Covalent Modulators in Drug Discovery and Chemical Biology
pubs.acs.org
Got mine. Get 'em while they last
Bioorganic GRC is set! I got tired of the lack of swag so made a couple of unofficial tees. Order one if you want to support the conference (or simply enjoy strange looks in grocery stores). Spirit: chembio-shop.fourthwall.com/products/grc... World Tour: chembio-shop.fourthwall.com/products/spi...
Dont' forget to register for the 2025 Portoghese Lectureship Webinar on June 12th! web.cvent.com/event/668f0f...
Everyone in the past was neurotypical, which is how we got things like this single-author, eight-volume encyclopedia of ferns
ACS MEDI degrader/induced proximity webinar about to start. Don't miss out!
This was a great collaboration with our UMN chemistry team and @mayoclinic.org collaborators, including Vijay Shah ad Harmeet Malhi @umnchemistry.bsky.social
And its finally out! Check out my recent article investigating the role of BRD4 in inflammation. But what excites me the most: we explore the safety side of things, and reduce the risk of BET side effects by >50 fold through more selective molecules. pubs.acs.org/doi/10.1021/... #chemsky
Hey #chemsky , just saw February's NIH Advisory council was finally rescheduled for May 22. I found this very heartening news.
What are work retreats good for? Registering your first start up. Excited to take the plunge with Vijay Shah and Harmeet Malhi @mayoclinic.org for our LLC, BromoThera
Interesting read on the funding decline for medicinal chemistr projects. Might also help if JACS would support publishing more high impact med chem papers versus sending to J. Med. Chem. pubs.acs.org/doi/10.1021/...
Evaluation of the Recent Dynamics for Funding Medicinal Chemistry Projects in Academia. Results of a Survey Conducted by IUPAC Division VII (Chemistry and Human Health)
Data collected from scholars across twenty-three countries over the past decade (2010–2019) reveals a 40% decrease in financial support for medicinal chemistry projects. The decline is especially notable among projects focused on small organic molecules. This drop in grants indicates a troubling trend that could jeopardize future drug development by undermining research in this crucial field. The reduction in funding not only affects ongoing research but also threatens the education and training of future medicinal chemists, potentially leading to a shortage of skilled professionals in the pharmaceutical industry. To counteract this negative trend, it is imperative for funding agencies, the pharmaceutical sector, and government bodies to take immediate action. Strengthening financial support is essential to sustain innovation in drug development and ensure the continued advancement of medicinal chemistry as a vital academic and practical discipline.
pubs.acs.org
After a month of prep work, just received the news that the my NIH study section is cancelled for tomorrow. My heart goes out to all of the PIs who are waiting on the news for their proposals. This is also very unsettling for NIH funding in general
Check out the newest virtual special issue at ACS Med Chem Lett and J. Med. Chem. highlighting the many faces of medicinal chemistry! pubs.acs.org/page/si/many... Editorial from Ashley Adams, Lori Ferrins, and Anna Junker @pubs.acs.org
Many Faces of Medicinal Chemistry
Published research on topics of current scientific interest.
pubs.acs.org
A thoughtful summary of what was glaringly absent from the recent NIH notice
🧪⚛️ Here is a writeup about how university research works in the US, how indirect costs figure into this, what is going on and what the consequences may be. nanoscale.blogspot.com/2025/02/indi...
“The impact of the collective executive orders and directives appears devastating.” scim.ag/40ureTO
Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring
Researchers facing
scim.ag
I finished up my NIH study sectionreviews today. I do this 3 times a year and it takes me about 3-4 weeks of part time effort. Im proud of this work, as it helps make the scientific enterprise better, amplifying good ideas, while providing critical feedback to others to make their science better.
For Chemical Biologists and Medicinal Chemists thinking about an engaging GRC-checkout the line-up for : www.grc.org/high-through... Chaired by @briandna.bsky.social and Deb Rothman. Still spots left for the GRC and GRS!
2025 High Throughput Chemistry and Chemical Biology Conference GRC
The 2025 Gordon Research Conference on High Throughput Chemistry and Chemical Biology will be held in New London, New Hampshire. Apply today to reserve your spot.
grc.org
Only a few days left, and only a few seats left - do not miss this exceptional PSL Chemical Biology Symposium in Paris, with a fantastic lineup - Register now!!! We will be happy to meet you there - Deadline January 31st!!! www.pslchembiol.com
Paris, 27 - 28 February 2025
pslchembiol.com
VERITAC-2 primary endpoint data collection is on Jan 31 this week. Could be quite a milestone day for the PROTAC community!
#NIH #medsky #scisky #researchsky #cdc #hhs #biosky #chemsky #4thReich The losses we’re experiencing right now… he’s destroying years and years, possibly decades of work in some cases www.cnn.com/2025/01/24/h...
Scientists at NIH can’t purchase supplies for their studies after Trump administration pauses outside communications | CNN
Scientists at the National Institutes of Health have been told the communications pause announced by the Trump Administration earlier this week includes a pause on all purchasing, including supplies f...
cnn.com
I have been preparing a course called "Writing Like a Chemist" and finally taught the first class today! Looking forward to the semester. I am supporting the class with the book "Write Like a Chemist" which I highly recommend.
“I don’t consider myself COVID cautious. I consider myself COVID competent,” Zebrowski said. “Cautious would imply that I have an unreasonable fear of something. I do not have an unreasonable fear of this disease.” Nailed it 🔥
Meet the Americans who still take COVID-19 precautions seriously
People with immune system health problems continue to take precautions against COVID-19 five years into the pandemic.
apnews.com
Congrats to all of you out there who submitted your MIRA renewals. Treat yourself tonight!
Love it. Gamefying PROTACs. Check this out in J chem ed. pubs.acs.org/doi/10.1021/...
DEGRADATOR: A Gaming Expedition Into Targeted Protein Degradation Therapies
In an era of rapid scientific advancement, the need for engaging educational tools is critical. DEGRADATOR, a 2D computer game, bridges this gap by immersing players in the ubiquitin-proteasome system...
pubs.acs.org