I would like to thank Maarten Naesens, MD for the opportunity to write my position statement on where the field of transplantation needs to shift to. Now is the time to improve quality and participation of life after transplant. bit.ly/4jQToAP #openaccess

Frontiers Publishing Partnerships | Life After Kidney Transplantation: The Time for a New Narrative

The first successful kidney transplant in December 1954 between the Herrick brothers ushered in a new field of medicine. Over the almost seventy years, tho...

bit.ly

Thanks for allowing me to part of the conversation. My final thoughts: This research underscores that AMR is a continuum and the leading cause of graft failure. There is a critical need to understand AMR + develop preventive strategies and treatments so that grafts are not lost. #nephjc

#nephjc COI Biogen Worked in kidney transplant since 2017. Consulted for CSL Behring on AMR + now with Biogen KTX since August 2004

Need to depart. Take care everyone. If you ever have questions regarding #adpkd, contact me any time. #nephjc

The pain was a real issue before kidney transplant + has continued post kidney transplant. It is difficult to predict its occurrence #nephjc

Nephrology Journal Club@nephjc.bsky.social · last yr.

😖 Pain is common in ADPKD—ruptured cysts, infections, or just pressure effects. But severity ≠ size. Tiny cysts can cause big trouble. #NephJC

There can be difference in families. I had PKD1 + my sister has PKD2. I went into kidney failure at 43 + she is 60 with native kidneys #nephjc

Nephrology Journal Club@nephjc.bsky.social · last yr.

ADPKD = caused by mutations in PKD1 or PKD2 — and sometimes others. Genetics shape phenotype & prognosis. #NephJC

@gratefull080504.bsky.social No COI related to #ADPKD Several generations of our family have been impacted by #adpkd including me #nephjc

I will see you tonight #nephjc #adpkd

Nephrology Journal Club@nephjc.bsky.social · last yr.

⏰2 hours to chat It’s #NephJC time! Tonight we dive into something BIG —literally & figuratively: the first-ever @kdigo.org 2025 ADPKD guidelines 🧬 Finally, this disease gets its own spotlight. #NephJC

Like Tracy Morgan, I am a kidney transplant recipient and I had a poisoning a year ago. I almost died. Food poisoning is serious issue for kidney transplant recipients. I hope his kidney is doing well after experiencing vomiting.

Phil Lewis@phillewis.bsky.social · last yr.

Tracy Morgan says he's "doing ok now" and said his medical episode last night was food poisoning

A very nice overview of the progress in #xenotransplantation www.nytimes.com/2025/03/10/h...

For Patients Needing Transplants, Hope Arrives on Tiny Hooves (Gift Article)

Some scientists are confident that organs from genetically modified pigs will one day be routinely transplanted into humans. But substantial ethical questions remain.

nytimes.com

Please consider RT #nephsky

National Kidney Foundation@kidney.org · last yr.

We urge the Administration and Congress to reconsider and roll back these actions immediately so potential cuts can be made in a thoughtful and safer manner. To do otherwise may result in absolute tragedy for the American people.

Explore this gift article from The New York Times. You can read it for free without a subscription. www.nytimes.com/2025/02/03/h... Good background on the forthcoming #xenotransplanation trial

F.D.A. Approves Studies of Pig Organ Transplants for Kidney Patients (Gift Article)

The research offers hope to tens of thousands of patients with kidney failure who are on a long waiting list for an organ transplant.

nytimes.com

The FDA has provided United Therapeutics approvaal to begin #xenotransplantation trials in human mid-year 2025

StockTitan@stocktitan.net · 2y ago

#UTHR United Therapeutics Corporation Announces FDA Clearance of its Investigational New Drug Application for the UKidney Xenotransplantation Clinical Trial https://www.stocktitan.net/news/UTHR/united-therapeutics-corporation-announces-fda-clearance-of-its-i9jdr5owbet7.html

@kidneytransplant.bsky.social : It is always great to see you! I am thrilled to be involved with the TRANSCEND trial. AMR is huge unmet need in kidney transplantation.

Yasir Qazi@kidneytransplant.bsky.social · 2y ago

Always a pleasure to hear Kevin Fowler @gratefull080504.bsky.social to give such an amazing patient perspective. Here at the TRANSCEND investigator meeting. If you have been diagnosed with Antibody mediated rejection please discuss with your provider the clinical trials available in this space

@kidneytransplant.bsky.social : The MediBeacon device will have a role in kidney transplantation.

Yasir Qazi@kidneytransplant.bsky.social · 2y ago

About time we had something fancy to assess the renal function ! Nephrology has all the Rizz right now ! #ThanksFDA www.medicaldevice-network.com/news/fda-med...

@askrenal.bsky.social what is the lowest FDA approved use of Ozempic in DKD patients?

@sumitmohan.bsky.social : As you and your colleagues point in your article, patients are not included in this discussion. Will the OOPTN Modernization address this gap in shared decision making? #nephjc

Sumit Mohan@sumitmohan.bsky.social · 2y ago

In 2022, we did fewer than 20,000 kidney transplants and discarded thousands more…. and it took nearly 30 million offers. Kidneys that reached patients were turned down twice as often compared to 2 years prior. #broken #kidney #allocation

Great work by @sumitmohan.bsky.social + Jesse Schold,PhD "Moreover, it is not clear to what extent organ discard is a function of inefficiencies that are overwhelming the system, rather than a consequence of organ quality itself." Hopefully the OPTN Modernization Initiative elevates #patientvoice

Swapnil Hiremath 🍁🇨🇦@hswapnil.medsky.social · 2y ago

Hugely shocking (to me) high discard rates which have risen post changes to improve the state of things (KAS250) www.kireports.org/article/S246... From @sumitmohan.bsky.social et al in @kireports.bsky.social The discussion is very illuminating for those like me who can’t fathom this #NephSky

The issue is not pain management. It is the fact dialysis treatment that has not evolved into a treatment that allows someone to participate in life. That is where the discussion needs to be focused upon. #nephjc

Nephrology Journal Club@nephjc.bsky.social · 2y ago

Life is a Battle… and so is pain management in CKD. 💊 Check out these heat maps by @kidneyboy.bsky.social on 2018 —NSAIDs use? 💊 Opioid? 🔥 Are we over-relying on pain control in CKD? #NephJC

#nephjc I need to depart soon. The need for innovation in dialysis treatments is deeply needed. Nephrologists need better treatments so they can offer their patients more. This is where I would like to shift the conversation. Also @hswapnil.medsky.social and I agree on many subjects!

Kudos again to the sponsor! PROMs are needed in #kidneydisease #nephjc

Nephrology Journal Club@nephjc.bsky.social · 2y ago

Secondary Outcomes Additional reports (outside of the BPI questions) of pain indicators and opioid use, as well as pain-related clinical events. The study also examined symptoms that accompany pain (i.e. anxiety, depression), and symptoms possibly related to pain treatments. #NephJC

Agree @hswapnil.medsky.social Well done. #nephjc

Swapnil Hiremath 🍁🇨🇦@hswapnil.medsky.social · 2y ago

Impressively - patient partners were involved in all aspects of the trial! See figure Kudos to UPenn trial group and the NIDDK to make this happen #NephJC

#nephjc If a treatment results in 1/2 the population experiencing pain , shouldn't the priority be on finding improved dialysis treatments?

#nephjc The fact that 50% of hemodialysis patients experience pain underscores the need for innovation in dialysis treatments.

#nephjc @gratefull080504.bsky.social No COI

I will be at #nephjc tonight.

Nephrology Journal Club@nephjc.bsky.social · 2y ago

Tonite 1/21/25 exclusively on BlueSky at 9pm EST, #NephJC will discuss the use of cognitive behavioral therapy in dialysis patients for decreasing the sensation of pain and pain associated symptoms. #MedSky #NephSky www.nephjc.com/news/hope-hd-trial

The approval of the MediBeacon Inc.of the TGfR is a big first step in the advancement of 3kidneyhealth. eGFR is an insensitive biomarker that many times does not provide an accurate assessment of kidney function. This will have broad implications in patient care.

༺DailyHemo༻@dailyhemo.bsky.social · 2y ago

MediBeacon® Transdermal GFR System Receives FDA Approval to Assess Kidney Function. www.medibeacon.com #RenalSky #MedSky #HealthSky

This is a huge step forward in advancing #kidneyhealth For full disclosure I am consultant for MediBeacon.

༺DailyHemo༻@dailyhemo.bsky.social · 2y ago

MediBeacon® Transdermal GFR System Receives FDA Approval to Assess Kidney Function. www.medibeacon.com #RenalSky #MedSky #HealthSky

I enjoyed my first #nephjc on @bsky.app last night. Looking forward to building out my #nephjc #kidneydisease community

#nephjc Have to leave a little early tonight. Take care everyone