Frank Santoriello

@fsantoriello.bsky.social

Microbial geneticist 🧬🧫| Princeton MolBio Postdoc with Bonnie Bassler Artist 🎨🖊️ | I like to draw bacteria and dead things Likes loud music, sci-fi/fantasy/horror, tattoos, and fermented foods. he/him https://www.franksantorielloart.com

New short story from my postdoc in the Bassler lab is up on bioRxiv! Turns out our favorite quorum sensing responsive phage VP882 is a member of a larger family of phages that is distributed across multiple bacterial species and can eavesdrop on a universally conserved autoinducer. #PhageSky 🦠🧫

bioRxiv Microbiology@biorxiv-microbiol.bsky.social · last yr.

A family of linear plasmid phages that detect a quorum-sensing autoinducer exists in multiple bacterial species https://www.biorxiv.org/content/10.1101/2025.07.30.667625v1

Happy to share our work that's now online in Nature Microbiology: Gamma-Mobile-Trio systems are mobile elements rich in bacterial defensive and offensive tools. If you're interested in Anti-phage, T6SS, Vibrio, or MGE then this is for you. 🦠 rdcu.be/dXMwQ

Gamma-Mobile-Trio systems are mobile elements rich in bacterial defensive and offensive tools

Nature Microbiology - GMT-containing genomic islands in Vibrio parahaemolyticus and other diverse bacteria serve as a stockpile of immune and anti-phage defence systems, antibiotic-resistance genes...

rdcu.be

New preprint from my postdoc with Bonnie Bassler! We show that phage VP882 responds to different host factors depending on the environmental context of the infected host, highlighting the need to study phage-bacteria interactions in relevant contexts to get the full picture. #MicroSky 🦠

Diagram of the quorum-sensing-dependent lifestyle decisions of vibriophage VP882.
bioRxiv Microbiology@biorxiv-microbiol.bsky.social · 2y ago

The LuxO-OpaR quorum-sensing cascade differentially controls Vibriophage VP882 lysis-lysogeny decision making in liquid and on surfaces https://www.biorxiv.org/content/10.1101/2024.04.02.587679v1

Evil Dead Rise is the wildest version of white people shit in the franchise so far. In the first movie they find the Necronomicon in a basement. Easy mistake. In this one they find it in a tomb covered in medallions under 1000 hanging crucifixes inside a sealed bank vault. What could go wrong?