This epic paper, which has been a heroic 10 year journey for the lead author, Ricardo Barrientos, is finally out in Cell today! Many thanks to all co-authors, especially Billie Meadowcroft and Andela Saric for their beautiful MD simulations www.cell.com/cell/fulltex...

Basement membrane turnover controls cell shape

Basement membranes are scaffolds of proteins, like collagen, that give organs shape. During development, basement membranes must adapt to the growing organ. We infer how fast the basement membrane ada...

cell.com

Naked mole-rat queens produce a chemical that prevents other females in their colony from reproducing go.nature.com/4bJ3ykK

How naked mole-rat queens stop rivals reproducing

The scent of a single chemical, made only by the queen, alters hormone production in other females.

go.nature.com

🚨 We are searching for 2 PhD students to join our CRC 1550 'Molecular circuits of heart disease' project - a joint venture with @eldadtzahor.bsky.social to investigate the mechanisms underlying intercellular communication and how these promote cardiac repair and regeneration. Please share 🙏🐟🐭🧬🔬

I’m at #SMBE2026 this week. My lab is looking to hire a postdoc to study the genetic and developmental mechanisms underlying the evolution of organs and cell types. Please reach out if you’re interested!

We are recruiting! We invite applications from highly motivated PhD candidates interested in developmental biology, imaging, and in situ structural biology to study the biogenesis and plasticity of motile cilia in development and disease.

He Lab - Our Research

muhelab.com

😲 Homing pigeon navigation relies on superparamagnetic macrophages under overcast conditions | Science “Pigeon liver tissue exhibits superparamagnetic properties and contains iron-positive MHC II+ macrophages.” www.science.org/doi/10.1126/...

“New NIH policy demands advance approval of any foreign co-authors” wp.me/p3ct3-3Kd Can anyone confirm the source?

New NIH policy demands advance approval of any foreign co-authors

New reporting in Science from Jeffrey Brainard and Jocelyn Kaiser informs us of new policy that is apparently being communicated by POs in relationship to progress reports. The takeaway message is …

wp.me

Excited to share our latest paper! We found that large pieces of the human genome can transfer between cells upon direct contact, endowing recipient cells with heritable phenotypic changes. @cp-cell.bsky.social (1/7) www.cell.com/cell/fulltex...

@science.org is looking for a new editor to look after regenerative medicine and neuroscience submissions. Come join us! Check out this Associate or Senior Editor opportunity recruiting.ultipro.com/AME1123ASEM/...

recruiting.ultipro.com

For 40 years the 8-nt ‘Kozak Sequence’ was thought to mark sites of translation initiation. In a new study, we revise this model by identifying an ~80-nt sequence—the extended Translation Initiation Sequence (eTIS)— that guides ribosomes to correct start sites. 🧵 www.biorxiv.org/content/10.6...

We now have genome browsers on our UCSC mirror at genome.senckenberg.de for the 1033 mammal and 866 bird assemblies, showing spliceAi, reference-based and ref-integrated TOGA2 tracks. Tables with links to all browsers are genome.senckenberg.de/TOGA2Mammali... & genome.senckenberg.de/TOGA2Aves.html

How armadillos gather foliage for their nests

We’re looking for a technician to join our lab in Dresden - help manage the lab and work with us on a cool 'stem cell zoo' comparison projects! 🐁🚶‍♀️🦏🐒 Apply by May 21! tud.link/wbqrwm

Physics of Life Dresden@poldresden.bsky.social · 3mo ago

🚨 #JobAlert: Lab Technician. Please share with your colleagues! 👩‍🔬The Ebisuya lab @ebisuyamiki.bsky.social is looking for an experienced technician in molecular & cell biology to join their interdisciplinary team. Apply now! Learn more here 👉 tud.link/wbqrwm 🗓️Application deadline: May 21.

We are recruiting one postdoc fellow and one Junior Specialist (for those finishing college and planning to pursue a PhD) in regenerative biology and extreme physiology. scvrb-core.ucsf.edu/~huang/lab/R... Please spread the news. Interested candidates can email me directly.

Wow, almost 4-week torpor induced in mice! And possible treatment for cancer! www.biorxiv.org/content/10.6...

Do you want to try scratching garlic on the skin to repel mosquitoes? A phytoscreen identifies a garlic compound as a deterrent of mating and egg laying in Drosophila and mosquitoes www.cell.com/cell/abstrac...

A phytoscreen identifies a garlic compound as a deterrent of mating and egg laying in Drosophila and mosquitoes

This study provides a paradigm for how the vast chemical diversity inherent in agricultural crops can be screened to identify compounds that deter insect disease vectors and pests. Such a “phytoscreen...

cell.com

🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders? In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸 🔗 www.science.org/doi/10.1126/... #EvoDevo

www.sciencenews.org/article/rege... @josanesousa.bsky.social @gabrielalima19.bsky.social @perezlouise.bsky.social @patyschneider22.bsky.social

Regeneration of fins and limbs relies on a shared cellular playbook

The findings strengthen the case that regeneration is an old trait, offering insights into how complex tissues rebuild themselves.

sciencenews.org

Happening today at 12pm EST - join us for an exciting Zone 3 (Americas) webinar focused on Hydroid regeneration! More information and zoom links can be found at: isrbio.org/webinars

We know many fish and amphibians can regenerate the heart. How about reptiles? A landmark paper from @vickaryouslab.bsky.social to fill this gap. Glad to be a part of this study. @isrbio.bsky.social @evodevopanam.bsky.social @socdevbio.bsky.social www.nature.com/articles/s41...

Male octopuses use a specialized arm that acts as both a sensory and reproductive organ to navigate the female’s mantle, locate oviducts, and transfer sperm. These findings reveal how sensory systems shape reproductive behavior and drive speciation. Learn more in Science: https://scim.ag/4dYMtFq

The EMBO Global Investigator Network supports group leaders setting up their laboratories in #Chile, #India, #Japan, #Singapore and #Taiwan. Apply now with a deadline of 1 May 14:00 CEST. 🧪 https://www.embo.org/funding/fellowships-grants-and-career-support/global-investigator-network/ #LifeSciences

This is an excellent summary of our work. www.growkudos.com/publications...

A new role of a gene in brain development, cancer, and evolution

Many “master” genes control how the brain develops and how cancers form, but they often act only weakly on their own. At the same time, hundreds of genes that are active in specific tissues have uncle...

growkudos.com

Our new paper led by @XiaoxinChen2024 is out in @pnas.org! bit.ly/4785aCD We built a tissue atlas of ~2K transcription regulators ➔ identified Tox3 as a long-sought Atoh1 amplifer in cerebellar development, tumorigenesis & evolution. 1/10 📢 We're recruiting postdocs in Evo-Devo!

It’s out! 🐟 We compared three regeneration superstars—axolotl, zebrafish, and Polypterus—to ask how animals regrow limbs and fins. We find shared core processes, and other programs fine-tuned by evolution in surprising, lineage-specific ways. tinyurl.com/mpftkn7y

A landmark discovery in cancer neuroscience! Why is the incidence of Alzheimer’s disease (AD) lower in patients with a history of cancer? CELL: Peripheral cancer attenuates amyloid pathology in Alzheimer’s disease via cystatin-c activation of TREM2 www.cell.com/cell/fulltex...

Peripheral cancer attenuates amyloid pathology in Alzheimer’s disease via cystatin-c activation of TREM2

Peripheral cancer inhibits amyloid pathology and rescues cognition of Alzheimer’s disease through secretion of cystatin-c (Cyst-C), which binds amyloid oligomers and activates TREM2 in microglia and e...

cell.com

So proud of this incredible team and all we accomplished this year! We’re looking for 1-2 postdocs to explore evo-devo, organ regeneration, extreme physiology, non-traditional animals, and SUPERMAN 🦸‍♂️! Please spread out news. @isrbio.bsky.social @ahascience.bsky.social @socdevbio.bsky.social

Here is a copy of last year's Twitter thread explaining our preprint - jump to (21) for the new stuff 👀 Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function now revised and journal accepted at www.science.org/doi/10.1126/... 🧵👇

We've just been awarded a grant to study the cellular basis of regeneration – to track the progenitors of sensory organs in the context of leg regeneration, in our favourite crustacean tinyurl.com/parhyale, based on live imaging and cell tracking. The project involves some cool collaborations... 1/3

All new NIH funding opportunities should incorporate New Approach Methodologies, a suite of modern alternatives including computer modeling, AI and ‘organs-on-a-chip’ technologies. “NIH will no longer seek proposals exclusively for animal models.” www.drugdiscoverytrends.com/nih-announce...

NIH announces end to funding for animal-only studies - Drug Discovery and Development

Drug Discovery and Development covers strategies and technologies related to pharmaceutical research and development and drug formulation.

drugdiscoverytrends.com