Cian O'Connor speaking this week at the SMA European Congress about how biomimetic viscoelastic hydrogels promote motor neuron outgrowth and modulate astrocyte behaviour for Spinal Muscular Atrophy regeneration applications! This work is kindly supported by the SMA Foundation. @fjobrien.bsky.social
Prof Fergal O’Brien
@fjobrien.bsky.social
Bioengineer, sports fan, dad to twins | RCSI DVC of Research & Innovation | AMBER Centre & RCSI TERG PI | ERC PI | Member RIA
We were delighted to welcome Taoiseach Micheál Martin and Minister James Lawless to our labs yesterday for the opening of 118 St Stephen's Green, where the Taoiseach spoke with spinal cord injury activist and TERG PPI collaborator Ciaran McCarthy and head of TERG @fjobrien.bsky.social
Well done to Juan Carlos Palomeque and the whole interdisciplinary team involved in the study. Grateful to all funders particularly @researchireland.ie @AMBERCentre.bsky.social who funded Juan Carlos's PhD thesis carried out under the supervision of @sbrowne4.bsky.social Cathal Kearney & I.
Our latest @tissueengdublin.bsky.social paper in Bioactive Materials on a new #bioactive #biomaterial for #woundhealing showing how scaffold-mediated miRNA-155 inhibition promotes regenerative macrophage polarisation to direct chronic wound healing. www.sciencedirect.com/science/arti...
Our latest @tissueengdublin.bsky.social paper in Bioactive Materials on a new #bioactive #biomaterial for #woundhealing showing how scaffold-mediated miRNA-155 inhibition promotes regenerative macrophage polarisation to direct chronic wound healing. www.sciencedirect.com/science/arti...
Scaffold-mediated miRNA-155 inhibition promotes regenerative macrophage polarisation leading to anti-inflammatory, angiogenic and neurogenic responses for wound healing
Chronic wounds represent a significant clinical challenge due to persistent inflammation and impaired nerve regeneration that delay healing. Conventio…
sciencedirect.com
A multidisciplinary team effort led by @taramcguire.bsky.social as part of her @researchireland.ie @ambercentre.bsky.social & IRFU Charitable Trust funded PhD. Thanks to everyone involved particularly our #PPI advisory panel of clinicians & injured players living with spinal cord injury.
Our latest publication in Bioactive Materials showing how scaffold based #genedelivery can be applied to #spinalcord with a PTEN-siRNA activated scaffold promoting axonal regrowth www.sciencedirect.com/science/arti...
Our latest publication in Bioactive Materials showing how scaffold based #genedelivery can be applied to #spinalcord with a PTEN-siRNA activated scaffold promoting axonal regrowth www.sciencedirect.com/science/arti...
Development of a PTEN-siRNA activated scaffold to promote axonal regrowth following spinal cord injury
sciencedirect.com
Got a minute to spare? Why not give TERG's latest piece in #NatureNanotechnology a read! www.nature.com/articles/s41... @fjobrien.bsky.social @rcsi.bsky.social @rcsi-research.bsky.social
Lesion-targeted, severity-responsive nanoparticle delivery for RNA therapy in osteoarthritis - Nature Nanotechnology
Matrix-INverse Targeting (MINT) nanoparticles harness cartilage changes to deliver RNA therapies, reducing degeneration and pain in osteoarthritis.
nature.com
Delighted to see this publication from our @ambercentre.bsky.social collaboration with Integra LifeSciences which shows how laser treatment of natural polymers can be used to tailor site-specific degradation, controlled vascularization & enhanced tissue repair. doi.org/10.1016/j.ac...
Redirecting
doi.org
Lovely weekend at @bini-irl.bsky.social conference. Superb plenary talks by Molly Stevens & Haughton Lecturer Michael Walsh. Well done to @tissueengdublin.bsky.social team for excellent presentations including prize winners Aamena Mejevdiwala, Eavan Pakenham & Joshua Pepper! #BinI2026 #TERGonTour
RNA therapeutics may have potential to treat complex conditions such as #osteoarthritis. In this article in Nature Nanotechnology, Claudio Intini & I descibe the prospects in the field & highlight a recent article by Dewani et al which shows the potential of this area www.nature.com/articles/s41...
Lesion-targeted, severity-responsive nanoparticle delivery for RNA therapy in osteoarthritis - Nature Nanotechnology
Matrix-INverse Targeting (MINT) nanoparticles harness cartilage changes to deliver RNA therapies, reducing degeneration and pain in osteoarthritis.
nature.com
Great to have Prof Anthony Windebank in @rcsi.bsky.social today to discuss our IRFU Charitable Trust @ambercentre.bsky.social @tissueengdublin.bsky.social collaboration with Mayo Clinic on biomaterials for spinal cord injury.
Well done to @researchireland.ie for developing this ARC hub program. These hubs will be unique & really exciting enablers of innovation in Ireland. Very pleased to be involved both from @rcsi.bsky.social institutional and @tissueengdublin.bsky.social & @ambercentre.bsky.social PI perspective.
The ARC Hub programme seeks to drive regional development by turning the novel, cutting-edge research carried out in Irish universities into market-ready commercial opportunities. Read about the ARC Hub programme in @irishtimes.com today: www.irishtimes.com/sponsored/20...
Congratulations to Matthew and thanks to Fabio Quondamatteo and Ed Sander for taking the time to examine Matthew's PhD thesis. We are grateful to the @researchireland.ie @ambercentre.bsky.social for funding this project.
Congratulations to Matthew McGrath on passing his viva today! Matthew's PhD research focused on development of biomimetic multi-layered antimicrobial scaffolds for enhanced wound healing. Thank you to examiners Fabio Quondamatteo and Ed Sander! Supervisors @fjobrien.bsky.social and Shane Browne
Tomorrow! Join us tomorrow November 13th in the old Science Gallery in @tcddublin.bsky.social from 6-8pm to see the animated short 'Something's Missing' from TERG and 'Quantum Quest' from TCD with an introduction from @fjobrien.bsky.social
AMBER's #ScienceWeek Event: "Smalltalk on the Big Screen" 📆13th November 6pm – 8pm 📌Old Science Gallery @tcddublin Accessible + inclusive event for all ages Free but tickets are limited! Register: www.eventbrite.ie/e/smalltalk-... #scienceweek25 #materialsscience #bioengineering
Lovely evening at the @RCSI School of Postgraduate Studies Awards & Black Jacket ceremony for record intake of >150 new doctoral students. Delighted to welcome in particular our new group of @tissueengdublin.bsky.social PhD students!
Really exciting times ahead and look forward to welcoming everyone to RCSI to experience our new public engagement space! #Humanarium
RCSI is delighted to launch #Humanarium, a new free exhibition space dedicated to health and well-being! Our first exhibition, Heart: More than a Beat, will open in February ❤️ We can't wait to welcome you! Learn more: www.humanarium.ie #UNSDG3
During my visit to China, I also got back to beautiful Suzhou to meet research MSc students in our International College of Pharmaceutical Innovation partnership program between @rcsi.bsky.social and Soochow University.
Just back from Wuhan and TERMIS Asia Pacific conference with our @tissueengdublin.bsky.social team #TERGonTour
Looking forward to opening the #MyHealthRCSI ‘Rethinking Asthma’ event this evening. More information in today’s Irish Times. New thinking on asthma management may be a game-changer www.irishtimes.com/health/your-...
New thinking on asthma management may be a game-changer
Fundamental changes in asthma management are all geared to breaking the inhalers-antibiotics-inhalers-steroids cycle
irishtimes.com
There are limited spaces available for tomorrow’s #MyHealthRCSI discussion on ‘Rethinking Asthma’🚵️ Taking place from 6-7:30pm, this free in-person event will explore self-management of asthma, how to prevent asthma attacks and new treatments. 🔗 www.rcsi.com/dublin/news-... Supported by Presidio
Great to have our latest paper published in Biomaterials on tissue engineering strategies for peridontal & endodontic regeneration. A really nice collaboration between @tissueengdublin.bsky.social & our dental colleagues. authors.elsevier.com/sd/article/S...
In today’s @irishtimes.com, RCSI’s Head of EDI, Liz Hughes explores the progress made by Irish HEIs in equality, diversity and inclusion and calls for a wider protection of human rights: www.irishtimes.com/ireland/educ...
Irish universities should have no tariffs on talent
Decades of reform and cultural change have made our colleges European leaders in gender equality and diversity – but the work of protecting rights continues
irishtimes.com
A great first day at the International Congress on Biomaterials for Wound Healing for the TERG team yesterday! #ICBWH2025 @fjobrien.bsky.social @markodobricic.bsky.social @rcsi.bsky.social
The contributions from our #PPI panel including Ciaran McCarthy were essential to this research. We are grateful to the IRFU Charitable Trust & @researchireland.ie for funding this project. @rcsi-research.bsky.social advanced.onlinelibrary.wiley.com/doi/full/10....
advanced.onlinelibrary.wiley.com
Great example of research that would not have occurred without the unique interdisciplinary environment of @ambercentre.bsky.social A real team effort between @tissueengdublin.bsky.social researchers led by research fellow Ian Woods and 2D materials scientists from Prof Valeria Nicolosi’s lab.
Great example of research that would not have occurred without the unique interdisciplinary environment of @ambercentre.bsky.social A real team effort between @tissueengdublin.bsky.social researchers led by research fellow Ian Woods and 2D materials scientists from Prof Valeria Nicolosi’s lab.
Interdisciplinary AMBER research team @rcsi.bsky.social & @tcddublin.bsky.social develop 3-D printed implant to deliver electrical stimulation to injured areas of spinal cord offering new route to repair nerve damage 👉 ambercentre.ie/amber-resear... #advancedmaterials #bioengineering
Publication in Advanced Science from Dr Ian Woods on the development of spatially-organised electroconductive neurotrophic scaffolds for repair of neurotrauma! Facilitated by joint funding from the Research Ireland AMBER Centre and the IRFU Charitable Trust, read the press release and paper below!
An implant developed by RCSI and @ambercentre.bsky.social researchers has been shown to deliver electrical stimulation to injured areas of the spinal cord. The study, in partnership with the IFRU-CT, offers a potential new route to repair nerve damage. ➡️ www.rcsi.com/dublin/news-... #RCSIdiscover
An implant developed by RCSI and @ambercentre.bsky.social researchers has been shown to deliver electrical stimulation to injured areas of the spinal cord. The study, in partnership with the IFRU-CT, offers a potential new route to repair nerve damage. ➡️ www.rcsi.com/dublin/news-... #RCSIdiscover
RCSI researchers develop 3D printed implant to help repair spinal cord injuries
A research team at RCSI has developed a 3D printed implant to deliver electrical stimulation to injured areas of the spinal cord. More ...
rcsi.com
Great to see this published. Well done to Claudio Intini, Michael Joyce and everyone involved in the project - in particular Pieter Brama & his team in UCD School of Veterinary Medicine. Latest output from our @erc.europa.eu funded #ReCaP project. @rcsi-research.bsky.social
New paper from TERG published in the International Journal of Biological Macromolecules today on the use of biomimetic reinforced scaffolds in combination with a novel suturing technique for large articular cartilage defects! Read it now: www.sciencedirect.com/science/arti... @fjobrien.bsky.social
Delighted to welcome @garryduffy.bsky.social back to RCSI & as new Prof. of Anatomy in Dept. of Anatomy & Regen Med. He brings a wealth of research experience in advanced biomaterials and medical technologies and his work is a great addition to @tissueengdublin.bsky.social. Exciting times ahead.
Professor Garry Duffy has been appointed as RCSI's 30th Professor of Anatomy and Head of the Department of Anatomy and Regenerative Medicine. His appointment supports our focus on integrating health sciences education with innovative, patient-centred research. More ➡️ www.rcsi.com/dublin/news-...
Congratulations to the 344 new doctors who celebrated at our #RCSIConferring yesterday 🎓 RCSI’s School of Medicine class of 2025 came together with friends and family to celebrate their achievements. Read more about the conferring ceremony here: tinyurl.com/3bbbn3tn
Congratulations to Professor Andreas Heise, RCSI Department of Chemistry and collaborator Professor Matthew Gibson on their success in this EPSRC-Research Ireland programme. Their research will investigate the prevention of ice formation where sub-zero temperatures are present. #RCSIdiscover
€4.95 million in funding has been announced to support joint research and technology development projects in Ireland and the United Kingdom through the EPSRC-Research Ireland Joint Funding of Research Programme. Read here: www.researchireland.ie/news/epsrc/ @ukri.org