Giulia Guidi

@giulsguidi.bsky.social

Cornell CS Assistant Prof | LBNL Affiliate Faculty | UC Berkeley PhD | ALPS Lab | Dogs, Skis, Pottery | Kotlikoff MUST RESIGN. https://giuliaguidi.github.io/

I'll be presenting Mikado, which performs genotype matrix multiplication directly on compressed genotype graphs using either CPUs and GPUs. With Mikado, we can achieve order-of-magnitude speedups for PCA and BOLT-LMM-inf over PLINK2-based analyses!

New preprint from our collaborators @giulsguidi.bsky.social, and her PhD students Yifan Li and Qingyao Sun, which enabled GRG-based statistical genetics across different computer architecture๐Ÿ”ฅ. So the practical win for GRG users: you can pick the matvec backend to best leverage your machine &task.

Sparse Linear Algebra Accelerates Genotype Representation Graph Computation at Biobank Scale

Biobank-scale genomic analyses are increasingly constrained by computational costs, as hundreds of thousands to millions of samples and variants must be analyzed together. The genotype representation ...

biorxiv.org