Come and work with us! We have a PostDoc position at the intersection of ML and Biogeoscience within the TERRA excellence cluster @terra-cluster.org, w/ Senckenberg. Be part of a great ML and Geo community and use ML to investigate fire and its impact on global vegetation🔥 🌱🌳 www.mackelab.org/jobs/

This is a great opportunity to work at the intersection of ML and Biogeoscience! Based within the outstanding research community of Tübingen. Reach out if you are interested!

Machine Learning in Science@mackelab.bsky.social · 4mo ago

Come and work with us! We have a PostDoc position at the intersection of ML and Biogeoscience within the TERRA excellence cluster @terra-cluster.org, w/ Senckenberg. Be part of a great ML and Geo community and use ML to investigate fire and its impact on global vegetation🔥 🌱🌳 www.mackelab.org/jobs/

@mackelab.bsky.social is at @cosynemeeting.bsky.social #cosyne2026 in Lisbon with two posters presented by PhD students from the lab. Thread below on the projects 👇

On my way from Munich to Grenoble 🚞 to co-lead a 3-day SBI tutorial + hackathon together with @danielged.bsky.social, organised by Pedro Rodriguez and @ugrenoblealpes.bsky.social. Excited to meet researchers from across France, many bringing their own simulators 🚀

1/ 🌀 New paper alert! We introduce Dingo-T1, a flexible transformer-based deep learning model for gravitational-wave (GW) data analysis. It adapts to different detector & frequency settings, improving inference efficiency and flexibility 🚀 #AI #MachineLearning #Physics #Astronomy #AcademicSky

Finally got the job ad—looking for 2 PhD students to start spring next year: www.gao-unit.com/join-us/ If comp neuro, ML, and AI4Neuro is your thing, or you just nerd out over brain recordings, apply! I'm at neurips. DM me here / on the conference app or email if you want to meet 🏖️🌮

I’m at NeurIPS in San Diego this week to present cool work on foundation models for SBI! Most importantly, I’ll be around to meet people and discuss science. 👨‍🔬

Machine Learning in Science@mackelab.bsky.social · 8mo ago

Second, come by to check out NPE-PFN: We leverage the power of tabular foundation models for training-free and simulation-efficient SBI. SBI has never been so effortless! By @vetterj.bsky.social, Manuel Gloeckler, @danielged.bsky.social, @jakhmack.bsky.social 4/11

Our group is at NeurIPS and EurIPS this year with four papers and one workshop poster. If you are either curious about SBI with autoML, with foundation models, or on function spaces or about differentiable simulators with Jaxley, have a look below 👇 1/11

I’m super excited to present our new work in #Eurips2025 and #Neurips2025! We developed FNOPE: a new simulation-based inference (SBI) method which excels at inferring function-valued parameters! Paper: openreview.net/forum?id=yB5... Code: github.com/mackelab/fnope (1/9)

MackeLab has grown! 🎉 Warm welcome to 5(!) brilliant and fun new PhD students / research scientists who joined our lab in the past year — we can’t wait to do great science and already have good times together! 🤖🧠 Meet them in the thread 👇 1/7

Simulation-based inference (SBI) has transformed parameter inference across a wide range of domains. To help practitioners get started and make the most of these methods, we joined forces with researchers from many institutions and wrote a practical guide to SBI. 📄 Paper: arxiv.org/abs/2508.12939

Simulation-Based Inference: A Practical Guide

A central challenge in many areas of science and engineering is to identify model parameters that are consistent with prior knowledge and empirical data. Bayesian inference offers a principled framewo...

arxiv.org

🎉 sbi participated in GSoC 2025 through @numfocus.bsky.social and it was a great success: our two students contributed major new features and substantial internal improvements: 🧵 👇

Congrats to Dr Michael Deistler @deismic.bsky.social, who defended his PhD! Michael worked on "Machine Learning for Inference in Biophysical Neuroscience Simulations", focusing on simulation-based inference and differentiable simulation. We wish him all the best for the next chapter! 👏🎓

The Macke lab is well-represented at the @bernsteinneuro.bsky.social conference in Frankfurt this year! We have lots of exciting new work to present with 7 posters (details👇) 1/9

I've been waiting some years to make this joke and now it’s real: I conned somebody into giving me a faculty job! I’m starting as a W1 Tenure-Track Professor at Goethe University Frankfurt in a week (lol), in the Faculty of CS and Math and I'm recruiting PhD students 🤗

a man wearing a white shirt and tie smiles in front of a window

ALT: a man wearing a white shirt and tie smiles in front of a window

media.tenor.com

From hackathon to release: sbi v0.25 is here! 🎉 What happens when dozens of SBI researchers and practitioners collaborate for a week? New inference methods, new documentation, lots of new embedding networks, a bridge to pyro and a bridge between flow matching and score-based methods 🤯 1/7 🧵

Looky Looky! 😍🥳👏 arxiv.org/abs/2508.12939 Super fun project, I ❤️ed coauthoring w/ @sbi-devs.bsky.social. Great lead by @deismic.bsky.social & @janboelts.bsky.social. Contribs by many talented people @jakhmack.bsky.social. 🙏 to #BenjaminKurtMiller for the kickstart! @helmholtzai.bsky.social

Simulation-Based Inference: A Practical Guide

A central challenge in many areas of science and engineering is to identify model parameters that are consistent with prior knowledge and empirical data. Bayesian inference offers a principled framewo...

arxiv.org

New preprint: SBI with foundation models! Tired of training or tuning your inference network, or waiting for your simulations to finish? Our method NPE-PF can help: It provides training-free simulation-based inference, achieving competitive performance with orders of magnitude fewer simulations! ⚡️

I have been genuinely amazed how well tabpfn works as a density estimator, and how helpful this is for SBI ... Great work by @vetterj.bsky.social, Manuel and @danielged.bsky.social!!

Machine Learning in Science@mackelab.bsky.social · last yr.

New preprint: SBI with foundation models! Tired of training or tuning your inference network, or waiting for your simulations to finish? Our method NPE-PF can help: It provides training-free simulation-based inference, achieving competitive performance with orders of magnitude fewer simulations! ⚡️

My first paper on simulation-based inference (SBI) as part of @mackelab.bsky.social! Exciting work on adapting state-of-the-art foundation models for posterior estimation. Almost plug-and-play, and surprisingly effective. Paper/code in thread below 🧵

Machine Learning in Science@mackelab.bsky.social · last yr.

New preprint: SBI with foundation models! Tired of training or tuning your inference network, or waiting for your simulations to finish? Our method NPE-PF can help: It provides training-free simulation-based inference, achieving competitive performance with orders of magnitude fewer simulations! ⚡️

New paper in Geophysical Research Letters led by Vjeran Višnjević mapping out ice shelf areas which are maintained by local precipitation only doi.org/10.1029/2024...

Mapping the Composition of Antarctic Ice Shelves as a Metric for Their Susceptibility to Future Climate Change

We categorize Antarctic ice shelves into two parts: local meteoric ice and continental meteoric ice Buttressed ice shelves composed primarily of local meteoric ice are identified as being particu...

doi.org

Have I been to Antarctica? No. But my colleagues have, and we can learn a lot from the data they collected! Really happy to share that our work is now published!

Machine Learning in Science@mackelab.bsky.social · last yr.

Thrilled to share that our paper on using simulation-based inference for inferring ice accumulation and melting rates for Antarctic ice shelves is now published in Journal of Glaciology! www.cambridge.org/core/journal...

More great news from the SBI community! 🎉 Two projects have been accepted for Google Summer of Code under the NumFOCUS umbrella, bringing new methods and general improvements to sbi. Big thanks to @numfocus.bsky.social, GSoC and our future contributors!

Great news! Our March SBI hackathon in Tübingen was a huge success, with 40+ participants (30 onsite!). Expect significant updates soon: awesome new features & a revamped documentation you'll love! Huge thanks to our amazing SBI community! Release details coming soon. 🥁 🎉

🎓Hiring now! 🧠 Join us at the exciting intersection of ML and Neuroscience! #AI4science We’re looking for PhDs, Postdocs and Scientific Programmers that want to use deep learning to build, optimize and study mechanistic models of neural computations. Full details: www.mackelab.org/jobs/ 1/5

Excited to present our work on compositional SBI for time series at #ICLR2025 tomorrow! If you're interested in simulation-based inference for time series, come chat with Manuel Gloeckler or Shoji Toyota at Poster #420, Saturday 10:00–12:00 in Hall 3. 📰: arxiv.org/abs/2411.02728

Compositional simulation-based inference for time series

Amortized simulation-based inference (SBI) methods train neural networks on simulated data to perform Bayesian inference. While this strategy avoids the need for tractable likelihoods, it often requir...

arxiv.org

🥳Great news, our JOSS paper "sbi reloaded" has been accepted! 🎉 This community lead by the fine folks of @sbi-devs.bsky.social is very welcoming and super fun to work with! I learn with every discussion I have. paper: joss.theoj.org/papers/10.21... review: github.com/openjournals...

[REVIEW]: sbi reloaded: a toolkit for simulation-based inference workflows · Issue #7754 · openjournals/joss-reviews

Submitting author: @janfb (Jan Boelts) Repository: https://github.com/sbi-dev/sbi Branch with paper.md (empty if default branch): joss-submission-2024 Version: v0.24.0 Editor: @boisgera Reviewers: ...

github.com

It's been a blast, thanks to @sbi-devs.bsky.social ! This week's hackathon was phenomenal! 🙏 😍 The sbi hackathon welcomed about 25 people in Tübingen with contributions spanning the globe , e.g. 🇺🇸🇯🇵🇧🇪🇩🇪. Wanna see, what we did? Check out the PRs👇 github.com/sbi-dev/sbi/...

Pull requests · sbi-dev/sbi

sbi is a Python package for simulation-based inference, designed to meet the needs of both researchers and practitioners. Whether you need fine-grained control or an easy-to-use interface, sbi has ...

github.com

🙏 Please help us improve the SBI toolbox! 🙏 In preparation for the upcoming SBI Hackathon, we’re running a user study to learn what you like, what we can improve, and how we can grow. 👉 Please share your thoughts here: forms.gle/foHK7myV2oaK... Your input will make a big difference—thank you! 🙌

🚀 Join the 4th SBI Hackathon! 🚀 The last SBI hackathon was a fantastic milestone in forming a collaborative open-source community around SBI. Be part of it this year as we build on that momentum! 📅 March 17–21, 2025 📍 Tübingen, Germany or remote 👉 Details: github.com/sbi-dev/sbi/... More Info:🧵👇