Heide Ford Lab

@heidefordlab.bsky.social

Professor and Chair, Department of Pharmacology University of Colorado Anschutz Medical Campus Cancer biologist, metastasis researcher interested in tumor cell plasticity Colorado and outdoor enthusiast 🏔️🏔️☀️

Sharing this new review written by two talented trainees from the Ford lab, Sheera Rosenbaum and Kaiah Fields. @kaiahfields.bsky.social

PLOS Biology@plosbiology.org · last yr.

The ability of #cancer and immune cells to change their phenotype contributes to tumor progression and therapy resistance. @heidefordlab.bsky.social explores the mutual plasticity of cells in the tumor microenvironment and why this matters for the development of therapies 🧪 plos.io/4774Y7a

Excited to share a new study from the Ford lab: EYA3 regulation of NF-κB and CCL2 suppresses cytotoxic NK cells in the premetastatic niche to promote TNBC metastasis | Science Advances www.science.org/doi/10.1126/... Congratulations to Sheera Rosenbaum and Connor Hughes, as well as all co-authors!

EYA3 regulation of NF-κB and CCL2 suppresses cytotoxic NK cells in the premetastatic niche to promote TNBC metastasis

EYA3 promotes evasion of cytotoxic NK cells to enable metastasis, highlighting a therapeutic target in metastatic breast cancer.

science.org

So proud of Ford lab members who have recently defended their theses (Connor Purdy and Art Wolin) and matched into the Duke internal medicine residency (Connor Hughes, MSTP). It’s been a busy couple of months for the lab, but nothing is more special than watching the success of your trainees!

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