🎬 More about TIGR-Tas, featuring THE first TIGR-Tas movie by @maxewilkinson.bsky.social Absolutely thrilled to work alongside Max Wilkinson, Makoto Saito, and an incredible team, under the fantastic leadership of Feng Zhang! 🔬✨ 🚀 Exciting times ahead! More soon :)

Max Wilkinson@maxewilkinson.bsky.social · 2y ago

we recently found some really neat RNA-guided DNA-cutting systems in phages. Despite remarkable similarities to CRISPR systems, including encoding guide RNAs in arrays, they appear entirely evolutionarily distinct (but definitely related to snoRNAs 🤓) We decided to call them TIGR-Tas systems 🐯

🚀 Thrilled to share our latest work from Zhang Lab, now published in Science (www.science.org/doi/10.1126/...) We introduce TIGR-Tas, a PAM-free, compact, modular RNA-guided DNA-targeting system in prokaryotes & their viruses. More details coming soon 👀 #TIGR #RNA #GeneEditing #CRISPR