Hot off the biorxiv press! 🔥 Samuel Lara-Reyna finds GBP5 enhances macrophage glycolysis via glucose uptake, GTPase activity dependent and as being cis-Golgi localised. Bonus finding, GBP5 is important for full M1 macrophage functionality. www.biorxiv.org/content/10.6...

Check out this new paper by @avishenoy.bsky.social lab - GBP1 can detect extracellular bacteria from the inside of cells! 😎 LPS solubilisation, Toxoplasma vacuole disruption and now immunity through actin binding - what a superpower protein! 😬 Happy to have supported this project!

Avinash Shenoy@avishenoy.bsky.social · 10mo ago

📢A new effector-triggered immunity role for GBP1! No place for pathogens to hide now that GBP1 can detect extracellular pathogens that hijack the actin cytoskeleton. Surprise*suprise* GBP1 does this independently of LPS! 🧵 biorxiv.org/content/10.1...

🔥 Open postdoc position in human inflammation-driven control of infection! 🔥 Join me at the University of Geneva, Switzerland this summer as I’m moving my Wellcome-funded research activity to the Department of Microbiology and Molecular Medicine! (1/5) Please share!

Read this important piece about child loss due to under researched genetic mutations that stole @criminographer.bsky.social Alexander and Isabelle. www.thetimes.com/uk/healthcar...

Two years after our toddler’s sudden death, our world collapsed again

When Emily Cooper’s son died aged three, tests showed she and her husband had a genetic mutation endangering their other children

thetimes.com

Tune into #inflammazoom in 45min!

Seth Masters@sethlucianmasters.bsky.social · 2y ago

Looks like a great inflammazoom coming up Dec 16 with @inflammasomelab.bsky.social and Si Ming Man! These talks are great for everyone interested in autoinflammation. Register here to access the live session as well as on-demand talks from past sessions: events.abcam.com/AnYVL?rt=Qlp...

I’m liking the new energy on this platform. I’ve sat on the scientific sidelines for some of this year, while we as a family are re-grouping after losing Leo aged 4 in ‘22 and Alby aged 1 month in ‘23. I’m grateful for so many supportive colleagues out there. Science is a wonderful place.