Could food additives make gut bacteria more aggressive? New findings in mice reveal carboxymethylcellulose & polysorbate 80 selected for adherent-invasive Escherichia coli mutations linked to ⬆️ motility, invasion and pro-inflammatory activity

A metatranscriptomics pipeline identifies a neutrophil elastase inhibitor that preserves the colonic epithelial barrier  Learn more how these translational findings might benefit patients with IBD @sigtrans-sttt.bsky.social 

A microbiome meta-transcriptomics pipeline identifies a neutrophil elastase inhibitor that protects the colonic epithelial barrier - Signal Transduction and Targeted Therapy

Signal Transduction and Targeted Therapy - A microbiome meta-transcriptomics pipeline identifies a neutrophil elastase inhibitor that protects the colonic epithelial barrier

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Are you looking for one place to keep up to date on what's new and interesting in the gut microbiome from bedside to plate? Then you might enjoy our newsletters: https://gutmicrobiotaforhealth.com/latest-issues/

Can food-specific microbiome data guide personalized nutrition? New findings show species-level links between specific foods and gut microbes — highlighting the potential to move beyond generic dietary advice. 👉 https://shorturl.at/E6qvZ

New findings establish a scalable computational framework for high-throughput discovery of gut microbial β-glucuronidase inhibitors, facilitating the translational potential to reduce drug gastrointestinal toxicity Read more: https://tinyurl.com/3berxevw

What is new on the role of #FMT in the clinical and regulatory landscape in Europe? Céline Druart delves into why the SoHO Regulation for innovation and patient access: https://www.gutmicrobiotaforhealth.com/from-regulation-to-opportunity-shaping-the-future-of-microbiome-based-therapies-in-europe/

Are you looking for one place to keep up to date on what's new and interesting in the gut microbiome from bedside to plate? 👉 Then you might enjoy our newsletters: https://gutmicrobiotaforhealth.com/latest-issues/

The gut microbiome is one of the six domains that integrates the new @isappscience.bsky.social-led definition of gut health While no single test can establish gut health, patient-reported outcomes are a key part of any valid gut health assessment   👇👇👇

Is it time to speak of a gut-bone axis? This review underscores the potential of dietary interventions targeting gut microbiota modulation as a novel therapeutic approach to improve skeletal health in high-risk populations: https://tinyurl.com/246eye2p

What do we mean by gut health? A new Consensus Statement puts forward a definition of ‘gut health’ to bring some clarity to a term that is widely used but often ill-defined:

A global consensus establishes a basis for measuring and improving gut health

While “gut health” is becoming a popular term, mainly in media and marketing claims but also in the clinical context, researchers have not yet nailed down a definition. Now, a global group of 13 scientists and clinicians updates a consensus definition of gut health and implications from bench to bedside.

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🇪🇺 Where are we on microbiome-based therapies? Céline Druart explains why the SoHO Regulation is both a challenge and an opportunity for innovation and patient access: https://www.gutmicrobiotaforhealth.com/from-regulation-to-opportunity-shaping-the-future-of-microbiome-based-therapies-in-europe/

Frequent digestive symptoms affect 1 in 4 adults worldwide—even without a GI diagnosis. Recent research shows that diet and the gut microbiome are key factors for targeted interventions and symptom relief. Learn more https://shorturl.at/v15Ut

Dietary advice in #IBD isn't one-size-fits-all Richard Hansen & Chen Sarbagili discuss why fiber, diet quality, and the #gutmicrobiome need to be considered in IBD: https://www.gutmicrobiotaforhealth.com/rethinking-diet-and-the-gut-microbiome-in-ibd-from-risk-to-treatment-and-beyond/

Human gut microbiome composition shows life stage-specific trends, but develops along distinct trajectories influenced by multiple factors across the life course This review updates implications for human physiology via @febsletters.bsky.social  https://tinyurl.com/2w5fxpfk

A major regulatory shift in Europe is reshaping microbiome-based therapies. Céline Druart explains why the SoHO Regulation (Substances of Human Origin) is both a challenge and an opportunity for innovation and patient access. Read the full interview: https://shorturl.at/bEXJY

Could microbial signatures predict postoperative recurrence of Crohn's disease? Sun-Ho Lee et al. update mechanisms across the preclinical phase of CD and postoperative recurrence Gut - @bmj.com  https://tinyurl.com/57j7ezjy

Recent studies have challenged the previous belief that obesity was solely a result of excessive caloric intake This review explores the knowns and unknowns of the role of gut microbiota in childhood obesity: https://tinyurl.com/4u4u6pzk

Can probiotic drinks boost our brain health? New findings suggest that probiotic yogurt might influence how the brain and gut interact, but more research is needed to understand their importance @bmj.com 

Effects of a probiotic fermented dairy product on hippocampal metabolites, structure and function: an 8-week randomised, placebo-controlled trial in healthy women

Background Fermented foods are a promising yet underexplored intervention for influencing brain function and mental health through the gut–brain axis. Objective The objective of this study was to evaluate the impact of a dairy product fermented with probiotic bacteria on aspects of brain structure...

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Gut microbiome-related interventions matter for the management of disorders of gut-brain interaction  Juan Manuel Mendive, PhD, MD, explains how the gut microbiome improves outcomes of primary care patients with IBS 👇👇👇

The balance between dietary protein and fiber is more important than fiber alone Rob V Bryant, Alice Day et al. update how dietary protein shapes GI tract and colonic microbiome @natrevgastrohep.nature.com  https://tinyurl.com/36shzbe7

In #IBD, dietary advice is rarely one-size-fits-all. Richard Hansen and Chen Sarbagili discuss why fiber, diet quality, & the #gutmicrobiome need to be considered across different disease stages, from risk to treatment & maintenance Watch the interview https://shorturl.at/CpHFA

The advice of following a high-fiber diet for constipation is outdated  The first-ever guidelines available provide a clinician-friendly tool to help you with the right dietary advice: https://tinyurl.com/5v7u4ve2

Nutrition can help in the prevention and management of IBD This timely review in @natrevgastrohep.nature.com covers where we are and the major steps on integrating precision nutrition for better IBD care: https://tinyurl.com/54ump3kj

What’s next for microbiome-targeted therapies and personalized nutrition from bench to bedside?  The report of the leading international conference #GMFH2026 is live 👉 https://tinyurl.com/6au6n77b

Can probiotic drinks boost our brain health? New findings suggest that probiotic yogurt might influence how the brain and gut interact, but more research is needed to understand its importance @bmj.com 

Effects of a probiotic fermented dairy product on hippocampal metabolites, structure and function: an 8-week randomised, placebo-controlled trial in healthy women

Background Fermented foods are a promising yet underexplored intervention for influencing brain function and mental health through the gut–brain axis. Objective The objective of this study was to evaluate the impact of a dairy product fermented with probiotic bacteria on aspects of brain structure...

tinyurl.com

Gut microbiome-related interventions matter for the management of disorders of gut-brain interaction  Juan Manuel Mendive, PhD, MD, explains how the gut microbiome improves outcomes of primary care patients with IBS 👇👇👇

What’s next for microbiome-targeted interventions in clinical practice? The #GMFH2026 brought together experts from 27 countries to discuss personalized nutrition, dietary fiber, microbiome-based therapies, IBS, IBD, metabolic diseases, and cancer. Read the report 👇 https://tinyurl.com/mtjf54zs

Dietary interventions matter for chronic constipation The first-ever guidelines available provide a clinician-friendly tool to help you with the right dietary advice: https://www.gutmicrobiotaforhealth.com/specific-probiotic-species-and-strains-could-help-manage-chronic-constipation-in-adults/

New findings from Elena Verdu, Alberto Caminero & colleagues found microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis  Peanut-degrading Rothia abundance was also linked to higher peanut threshold in patients: https://tinyurl.com/4fpcnbuw

New findings from seven microbiome testing companies highlight the systemic issue of poor comparability that plagues the industry, due to methodological variability Also the stool reference material does not represent an absolute “ground truth”:

Evaluating the analytical performance of direct-to-consumer gut microbiome testing services - Communications Biology

Comparative analysis of DTC gut microbiome testing services reveals significant methodological variability, underscoring the need for standardized reference materials and guidelines to ensure reproducibility and reliability in commercial microbiome testing.

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