GadelhaLab
@gadelhalab.bsky.social
Molecular cell biologist leading a research group at the University of Nottingham, UK. This account is managed by the lab postdocs.
Gene fitness isn't simply essential or non-essential; it has magnitude & timing. Our latest preprint introduces DRiF-Seq for quantitative functional #genomics in disease-relevant #Trypanosoma brucei: new biology and a resource for the community. Comments welcome! www.biorxiv.org/content/10.6...
Conference talks? Easy. A soapbox in the middle of town? Much harder. 😅 Thankfully the questions came quickly and the conversations were fantastic. Outreach matters: today's curious child may be tomorrow's scientist. #WomenInSTEM @uonresearch.bsky.social @uniofnottingham.bsky.social
This weekend women scientists and engineers from @uniofnottingham.bsky.social y.social will take to Speakers' Corner to share exciting talks and debates on all things #STEM. Full story here tinyurl.com/yck99yx6 #SciComm #WomenInSTEM #SoapboxScience #PublicEngagement
An outstanding week at the Gordon Research Conference on Host-Pathogen Interactions at beautiful Salve Regina overlooking the Atlantic. Fantastic science, open discussions, and a truly collegiate atmosphere. Privileged to see so much exciting work before it reaches the journals. #GRC #HostPathogen
Happy 100th birthday to the living legend and national treasure that is Sir David Attenborough. Few figures alive have done as much for nature and conservation as Sir David, and we've been very lucky to work with him over the years. #DavidAttenborough #Attenborough100 #Nature #PlanetEarth
Happy 100th birthday to Sir David Attenborough. His work has helped to bring science to millions of people around the world, and we’ve been lucky enough to welcome him to the Crick over the years to share his passion and enthusiasm with us.
Today is the International Day of Women and Girls in Science (11th February). A moment to recognize those who were once told they had no place in science. www.un.org/en/observanc...
International Day of Women and Girls in Science | United Nations
The purpose of the day is to achieve full and equal access to and participation in science for women and girls.
un.org
Not only did Mendeleev organise what we knew at the time, he also left space for what we didn’t yet know (but he predicted to exist).
The Royal Society@royalsociety.org · 6mo agoDmitri Mendeleev was born #OnThisDay in 1834. He was a Russian chemist and inventor who formulated the Periodic Law and created the earliest example of a periodic table. He was elected a Foreign Member of the Royal Society in 1892, and won both our Davy and Copley Medals.
Today is World NTD Day www.who.int/news/item/27...
World Health Assembly adopts decision to recognize 30 January as World NTD Day
Today, delegates participating in the virtual Seventy-fourth World Health Assembly endorsed a decision recognizing 30 January as World Neglected Tropical Diseases Day (‘World NTD Day’). Partners first...
who.int
Drugs for Neglected Diseases initiative (DNDi)@dndi.org · 6mo ago📢 Today is #WorldNTDDay! Over 1B people are affected by neglected tropical diseases. Too many still lack safe & effective treatments. 👉 Share this post to support science, innovation & global health funding. #EndTheNeglect #BeatNTDs #UniteActEliminate
As a Fellow of Newnham College (2010-12) and proud alumna, this video resonated deeply with Cat. Newnham’s founding commitment (to enable women’s education when it was denied) still matters profoundly today.
The Royal Society@royalsociety.org · 6mo agoBorn #OnThisDay in 1885 was Marjory Stephenson FRS, biochemist and one of the first two women to be elected to the Royal Society. Stephenson also founded the Microbiology Society and served as its second president. #HistoryOfScience #WomenInSTEM www.youtube.com/watch?v=hr5b...
Join Sir Michael Ferguson FRS for the Leeuwenhoek Prize Lecture on 26 January 2026, as he explores how science can provide opportunities to make better, safer medicines and diagnostics for neglected infectious diseases. Register now: https://bit.ly/4j9U58P
We’re excited to share our review: "Next-generation genetic screens in kinetoplastids", now published in NAR! It covers a range of perturbation methods—from RNAi to prime editing—as well as emerging assay technologies like scRNA-seq and image-activated cell sorting. academic.oup.com/nar/article/...
Next generation genetic screens in kinetoplastids
Abstract. The genomes of all organisms encode diverse functional elements, including thousands of genes and essential noncoding regions for gene regulation
academic.oup.com
Check out our latest study on the PfRIPR protein, essential for the malaria parasite to get inside our blood cells. We show how antibodies block the function of PfRIPR by preventing its flexible hinges from bending, or by stopping it from compacting as part of its mechanism.
If you assume GPI insertion signals = surface destination, trypanosomes disagree. Tom’s work shows GPI-anchored protein sorting occurs independently of GPI insertion signals, hinting at alternative sorting logic at the parasite surface. tinyurl.com/gpi-anchor #MembraneBiology #CellSurface
Sorting of GPI-anchored proteins at the trypanosome surface is independent of GPI insertion signals
The segregation of glycosylphosphatidylinositol-anchored proteins (GPI-APs) to distinct domains on the plasma membrane of eukaryotic cells is importan…
tinyurl.com
🧬 Fancy a fully funded PhD at the cutting edge of parasitology? 🦠✨ We’re recruiting outstanding students to join an exciting 4-year, fully funded PhD programme in Molecular & Cellular Parasitology – home & international students welcome 🌍
🦠 Grad students & postdocs in parasitology: Apply now for the Biology of Parasitism (BoP): Modern Approaches course at @MBLScience. Hands-on labs, expert lectures, and cutting-edge tools. 📅 Summer 2026 | ⏰ Deadline Feb 5 🔗 mbl.edu/courses
Brazil, Australia and Italy have the highest satisfaction scores in Nature’s global 2025 PhD survey. A Nature Careers article examines what makes earning a doctorate in these countries different. #Academicsky 🧪
Are these the happiest PhD students in the world?
Brazil, Australia and Italy have the highest satisfaction scores in Nature’s global 2025 PhD survey — but are these nations really the best places to do a doctorate?
go.nature.com
The Leeuwenhoek Medal and Lecture 2025 is awarded to Professor Sir Mike Ferguson CBE FMedSci FRS for major contributions in discovery science and application to the treatment of neglected infectious diseases. #RSMedals https://royalsociety.org/medals-and-prizes/leeuwenhoek-lecture/
The United Kingdom as seen from the International Space Station. -Credits: NASA
Great opportunity for a Research Assistant to join us on a project involving genomics and big-data analysis in molecular & cellular parasitology. Apply by 10 July: jobrxiv.org/job/universi... Interviews: 18 July #ScienceJobs #CellBiology #MolecularBiology
Research Assistant/Senior Technical Specialist
Post a job in 3min, or find thousands of job offers like this one at jobRxiv!
jobrxiv.org
Good news all round: Cat is promoted to principal investigator. The Cell Surface has its first IF released=6.2! And we are recruiting another research assistant to join the team and work on DRiF-Seq projects. Apply [here] (jobs.nottingham.ac.uk/vacancy.aspx...) until 10 July; interviews 18 July.
Job Vacancy at the University of Nottingham: Senior Technical Specialist (fixed-term)
Applications are invited for a full-time Senior Technical Specialist position in the laboratories of Catarina Gadelha and Bill Wickstead, to join a programme of research on key aspects of African tryp...
jobs.nottingham.ac.uk
Really stimulating week in the South of France, working with colleagues at the forefront of host-pathogen cell biology research: @sergemostowylab.bsky.social , Sandrine Bourdoulous, Jean-Christophe Paillart, Matteo Bonazzi, Pierre Diamante, Patricia Bassereau and Nathalie Chazal.
We really enjoyed the Royal Society team’s visit to the lab this morning, to mark Majeed’s first year in his Career Development fellowship. The scheme is running for the second time, and hopefully a third round will open in September 2025. #STEM #science #postdocs #fellowships @royalsociety.org
Mark Carrington’s symposium: the combination of intellectual stimulation from the scientific content and the joy of reconnecting with colleagues and friends made the day a memorable and enjoyable one for all participants, and specially for Mark! #parasites @cambridgeuni.bsky.social
It is a great honour to invite you to a symposium to celebrate the career of Mark Carrington. An exciting set of talks, particularly if you are fascinated by trypanosomes.
Being cartographers of parasite surfaces, at the molecular, functional and fitness levels, we’ve enjoyed reading this series of papers on data collection to atlas integration and beyond. Check it out: @humancellatlas.bsky.social @natureportfolio.bsky.social www.nature.com/immersive/d4...
The Human Cell Atlas: towards a first draft atlas
In a collection of research articles and related content, the Human Cell Atlas consortium presents tools, data and ideas towards the generation of their first draft atlas of cells in the human body.
nature.com
Majeed and Cat are enjoying the Career Development Fellowship welcome event at the Royal Society – 3 days of science talks, networking workshop, library tours, video interviews and delicious vegetarian meals. A fantastic start for a 4-year postdoctoral fellowship.
Congratulations to Majeed! Last October, he was awarded a Royal Society Career Development Fellowship to decode the mechanism of antigenic variation in Trypanosoma vivax in the lab. Expect great developments soon! royalsociety.org/news/2024/09...
Outstanding researchers named in first cohort of Royal Society Career Development Fellowship pilots | Royal Society
Eight researchers exploring topics from ageing-related cancers, to radiation-proof glass and the birth of planets.
royalsociety.org
