1/ Per the recent @qedscience.bsky.social discussions, I’m wondering how ppl think about principled consistency in evaluating selection-based criteria in science. E.g., any accomplishment that involves outcompeting other ppl (grad school admissions, publishing, grant apps, awards/fellowships, etc)
Mike Gallagher
@geneticsmike7.bsky.social
Geneticist and stem cell biologist studying epigenetics and neurodegeneration at Whitehead Institute and MIT.
1/ Happy to share important work done with my co-author Andrew Khalil in the labs of Rudolf Jaenisch @whiteheadinstitute.bsky.social @mit.edu and David Mooney @harvard.edu @wyssinstitute.bsky.social trying to assess and fix the major problem of transgene silencing in human ESC/iPSC based work
Tomorrow @ 8am #AAIC2025 I'll present work on genetic risk mechanisms in #MS #AD using #CRISPR screens in #microglia. Come see poster as well until 4:30! Co-led by @xochitl-luna.bsky.social, Jaenisch/Corradin labs @whiteheadinstitute.bsky.social. Link to paper: www.medrxiv.org/content/10.1...
Functional genomic dissection of MS risk loci reveals convergence of cis and trans gene regulatory mechanisms in microglia
Neurological diseases (NDs) are a major source of unmet medical need, and translational insights have been hampered by complex underlying pathophysiologies and limitations of experimental models. Nonc...
medrxiv.org
1/ I'd like to share a major part of my postdoctoral work, co-led by @xochitl-luna.bsky.social of Olivia Corradin's lab, and co-supervised by my postdoc advisors Rudolf Jaenisch and Rick Young @whiteheadinstitute.bsky.social @mit.edu. We wanted to see if #iPSC could be used to systematically study
To all those receiving layoff notices from the Trump-Musk Admin, know that we stand with you and are working with our legal partners and in Congress to fight back and right these wrongs. If you want to report what you're seeing or experiencing, you can share your story here:
Share how President Trump’s Executive Orders are impacting you or your family | U.S. Senator Chris Van Hollen of Maryland
The Official U.S. Senate website of Senator Chris Van Hollen of Maryland
vanhollen.senate.gov
The Democrats on the House Science Committee have set up a website to collect stories from fired federal employees, anonymously if desired democrats-science.house.gov/sciencefirings
Were you fired by President Trump? | House Committee on Science, Space and Technology
The House Committee on Science, Space and Technology
democrats-science.house.gov
Pls sign and share!
Petition to Reverse the NIH Indirect Cost Cap initiated by Tom Maniatis. Please amplify Sign the Petition: chng.it/kK2HMP5pGk "Share with Leadership & Faculty. Reach out to professional societies, biotech and pharma leaders, and philanthropic organizations to raise awareness and mobilize support."
Everyone who cares about science, medicine, healthcare and patients, please sign this and give money if you can.
Petition to Reverse the NIH Indirect Cost Cap initiated by Tom Maniatis. Please amplify Sign the Petition: chng.it/kK2HMP5pGk "Share with Leadership & Faculty. Reach out to professional societies, biotech and pharma leaders, and philanthropic organizations to raise awareness and mobilize support."
Linde Jacobs’s mother died after a genetic mutation gradually laid waste to her brain. Now the same gene is coming for her own mind. Can she find a way to stop it?
A Woman With a Rare Gene Mutation Fights to Avoid Her Mother’s Fate
A mutant gene is coming to steal Linde Jacobs’s mind. Can she find a way to stop it?
nytimes.com
Linde Jacobs and everyone else fighting for cures for rare diseases are incredible, and they need our help.
Glad to be here. I'm a postdoc @whiteheadinstitute.bsky.social @mitofficial.bsky.social in the labs of Rudolf Jaenisch and Rick Young, using iPSC models of neurons and glia to better understand their role in health and disease.