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Glucosamine supplementation is associated with accelerated Alzheimer's Disease progression and worsened survival. These results establish hyperglycosylation as a pathological driver of AD and highlight glycan metabolism as a target in the fight against AD. www.nature.com/articles/s42...

Hyperglycosylation is a metabolic driver of Alzheimer’s disease - Nature Metabolism

Through spatial multiomics, spatial stable isotope tracing and retrospective cohort analyses, this study identifies hyperglycosylation as a driver of Alzheimer’s disease and a promising therapeutic ta...

nature.com

Researchers have set a new ambient-pressure superconductivity record of 151 K (-188 °F) By treating pressure as a temporary environment rather than a permanent structural tool, researchers stabilized a 151 K (-188 °F) superconducting state at atmospheric pressure. www.asme.org/topics-resou...

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Fusogen-induced recovery of spinal cord function after being severed This study reports the effects of a fusogen sealant, composed of polyethylene glycol and chitosan By the end of the study, all animals could assume an upright posture & walk Study: journals.plos.org/plosone/arti...

Fusogen-induced recovery of spinal cord function and morphology after complete transection

Spinal cord injury is a critical issue in neurosurgery, lacking established clinical methods for functional restoration. This study reports the effects of a fusogen sealant, composed of polyethylene g...

journals.plos.org

A 481-meter-high landslide-tsunami in an Alaska fjord frequented by cruise ships At 5:26 a.m. Alaska Daylight Time on 10 August 2025 (13:26 UTC), a large landslide (>64 × 106 m3) collapsed one vertical kilometer onto South Sawyer Glacier and into Tracy Arm fjord www.science.org/doi/10.1126/...

A 481-meter-high landslide-tsunami in a cruise ship–frequented Alaska fjord

Early in the morning of 10 August 2025, a >64 × 106–cubic meter landslide struck Tracy Arm fjord in Alaska. The landslide was preconditioned by glacial retreat caused by climate change. The resulting ...

science.org

Study: Adults ages 80+ with unusually fast gait had about half the cognitive impairment risk as others Earlier research that people 80+ who walk as fast as younger people 30 had a lower burden of disease, a healthier lifestyle, and a younger biological age. www.neurology.org/doi/10.1212/...

Cognitive Aging and Brain Health | Neurology

Background and ObjectivesSuper movers are individuals aged ≥80 years with gait speeds ≥1.5 SDs above age- and sex-adjusted means. Super movers tend to have lower prevalence of chronic medical conditio...

neurology.org

JAMA releases Covid vaccine study the acting CDC director blocked from the CDC MMWR The findings suggest Covid vaccines reduced the likelihood of a Covid-related visit to the ER or urgent care by 50% and of hospitalization for Covid by 55% last fall and winter. jamanetwork.com/journals/jam...

Interim Estimated Effectiveness of 2025-2026 COVID-19 Vaccines in Adults

This case-control study estimates vaccine effectiveness of 2025-2026 COVID-19 vaccines among adults with COVID-19–associated emergency department or urgent care encounters and COVID-19–associated hosp...

jamanetwork.com

Precision indole skeletal editing for single-carbon replacement Precision skeletal editing is a transformative approach in synthetic chemistry Skeletal editing directly remodels the core framework through single-atom insertion, deletion, or swapping. www.science.org/doi/10.1126/...

Precision indole skeletal editing for single-carbon replacement

Indole is widely present in pharmaceuticals and natural products. In this work, we report an intramolecular skeletal editing reaction of tryptamine derivatives enabled by photoreaction of a pendant am...

science.org

Sexism is often a stronger predictor of political attitudes than a voter’s actual gender. A voter’s level of sexism is a significant predictor of their political attitudes and voting choices. Prejudice shape support for right-wing candidates & climate policy. academic.oup.com/poq/article-...

Sexism as a Predictor of Political Attitudes and Voting Behavior: A Systematic Review

Abstract. The election of Donald Trump in 2016 inspired sudden interest in the association between voters’ sexism and voting behavior. Existing research sh

academic.oup.com