🚨🚨 New Publication Alert!!! 🚨🚨 The Gardinier Lab just published new research in the Journal of Bone and Mineral Research @asbmr.bsky.social! They demonstrated the effects of ARHGEF3 deletion on #bone formation and resorption! Check it out here: academic.oup.com/jbmr/advance...

ARHGEF3 Deletion Increase Bone Formation and Suppresses Bone Resorption in Adult Mice

Abstract. ARHGEF3 (also known as XPLN) is a Rho guanine nucleotide exchange factor that activates RhoA/B. Variants in the ARHGEF3 gene are associated with

academic.oup.com

@orthoengineer.bsky.social representing the home team at the #TERMISAM2025 meeting being held in #Detroit right now!

Kevin Baker@orthoengineer.bsky.social · 11mo ago

Who says PIs dont stand by their posters!? Presenting our ACL reconstruction research at #TERMISAM2025 in #Detroit.

Monthly #OARSI ECI Publication: @amandality.bsky.social and her team identified miR-126-3p as a promising biomarker for knee #OA. It reduces angiogenesis and mitigates disease severity, supporting its potential as a therapeutic target.

Exciting research presented by @orthoengineer.bsky.social at the ICRS meeting in Boston. More innovation in the #osteoarthritis and #ACL reconstruction space brought to you by @hfhs-bjc.bsky.social researchers! #orthosky

Kevin Baker@orthoengineer.bsky.social · 12mo ago

Fantastic time at the 18th World Congress of the International Cartilage Regeneration & Joint Preservation Society in Boston. Presented our work on IDO-1 and #Kynurenines in #osteoarthritis, and a project focused on improved healing in #ACL reconstruction. As always - huge thanks to the team!

🚨🚨 New Publication Alert: The Ali Lab published a review on advancements in genomics, genetics, and epigenetics of #osteoarthritis. Fantastic work Thomas Wilson, Madhu Baghel and @amandality.bsky.social! www.oarsijournal.com/article/S106...

Osteoarthritis year in review 2025: Genetics, genomics, and epigenetics

This review provides an overview of the work performed in the realms of genetics, genomics and epigenetics in osteoarthritis (OA) research over the past year.

oarsijournal.com

🎉 Congrats to the 2026 ORS Collaborative Exchange Grant recipients! These awards support collaborations between #musculoskeletal researchers at different institutions. Read their research project summaries: https://www.ors.org/ors-collaborative-exchange-grants/

🚨🚨New publication alert! @orthoengineer.bsky.social and colleagues published a study examining the ability to use endogenous MSCs to mitigate lumbar intervertebral disc degeneration. My back hurts less after reading the paper! #spine #regenerativemedicine #stemcells

Kevin Baker@orthoengineer.bsky.social · last yr.

Sharing our new publication on the topic of recruiting endogenous, pharmacologically-mobilized MSCs to degenerative lumbar intervertebral discs. Early results but step in the right direction! 1/ journals.sagepub.com/doi/full/10....

🚨🚨New publication alert! The Ali Lab @amandality.bsky.social ‬ in the @hfhs-bjc.bsky.social uses sequencing to profile microRNAs in early-stages of both osteoarthritis and rheumatoid arthritis! Now published in Scientific Reports ‪@natureportfolio.nature.com‬, read it here: rdcu.be/eylic

Circulating microRNA profiles in early-stage osteoarthritis and rheumatoid arthritis

Scientific Reports - Circulating microRNA profiles in early-stage osteoarthritis and rheumatoid arthritis

rdcu.be

The Henry Ford Health Bone & Joint Center has a storied history with microCT imaging of MSK tissues, thanks primarily to Dr. Yeni's group. Today we took a large leap forward with the installation of a brand new Scanco MicroCT-90 system! #orthopaedics #imaging #bone #cartilage

Now accepting applications for the ORS/RJOS Young Female Investigator Grant! Includes a 1k travel stipend from @RJOSociety & free registration to the 2026 RJOS and ORS Annual Meetings. Open to early-career female #orthopaedic researchers. Apply by Aug 25: bit.ly/3qOTbYu

Members of the Bone & Joint Center had a great time sharing and learning about musculoskeletal research at @michiganstateu.bsky.social and @henryfordhealth.bsky.social during the HFH+MSU Musculoskeletal Research Retreat. Our Chairman @shouldergeek.bsky.social delivered inspiring opening remarks!

Strong work Thomas and the Ali Lab!

Amanda Ali@amandality.bsky.social · last yr.

Excellent presentation by Research Associate Thomas Wilson from the Ali Lab @hfhs-bjc.bsky.social at the 9th annual Musculoskeletal Health Symposium @uofmichigan.bsky.social! Grateful for the opportunity to share our research on the podium and to connect with fantastic MSK Twitter colleagues IRL.

New Publication Alert! Bone & Joint Center researchers @orthoengineer.bsky.social and @eriebaker.bsky.social along with colleagues from several institutions just published a study in the American Journal of Sports Medicine on a new regenerative medicine strategy to improve rotator cuff repair!

Kevin Baker@orthoengineer.bsky.social · last yr.

Our paper on enhancing the repair of #RotatorCuff tears using pharmacologic methods to recruit endogenous MSCs is out in AJSM today! The project was fun, but I can't say enough about my amazing co-authors. Read it here: journals.sagepub.com/doi/10.1177/...

Another fantastic @henryfordhealth.bsky.social Research Symposium in the books! Inspiring to hear about all of the awesome research from across the campus. Equally amazing to hear from @boneybonebone.bsky.social of the Yeni Lab @hfhs-bjc.bsky.social talking about facet joint measurement via DTS!

New paper from Dr. Yeni, @boneybonebone.bsky.social, et al. just published in @jbiomech.bsky.social! The team used digital tomosynthesis (DTS) to quantify spinal facet joint width. They also showed that this technique can be used in vivo to dynamically observe human facet joint loading! #Orthosky

Check out the latest Nature Communications manuscript from Dr. Ali in the Bone & Joint Center! Establishing circulating microRNA-126-3p as a biomarker in human knee #osteoarthritis and demonstrating an angiogenesis-driven protective effect in an animal model. Small RNAs with big implications!

Amanda Ali@amandality.bsky.social · 2y ago

Excited to share our work on the small but mighty microRNA-126-3p in @naturecomms.bsky.social! We found this microRNA is elevated in four knee osteoarthritis cohorts and show in an animal model that it reduces the severity of knee osteoarthritis - at least in part via angiogenesis. rdcu.be/ebycj