One week left to apply for PhD and Postdoc positions at the @uni-wuerzburg.de site of our @nucleate-cluster.bsky.social Cluster of Excellence! Join our group or the lab of one of our outstanding colleagues to help shape the future of nucleic acid science. Apply here: nucleate-cluster.de/careers/

The NUCLEATE Cluster of Excellence is hiring! Shape the future of nucleic acid sciences 🧬 🚀 Group Leaders: All 3 locations (LMU, TUM, JMU Würzburg) 🔬 PhDs & Postdocs: Open call in Würzburg and speculative applications welcome! Deadline: Aug 16, 2026 👉 More info: nucleate-cluster.de/careers/

Our new preprint in collaboration with @meisterpeterf.bsky.social uncovers the molecular basis for condensin recruitment to X chromosomes in C. elegans and reveals atomic-level details of a previously unknown auto-inhibited state of condensin. www.biorxiv.org/cgi/content/short/2026.03.13.711519v1

Congratuations to our PhD Student @gurumoorthya.bsky.social on winning the Poster Award for his work on gene regulation by DNA loop extrusion and phase separation at the CNIO-CaixaResearch Frontiers Meeting on "Machines acting on DNA and RNA, a molecular mechanistic perspective"!

In our latest mini review, Toni Valdes and I discuss the potential role(s) of DNA superhelicity in the organization of chromosomes by SMC protein complexes, covering classical biochemistry experiments to recent single-molecule biophysics studies. doi.org/10.1042/BST2...

Adding a twist to the loops: the role of DNA superhelicity in the organization of chromosomes by SMC protein complexes

Structural maintenance of chromosomes (SMC) protein complexes, including cohesin, condensin, and the Smc5/6 complex, are integral to various processes in chromosome biology. Despite their distinct rol...

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