Happy to see our work describing an avidity mechanism of extracellular BMP regulation out. A great team effort from all involved!

Gareth Moore@garethmoore.bsky.social · 5mo ago

Over the moon to see this work from my PhD finally published in Development! Using a combination of structural biology and genetics we identify an avidity-driven mechanism of BMP signal control in the extracellular space. (1/11)

It's Postdoc Appreciation Week - thanks to all the fabulous postdocs in the Ashe lab for their hard work and collegiality!

Our work on germline stem cell cytonemes and BMP signalling is finally published! A great team effort from the Ashe lab, @wilcocksonscott.bsky.social and @shukryjhabib.bsky.social. www.pnas.org/doi/epdf/10....

Biblical!

Fun @mcf-uom.bsky.social celebration event today. Nice to see team LEAF being recognised for all the hard work in helping the MCF labs get LEAF gold awards. And good to celebrate Ali’s paper again!

Just seen a local post box with a crocheted topper with 22 bees remembering each victim of the Manchester Arena bombing ❤️

Think we’ve captured a hedgehog courtship ritual on camera last night. Fingers crossed for some hoglets in a couple of months

Not sure what the collective noun is for tadpoles

Really excited about this collaboration!

Yad Ghavi-Helm@yghavi.bsky.social · last yr.

Honored and extremely grateful to see our project in collaboration with @hilaryashe.bsky.social and @hilsawh.bsky.social awarded an #HFSPReseachGrant @hfspo.bsky.social Stay tuned for exciting job offers!

Sog translation live in the embryo - so beautiful! Work done in collaboration with @markashe.bsky.social and @mrattray.bsky.social

Journal of Cell Science@jcellsci.bsky.social · last yr.

In their Tools and Resources article, Alastair Pizzey, @hilaryashe.bsky.social and colleagues use the SunTag system to interrogate the developmental regulation of mRNA translation in Drosophila. Highlight: journals.biologists.com/jcs/article/... Article: journals.biologists.com/jcs/article/...

We are hiring! A postdoc position is available in the lab studying gene expression dynamics in Drosophila embryos, as part of a larger research effort in collaboration with @mrattray.bsky.social 🧬🔬🪰 Full details are in the ad: www.jobs.manchester.ac.uk/Job/JobDetai...

Our exciting garden visitor is back. Shame I was sleeping at the time 🦡

Fun paper celebrations across the developmental biology and @mcf-uom.bsky.social groupings this afternoon. Celebrating our latest paper and papers from the @brainotopia.bsky.social @lovegrovelab.bsky.social, Herbert, Manning, Bennett and Papalopulu labs. Congrats to all!

Our new paper describes how SunTag imaging of mRNA translation can be used to study ribosome pausing in development. We also adapt the system to study translation of a secreted protein. Work done in collaboration with @mrattray.bsky.social and @markashe.bsky.social doi.org/10.1242/jcs....

Exploiting the SunTag system to study the developmental regulation of mRNA translation

The ability to quantitatively study mRNA translation using SunTag imaging is transforming our understanding of the translation process. Here, we expand the SunTag method to study new aspects of transl...

doi.org

Looks like we have a new couple moving in

Lots of frogs hanging around our pond. Hopefully there will be some frog spawn soon 🐸

Calling all developmental biologists in the north of England, there's an interesting meeting coming up

Is there more to defining the eve stripes in the Drosophila embryo than just transcriptional regulation? We provide evidence that spatially regulated mRNA decay is also important.

Magnus Rattray@mrattray.bsky.social · 2y ago

Nice new paper from Jennifer Love and @hilaryashe.bsky.social lab members shows how mRNA decay is spatially and temporally regulated, ramping up at the edges of stripes in early drosophila embryos, with mRNAs increasingly localising to P-bodies for degradation www.biorxiv.org/content/10.1...