Prof Fergal O’Brien

@fjobrien.bsky.social

Bioengineer, sports fan, dad to twins | RCSI DVC of Research & Innovation | AMBER Centre & RCSI TERG PI | ERC PI | Member RIA

Well done to Juan Carlos Palomeque and the whole interdisciplinary team involved in the study. Grateful to all funders particularly @researchireland.ie @AMBERCentre.bsky.social who funded Juan Carlos's PhD thesis carried out under the supervision of @sbrowne4.bsky.social Cathal Kearney & I.

Prof Fergal O’Brien@fjobrien.bsky.social · 6mo ago

Our latest @tissueengdublin.bsky.social paper in Bioactive Materials on a new #bioactive #biomaterial for #woundhealing showing how scaffold-mediated miRNA-155 inhibition promotes regenerative macrophage polarisation to direct chronic wound healing. www.sciencedirect.com/science/arti...

A multidisciplinary team effort led by @taramcguire.bsky.social as part of her @researchireland.ie @ambercentre.bsky.social & IRFU Charitable Trust funded PhD. Thanks to everyone involved particularly our #PPI advisory panel of clinicians & injured players living with spinal cord injury.

Prof Fergal O’Brien@fjobrien.bsky.social · 7mo ago

Our latest publication in Bioactive Materials showing how scaffold based #genedelivery can be applied to #spinalcord with a PTEN-siRNA activated scaffold promoting axonal regrowth www.sciencedirect.com/science/arti...

RNA therapeutics may have potential to treat complex conditions such as #osteoarthritis. In this article in Nature Nanotechnology, Claudio Intini & I descibe the prospects in the field & highlight a recent article by Dewani et al which shows the potential of this area www.nature.com/articles/s41...

Lesion-targeted, severity-responsive nanoparticle delivery for RNA therapy in osteoarthritis - Nature Nanotechnology

Matrix-INverse Targeting (MINT) nanoparticles harness cartilage changes to deliver RNA therapies, reducing degeneration and pain in osteoarthritis.

nature.com

Tomorrow! Join us tomorrow November 13th in the old Science Gallery in @tcddublin.bsky.social from 6-8pm to see the animated short 'Something's Missing' from TERG and 'Quantum Quest' from TCD with an introduction from @fjobrien.bsky.social

AMBER Centre @ambercentre.bsky.social · 10mo ago

AMBER's #ScienceWeek Event: "Smalltalk on the Big Screen" 📆13th November 6pm – 8pm 📌Old Science Gallery @tcddublin Accessible + inclusive event for all ages Free but tickets are limited! Register: www.eventbrite.ie/e/smalltalk-... #scienceweek25 #materialsscience #bioengineering

Really exciting times ahead and look forward to welcoming everyone to RCSI to experience our new public engagement space! #Humanarium

RCSI University of Medicine and Health Sciences@rcsi.bsky.social · 10mo ago

RCSI is delighted to launch #Humanarium, a new free exhibition space dedicated to health and well-being! Our first exhibition, Heart: More than a Beat, will open in February ❤️ We can't wait to welcome you! Learn more: www.humanarium.ie #UNSDG3

Vibrant orange and pink gradient background with blurred human face. White text in the center reads 'Humanarium RCSI' with 'coming soon' below it.

Looking forward to opening the #MyHealthRCSI ‘Rethinking Asthma’ event this evening. More information in today’s Irish Times. New thinking on asthma management may be a game-changer www.irishtimes.com/health/your-...

New thinking on asthma management may be a game-changer

Fundamental changes in asthma management are all geared to breaking the inhalers-antibiotics-inhalers-steroids cycle

irishtimes.com

RCSI University of Medicine and Health Sciences@rcsi.bsky.social · 11mo ago

There are limited spaces available for tomorrow’s #MyHealthRCSI discussion on ‘Rethinking Asthma’🚵‍️ Taking place from 6-7:30pm, this free in-person event will explore self-management of asthma, how to prevent asthma attacks and new treatments. 🔗 www.rcsi.com/dublin/news-... Supported by Presidio

The contributions from our #PPI panel including Ciaran McCarthy were essential to this research. We are grateful to the IRFU Charitable Trust & @researchireland.ie for funding this project. @rcsi-research.bsky.social advanced.onlinelibrary.wiley.com/doi/full/10....

advanced.onlinelibrary.wiley.com

Prof Fergal O’Brien@fjobrien.bsky.social · last yr.

Great example of research that would not have occurred without the unique interdisciplinary environment of @ambercentre.bsky.social A real team effort between @tissueengdublin.bsky.social researchers led by research fellow Ian Woods and 2D materials scientists from Prof Valeria Nicolosi’s lab.

Great example of research that would not have occurred without the unique interdisciplinary environment of @ambercentre.bsky.social A real team effort between @tissueengdublin.bsky.social researchers led by research fellow Ian Woods and 2D materials scientists from Prof Valeria Nicolosi’s lab.

AMBER Centre @ambercentre.bsky.social · last yr.

Interdisciplinary AMBER research team @rcsi.bsky.social & @tcddublin.bsky.social develop 3-D printed implant to deliver electrical stimulation to injured areas of spinal cord offering new route to repair nerve damage 👉 ambercentre.ie/amber-resear... #advancedmaterials #bioengineering

Publication in Advanced Science from Dr Ian Woods on the development of spatially-organised electroconductive neurotrophic scaffolds for repair of neurotrauma! Facilitated by joint funding from the Research Ireland AMBER Centre and the IRFU Charitable Trust, read the press release and paper below!

RCSI University of Medicine and Health Sciences@rcsi.bsky.social · last yr.

An implant developed by RCSI and @ambercentre.bsky.social researchers has been shown to deliver electrical stimulation to injured areas of the spinal cord. The study, in partnership with the IFRU-CT, offers a potential new route to repair nerve damage. ➡️ www.rcsi.com/dublin/news-... #RCSIdiscover

Congratulations to Professor Andreas Heise, RCSI Department of Chemistry and collaborator Professor Matthew Gibson on their success in this EPSRC-Research Ireland programme. Their research will investigate the prevention of ice formation where sub-zero temperatures are present. #RCSIdiscover

Research Ireland@researchireland.ie · last yr.

€4.95 million in funding has been announced to support joint research and technology development projects in Ireland and the United Kingdom through the EPSRC-Research Ireland Joint Funding of Research Programme. Read here: www.researchireland.ie/news/epsrc/ @ukri.org

Man working on a computer