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Hafting-Fyhn Lab

@hafting.bsky.social

Systems neuroscience at University of Oslo

20 Posts308 Follower179 Folgt
Hafting-Fyhn Lab@hafting.bsky.social · 9mo ago

No GPS in the head? Path integration by entorhinal grid cells without the grid pattern. Interesting paper from Heidelberg. www.nature.com/articles/s41...

Grid cells accurately track movement during path integration-based navigation despite switching reference frames - Nature Neuroscience

Grid cells do not maintain a stable pattern during a self-motion-based task, but track animal movement in multiple local reference frames and reanchor to task-relevant objects, thus estimating local r...

nature.com

Carl T. Bergstrom@carlbergstrom.com · last yr.

Harvard today, your institution tomorrow. It's all part of the Project 2025 plan to destroy high education in America. All leading US universities depend on federal funding and tuition dollars from international students. They severely curtailed the former. Now they're eliminating the latter.

The Trump administration on Thursday halted Harvard University’s ability to enroll international students, taking aim at a crucial funding source for the nation’s oldest and wealthiest college in a major escalation in the administration’s efforts to pressure the elite school to fall in line with the president’s agenda.
The New York Times@nytimes.com · last yr.

Breaking News: The Trump administration halted Harvard’s ability to enroll international students, a major escalation in its battle with the school.

Hafting-Fyhn Lab@hafting.bsky.social · 2y ago

Knockout of aggrecan in PV+ interneurons eliminate the expression of PNNs labeled by WFA. KO animals showed similar long-term memory as controls, but showed lower level of anxiety-related behavior in an open field and zero maze. www.nature.com/articles/s41...

Differential impacts of germline and adult aggrecan knockout in PV+ neurons on perineuronal nets and PV+ neuronal function - Molecular Psychiatry

Molecular Psychiatry - Differential impacts of germline and adult aggrecan knockout in PV+ neurons on perineuronal nets and PV+ neuronal function

nature.com

Nori@catphrodite.bsky.social · 2y ago

Fascinating new study: The visual cortex in people (like me!! 👋) with #aphantasia processes visual info but doesn’t translate it into conscious images. This disconnect explains why they can “know” details (like layouts) without “seeing” them—mental pictures don’t fully form. (Can confirm!)

People who can’t picture images in their ‘mind’s eye’ still represent them in their brains

Imaging study of people with aphantasia reveals differences—but not a complete deficit—in visual processing area

science.org

Hafting-Fyhn Lab@hafting.bsky.social · 2y ago

In this preprint we see how activity in entorhinal cortex change during learning a non-spatial visual association task. Neurons in the MEC initially exhibited weak responses to visual cues but gradually developed strong tuning toward the rewarded trials. doi.org/10.1101/2024...

Task and Behavior-Related Variables Are Encoded by the Postrhinal and Medial Entorhinal Cortex During Non-Spatial Associative Learning

The medial entorhinal cortex (MEC) is pivotal in spatial computations and episodic memory. In particular, an animal’s position can be decoded from the activity of entorhinal grid cells. However, it re...

doi.org

Hafting-Fyhn Lab@hafting.bsky.social · 2y ago

Interesting study indicating that even a bit of air pollution (PM2.5) slow down marathon performance. Average Chicago Marathon times 8 minutes faster in a low-pollution year 2019 (~3 micrograms/cubic meter) than in a high-pollution year (~20 mi-g/m3). link.springer.com/article/10.1...

Running on Fumes: An Analysis of Fine Particulate Matter’s Impact on Finish Times in Nine Major US Marathons, 2003–2019 - Sports Medicine

Background Under controlled conditions and in some observational studies of runners, airborne fine particulate matter smaller than 2.5 microns in diameter (PM2.5) is associated with exercise performan...

link.springer.com

SpryOldLorax@spryoldlorax.bsky.social · 2y ago

I wish more people were literate enough to truly be able to read & understand this graph, and to be upset by it. Because it's upsetting! We pay SO MUCH MORE for healthcare, and have worse outcomes & lower life-expectancy. The data is clear: We are coming in last in the race for health & well-being.

A graph showing life expectancy (vertical axis) compared to health expenditures per capita (horizontal access) for more than a dozen countries. The USA stands alone way off to the right (expensive) and not nearly as high as any of the others (lower life expectancy).
Hafting-Fyhn Lab@hafting.bsky.social · 2y ago

BioRxiv: Knockout of ACAN in PV+ cells inhibit formation of WFA positiv perineuronal nets (PNNs) around PV+ cells. ACAN KO mice show lower level of anxiety-related behavior. In the morris watermaze they employ bolder search strategy, but long-term memory is the same. doi.org/10.1101/2024...

Deciphering the Role of Aggrecan in Parvalbumin Interneurons: Unexpected Outcomes from a Conditional ACAN Knockout That Eliminates WFA+ Perineuronal Nets

The transition from juvenile to adult is accompanied by the maturation of inhibitory parvalbumin-positive (PV+) neurons and reduced plasticity. This transition involves the formation of perineuronal n...

doi.org

Hafting-Fyhn Lab@hafting.bsky.social · 2y ago

Finally, recording from freely swimming larval zebrafish reveals place code. I wonder how it is in salmon returning to their natal creek. www.nature.com/articles/s41...

A population code for spatial representation in the zebrafish telencephalon - Nature

Using a tracking microscope for freely moving animals, the authors discover a population of place cells in the zebrafish brain and demonstrate that a non-amniote brain is capable of integrating alloth...

nature.com