What if EV diversity starts long before vesicles are released? Our new work identifies TSPAN3 as a marker of a distinct secretory MVB population with unique trafficking and EV cargo, providing a new framework for understanding EV heterogeneity. Read here: www.biorxiv.org/content/10.6...

TSPAN3 defines a distinct intracellular trafficking route to secretory multivesicular bodies https://www.biorxiv.org/content/10.64898/2026.08.26.747209v1