***New preprint from the lab*** showing “Generative replay across hippocampal-neocortical circuits”. In sleep we show spiking sequences in V1 (sensory neocortex!) that represent information that has not been directly experienced www.biorxiv.org/content/10.6... @bndu.ox.ac.uk @ndcnoxford.bsky.social

Generative replay across hippocampal-neocortical circuits

To make flexible decisions, the brain needs to make inferences between events that were not directly experienced together. In sharp-wave ripple (SWR) events, during periods of rest and sleep, spiking ...

biorxiv.org

New perspective paper from our lab: “The hippocampus as a generative model” out now !! royalsocietypublishing.org/rstb/article... The traditional view of the hippocampus is that it creates a cognitive map. Here we extend this view to conceptualise the hippocampus as a “generative model”.

The hippocampus as a generative model

Abstract. A generative model can be defined as a model of the latent causes of sensory input that can be used to generate new data samples. By examining em

royalsocietypublishing.org

Interested in human replay and solid methods? Jointly with @skjerns.de we're releasing a benchmark dataset with known ground-truth neural sequences in MEG & fMRI, for developing & validating replay methods. First test: existing methods show similar effect sizes, but room to improve shorturl.at/6TgIr

FASTIMAGES: Validating replay detection methods in human neuroimaging using a combined MEG and fMRI dataset

Studies in rodents and humans using invasive electrophysiology have established that neural replay is a ubiquitous phenomenon in the brain that is associated with a wide range of cognitive functions, ...

shorturl.at

Oxford, the longest running continuous weather station in UK history, with temperature observations stretching back to 1815, has preliminarily broken its maximum temperature record for May yesterday by OVER 3ºC with a temperature of 33.7ºC. Unprecedented in its 211-year history.

Now in eLife as a reviewed preprint too elifesciences.org/reviewed-pre...

Leonie Glitz@glitzleonie.bsky.social · 6mo ago

Interested in cognitive maps? Wondering how you should best train your participants? Luckily for you, we have investigated just that! Very excited to share a preprint from my PhD in which we show how initial training curriculum affects the cognitive maps we form osf.io/preprints/ps... [1/6]

*** New paper from the lab in Nature Comms !! *** “Noradrenaline causes a spread of association in the hippocampal cognitive map” by the amazing @reneecabbage.bsky.social in collab. w labs of Jill O’Reilly, Will Clarke, and modeling from Prakriti Parthasarathy and @tpvogels.bsky.social, see below!

Renée Koolschijn@reneecabbage.bsky.social · 5mo ago

Very pleased to share that our study “Noradrenaline causes a spread of association in the hippocampal cognitive map” is out in @natcomms.nature.com (my final PhD paper, only 3.5 years post PhD! 🙃) Find the paper here: www.nature.com/articles/s41...

Interested in cognitive maps? Wondering how you should best train your participants? Luckily for you, we have investigated just that! Very excited to share a preprint from my PhD in which we show how initial training curriculum affects the cognitive maps we form osf.io/preprints/ps... [1/6]

** We have up to TWO funded PhD positions available in our lab!! Apply below to find new ways to enhance memory👇 Pls retweet ** Deadline: 2nd December 1. Cross-species closed-loopTMR: tinyurl.com/bddu4tp6 2. TUS and TMR in humans: tinyurl.com/jjws5ctj Happy to chat to interested applicants.

Are you planning to attend #CCN2025? Do you want to reflect on how to direct your skills and aptitudes to tackle today's most pressing social problems? Make sure you come to Amsterdam a day early to attend our satellite event on Science for Social Good. Register here: forms.gle/TFRCZYX2qfwD...

CCN for social good - satellite registration

See https://anneurai.net/2025/05/05/ccn-for-social-good-2025-satellite-event/ for more information

forms.gle

Feel like doing some really exciting mouse work with a fantastic PI in Oxford? Come join our lab!!

Helen Barron@helencbarron.bsky.social · last yr.

*** Come join us !! We are recruiting !! *** How does the brain generate beliefs that go beyond direct experience? How do these mechanisms go awry in psychosis? The Barron lab tinyurl.com/bdf4drjf @MRCBNDU @NDCNOxford are recruiting a new postdoc tinyurl.com/ut4vbwt4 to work in mouse models

🧠✨How do we rebuild our memories? In our new study, we show that hippocampal ripples kickstart a coordinated expansion of cortical activity that helps reconstruct past experiences. We recorded iEEG from patients during memory retrieval... and found something really cool 👇(thread)