Conformational dynamics, RNA binding, and phase separation regulate the multifunctionality of rabies virus P protein - Nature Communications

Viral proteins can achieve high multifunctionality, but mechanisms are poorly understood. This study shows structural flexibility of rabies virus P protein enables RNA binding and phase separation to ...

nature.com

Structural analysis reveals how tetrameric tyrosine-phosphorylated STAT1 is targeted by the rabies virus P-protein

The cryo-EM structure of a DNA-bound STAT1 tetramer shows how it can be antagonized by a viral protein.

science.org

Analysis of mechanisms of the rabies virus P protein-nucleocapsid interaction using engineered N-protein peptides and potential applications in antivirals design

The Phosphoprotein (P protein) of the rabies virus has multiple roles in virus replication. A critical function is to act as a cofactor in genome repl…

sciencedirect.com