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Flavio Zolessi

@fzolessi.bsky.social

Associate Professor of Cell Biology, Facultad de Ciencias, Udelar, Uruguay. PI, Cell Biology of Neural Development group. #development #retina #neurulation #zebrafish Member of IBRO-LARC @ibroorg.bsky.social

57 Posts524 Follower563 Folgt
Flavio Zolessi@fzolessi.bsky.social · last mo.

New preprint! Another piece from @gaparicio.bsky.social thesis, now exploring the role of PALS1 (aka Nok, or MPP5) in lamination and photoreceptor progenitors positioning in the developing zebrafish retina and retinal organoids: tinyurl.com/yya754tf

Reduction of PALS1/Nok disrupts retinal lamination through altered cell positioning while preserving photoreceptor self-organization capacity

The vertebrate neural retina is composed of several neuronal types that precisely organize into layers, with photoreceptors facing the outer surface and the projection neurons, retinal ganglion cells,...

tinyurl.com

DORA@dorassessment.bsky.social · 3mo ago

Rethinking assessment isn’t easy, especially in contexts shaped by global inequalities. In Uruguay, a growing movement is challenging metric‑driven systems and opening space for more inclusive and socially relevant research assessment. New blogpost by Natalia Gras & Judith Sutz 👉 bit.ly/RRA-Uruguay

Graphic announcing a new guest blog post on research evaluation reform in Uruguay, highlighting how metric-driven systems have shaped academic life and how collective efforts are creating change.Quote highlighting that, for the first time in Uruguay, universities, research institutes, and national organizations are collaborating to rethink research evaluation; guest blog post by Natalia Gras and Judith Sutz.Call-to-action graphic inviting readers to explore the full story and rethink what is valued in research, with link to the Uruguay research assessment blog post.
Justin Kumar@flyeyelab.bsky.social · 5mo ago

The 2026 Visual System Development GRC and GRS are fast approaching. Jeremy Kay, Kristen Kwan, Robert Johnston, and I have built an exciting program that we hope you will enjoy. Looking forward to seeing everyone at the meeting this summer in beautiful Maine. Register and RT!

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Dr. Brittany J. Carr@drbjcarr.bsky.social · 5mo ago

I made this to demonstrate that for data visualization it's not only the color scheme, but the colors chosen for each channel, that matter. Here is the same image of rods and cones represented in RGB and simulated color blindness, showing how small changes can make a huge difference in what you see.

An image of a frog retina with photoreceptor labeling. The same image is shown 6 times in different colors. In the far left image, the small cones are difficult to detect in both the RGB and the color-blind simulated version. The middle image is the best representation of the data for fully sighted and color blind people, since the cones are easy to detect for both. The image on the right is better than the image on the far left to see the cones in RGB, but is still not color blind friendly.
Flavio Zolessi@fzolessi.bsky.social · 5mo ago

Published in final version in @cellsdev.bsky.social: "Mechanical conditions preventing live cell extrusion during primary neurulation in amniotes" doi.org/10.1016/j.cd... Find a full description in the thread about the preprint @biorxivpreprint.bsky.social: bsky.app/profile/fzol...

Flavio Zolessi@fzolessi.bsky.social · 12mo ago

Preprint alert! Just from the oven, the adventures of a young theoretical biophysicist (Santi Bosch) in a usually strictly wet lab (BCDN): how is it that extreme forces in amniotes primary neurulation do not break the highly dynamic neuroepithelium apart? www.biorxiv.org/content/10.1...

SEBD@sebioldev.bsky.social · 10mo ago

The importance of model organisms for research and training www.nature.com/articles/s41...

Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology

As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.

nature.com