Check out our recent review on adenosine. A lot of new discoveries suggesting its tremendous potential in translation, among others, Parkinson's disease and insomnia. www.jneurosci.org/content/45/4...

Adenosine in the Brain: Recent Progress on Detection, Function, and Translation

Although adenosine was identified in the brain many decades ago, our understanding of when, where, and how it functions has expanded rapidly in recent years, driven in part by innovative technological...

jneurosci.org

A tour de force study by my colleague Tianyi Mao's lab @volluminstitute.bsky.social. Must read if one is interested in interoception, the insular cortex, or circuit architecture of associative cortices. www.biorxiv.org/content/10.1...

Neuronal architecture of the mouse insular cortex underlying its diverse functions

The insular cortex integrates interoceptive and exteroceptive information to mediate bodily homeostasis, emotion, learning, and potentially consciousness.[1][1]–[4][2] However, the cellular and circui...

biorxiv.org

‪Glad to share that our CKAR3 sensor for in vivo PKC activity imaging is now out at @natcomms.nature.com. Congrats to the team, especially co-first authors Takaki Yahiro and @baylesslandon.bsky.social. www.nature.com/articles/s41...

For the first time, scientists using #cryoelectron microscopy have discovered the structure and shape of key receptors connecting #neurons in the brain’s cerebellum, which plays a critical role in functions such as coordinating movement, balance and cognition. #OHSUResearch bit.ly/4b9gOw9