Gergo Porkolab
@gergoporkolab.bsky.social
Research Fellow at the Campbell Lab @tcddublin.bsky.social studying signaling pathways that regulate blood vessels in the brain ---- Previously @BarriersGroup, Szeged, Hungary
Excited to see the full program for GRS 'Barriers of the CNS' 2026 now live! www.grc.org/barriers-of-... It’s been a pleasure putting this together with @sidaraydin.bsky.social, with the help of @dwwilliamslab.bsky.social and Joe Nicolazzo. Hope to see you there!
2026 Barriers of the CNS (GRS) Seminar GRC
The 2026 Gordon Research Seminar on Barriers of the CNS (GRS) will be held in New London, New Hampshire. Apply today to reserve your spot.
grc.org
Happy to share our new preprint on BBB mechanobiology on bioRxiv: www.biorxiv.org/cgi/content/... We describe an exciting new link between tight junctions and cell-matrix adhesions during BBB maturation and in epileptic BBB dysfunction.
Endothelial tight junctions and cell-matrix adhesions reciprocally control blood-brain barrier integrity
Brain endothelial cells (ECs) rely on mechanical cues to provide a physical barrier that protects the brain. Yet how ECs integrate forces to establish and maintain the blood-brain barrier (BBB) remain...
biorxiv.org
fluidsbarrierscns.biomedcentral.com/articles/10....
Proteome profile differences among human, monkey, and mouse brain microvessels and cultured brain microvascular endothelial cells - Fluids and Barriers of the CNS
Background The blood-brain barrier (BBB) expresses transporters, receptors, and tight junction proteins that regulate the exchange of substances between the blood and brain. The differences in the exp...
fluidsbarrierscns.biomedcentral.com
New paper led by Avril Reddy in @mattcampbelltcd.bsky.social lab showing IPS derived human RPE cells expressing aflibercept and/or soluble CD59 can attenuate lesions in mouse model of age-related macular degeneration. Cool project to help out with. www.cell.com/molecular-th...
Enhanced retinal pigment epithelial cells as a delivery vehicle for retinal disease
Age-related macular degeneration (AMD) is one of the leading causes of central retinal blindness. Here, Campbell and colleagues show that transplanted retinal pigment epithelial cells can be engineere...
cell.com