Mercredi 5 aout, c'est au tour de Marie de nous raconter guerre et paix chez les bactéries: Café Chez Ernest, 18H
Frédérique Le Roux
@fredoleroux.bsky.social
Professeure/chaire d'excellence du Canada Université de Montréal Département de microbiologie, infectiologie et immunologie What do I like? Wild things 😜 yet phages are my favorite!
Mercredi prochain, 18h, cafe chez Ernest, l'estivale du Cinq a Science continue
Après la Coupe du monde de foot, place à la tournée du @cinqascience.bsky.social au café Chez Ernest ! Les conférences reprendront tous les mercredis à partir de 18 h (22 juillet-26 aout) : 🍻 30 minutes de présentation 💬 30 minutes de discussion autour d’un verre
So happy to host my old friend Delphine Destoumieux-Garzón for our One Health & Climate Change workshop at the Faculty of Medicine, Université de Montréal. Very inspiring work carried out by her and her colleagues! #Udem #OneHealth #climatechange
Want to join us for Social Viruses in Vancouver this summer? One week to go until we start looking at applications (May 7th). To apply: socialviruses.zoology.ubc.ca #socialviruses #evosky #lovevirology #virosky
Asher Leeks@asherleeks.bsky.social · 4mo agoThe Social Lives of Viruses is coming to Vancouver, Canada, from 4th-8th August 2026! This is a free meeting dedicated to all aspects of virus-virus interactions & evolution. To apply: socialviruses.zoology.ubc.ca @sociovirology.bsky.social #socialviruses #evosky #lovevirology #virosky
Cinq à Science goes summer mode ☀️ Join us at Chez Ernest (Saint-Hubert Street) every Wednesday from July 22 to August 26. 🕕 Talks at 6 PM — a friendly space to promote microbiology, make science accessible, and spark discussions over a drink!
Le Cinq à Science passe en mode estival ☀️ Rendez-vous au Chez Ernest (rue Saint-Hubert) tous les mercredis du 22 juillet au 26 août. 🕕 Conférences à 18h — une occasion conviviale de promouvoir la science en microbiologie, la rendre accessible et en discuter autour d’un verre !
The Social Lives of Viruses is coming to Vancouver, Canada, from 4th-8th August 2026! This is a free meeting dedicated to all aspects of virus-virus interactions & evolution. To apply: socialviruses.zoology.ubc.ca @sociovirology.bsky.social #socialviruses #evosky #lovevirology #virosky
Excited to share our new paper out today in @science.org 🎉 We show that HGT via natural competence drives diversification of chromosomal integrons in V. cholerae 🤩 Below a 🧵 on key findings incl. background on natural competence in V. cholerae 1/ #microsky #phagesky www.science.org/doi/10.1126/...
science.org
>1000 lytic vibriophages sequenced. 4 years later… still there. Same genomes. Same vibes. Different story. When nothing changes—but everything does. Congrats to Jeff & Karine et al. and @epcrocha.bsky.social for the intellectual turbulence ;-) www.nature.com/articles/s41...
Finally, oysters serve as hotspots of horizontal gene transfer betw bacteria, mediated by mobile genetic elements. Which, considering the high density of bacteria in marine animals (rel. environment), could be quite general. Great work led by Jeff Liang, Karine Cahier. With @fredoleroux.bsky.social
Our ms on re-sampling 4 years apart vibrio phage in natural environments is now out with some improvements. First, clearer evidence of cryptic population dynamics between phage and vibrio, presumably because of genetic diversity. www.nature.com/articles/s41...
Complex temporal dynamics of phage-bacteria populations in an animal-associated marine system - Nature Communications
It remains unclear how viral genomes remain relatively stable over time, given the rapid co-evolution seen within hosts. Here, authors explore complex marine phage-bacteria dynamics using over 1000 ph...
nature.com
Latest from the lab! Between clinical S. aureus, most gene transfer mechanisms are blocked, yet lateral transduction remains highly efficient. Restriction modification-defective strains act as gateways for horizontal gene transfer, enabling DNA flow across populations. rdcu.be/fbNQK
Immune-deficient bacteria serve as gateways to genetic exchange and microbial evolution
Nature Communications - The efficiency of horizontal gene transfer between different bacterial lineages is often unclear. Here, Figueroa et al. show that lateral transduction is the primary driver...
rdcu.be
Lundi 9 mars, 12H, évènement CERC Le Roux/decanat UdeM, journée internationale de la femme. Projection documentaire et débat "sur la libération de la parole et de l'écoute de personnes ayant vécu de l’oppression basée sur le genre." Pavillon Jean-Brillant – Salle B-0245 . Inscription avant 2 mars.
Seeking expressions of interest from researchers abroad for a Canada Impact+ Research Chair ($1M/year × 8 + up to $6M CFI) in AI-enabled antibiotic discovery and/or AMR, phage & phage-based derivatives. Email me a short vision, CV, and 3–5 key papers. Deadline: March 10, 2026 (Intake 2: June 15).
🦠💊 L’Institut @pasteur.fr vient de publier un communiqué de presse sur nos récents travaux, qui décrivent une nouvelle piste pour augmenter l’efficacité des antibiotiques. #Pasteurdon #Recherche #Science #AMR Merci à toutes celles et ceux qui ont contribué. 📘 English version coming soon!
Une piste prometteuse pour augmenter l’efficacité des antibiotiques
Les aminosides sont des antibiotiques efficaces contre de très nombreuses bactéries telles que Escherichia coli, Pseudomonas aeruginosa ou Staphylococcus aureus. Mais jusqu’à présent, personne ne sava...
pasteur.fr
Many thanks to all those involved, including Jeffrey Liang, who stayed in our lab for several months, our own Charles Bernard and, of course, @fredoleroux.bsky.social and the usual suspects @agencerecherche.bsky.social @erc.europa.eu @cnrsbiologie.bsky.social @pasteur.fr @umontreal.ca etc
Two intensive sampling periods of oyster-associated vibrio and their phage, 4 years apart, and many surprises. Despite being washed by the Atlantic, wide tides, and vibrio (almost?) disappearing most of the year, we can find the exact same virulent phages 4 years later (down to 0 SNP)! preprint👇
Frédérique Le Roux@fredoleroux.bsky.social · 10mo agoPhages evolve fast, or do they? In oysters, some stay identical for years. With >1,200 phages & 600 Vibrio genomes, we reveal long-term stability and new mobile elements. Proud of this collaborative work across our teams (Roscoff-UdeM and @epcrocha.bsky.social www.biorxiv.org/cgi/content/...
Phages evolve fast, or do they? In oysters, some stay identical for years. With >1,200 phages & 600 Vibrio genomes, we reveal long-term stability and new mobile elements. Proud of this collaborative work across our teams (Roscoff-UdeM and @epcrocha.bsky.social www.biorxiv.org/cgi/content/...
Ecological constraints foster both extreme viral-host lineage stability and mobile element diversity in a marine community
Phages are typically viewed as very rapidly evolving biological entities. Little is known, however, about whether and how phages can establish long-term genetic stability. We addressed this eco-evolut...
biorxiv.org
Thrilled to share our two latest papers with the @tcostalab.bsky.social lab! In the first, we uncover a new mechanism of satellite transfer: cf-PICIs hijack tails from diverse phages to spread across species. @imperialcollegeldn.bsky.social www.cell.com/cell/fulltex...
Chimeric infective particles expand species boundaries in phage-inducible chromosomal island mobilization
Capsid-forming PICIs (cf-PICIs) produce their own capsids and exploit phage tails from unrelated species to transfer their DNA across bacterial hosts. This tail piracy enables broad dissemination and ...
cell.com
Chimeric infective particles expand species boundaries in phage-inducible chromosomal island mobilization: Cell www.cell.com/cell/fulltex...
Chimeric infective particles expand species boundaries in phage-inducible chromosomal island mobilization
Capsid-forming PICIs (cf-PICIs) produce their own capsids and exploit phage tails from unrelated species to transfer their DNA across bacterial hosts. This tail piracy enables broad dissemination and ...
cell.com
The ecology and evolution of microbial immune systems: a look on the wild vibrio side Phil. Trans. R. Soc. B by @fredoleroux.bsky.social royalsocietypublishing.org/doi/10.1098/...
The ecology and evolution of microbial immune systems: a look on the wild vibrio side | Philosophical Transactions of the Royal Society B: Biological Sciences
Natural populations of vibrio beyond the well-studied pandemic strains of Vibrio cholerae, provide a powerful model for investigating the eco-evolutionary dynamics of microbial immune systems. Their genetic diversity, ecological versatility, ease of ...
royalsocietypublishing.org
👉 Next stop: Montréal! 🇨🇦 Thrilled to join the Canada Society of Microbiology (CSM) conference, June 17-20. Science, community, and reconnecting with old friends — can’t wait!
The study involves our microbiologist @fredoleroux.bsky.social, whom we profiled in late 2023 as a new hire and Canada Excellence in Research Chair: nouvelles.umontreal.ca/en/article/2...
How do we minimize the use of antibiotics?
New to UdeM and flush with an $8M, federally funded research chair, microbiologist Frédérique Le Roux looks to solve the problem of infectious diseases of bacterial origin in farmed marine species.
nouvelles.umontreal.ca
Institut Pasteur | 130 years of biomedical research@pasteur.fr · last yr.🧬 Bacteria fight both antibiotics and viruses with the same genetic tool: integrons! New study (Institut Pasteur, CNRS, Université Paris Cité & Montréal): ~10% of gene cassettes may defend against phages. 🛠️ One step closer to smarter therapies. 🔗 www.pasteur.fr/en/research-...
Allo Montreal, 11 juin –18H au café La brassée: "Des sphères aux spirales, des extrémophiles aux probiotiques: plongez dans l’univers fascinant des bactéries ! " Appéro- Science, qui dit mieux? #cinqascience #5ascience
And I've written a few reviews on the subject over the years, but this one is pretty short, so why not start there ;) www.sciencedirect.com/science/arti...
How clonal are bacteria over time?
Bacteria and archaea reproduce clonally (vertical descent), but exchange genes by recombination (horizontal transfer). Recombination allows adaptive m…
sciencedirect.com