Curious how cryo-ET reveals cells in 3D? Join the Harvard Cryo-EM Center & Thermo Fisher Dec 7–8 at HMS for our first cryo-ET workshop: top speakers, methods workshops, posters, a facility tour & pub trivia. Only 80 seats! Register by Dec 1: forms.cloud.microsoft/r/GfTQ7kg9Yx #CryoET
Haixia Zhou
@haixia.bsky.social
Structural biologist and post-doc in the Brown Lab @harvardmed.
First day here and I brought a paper. Three years of cryo-FIB-ET on human airway cells, nine proteins identified and two new PCD genes at the end of it. Grateful to the teams in Munster (Omran Lab), Boston (@alanbrownhms.bsky.social, Hawkins Lab) and Geneva (@centriolelab.bsky.social).
Millions of beating cilia keep airways clean. At the base of each is the transition zone (TZ), a gate that controls which proteins enter and leave. In our paper out today in Science, we used cryo-FIB-ET to image the TZ inside human airway cells www.science.org/doi/10.1126/...