Hilda Bastian

@hildabast.bsky.social

Scientist (PhD she/her), writer, cartoonist. 🦘 Tracking NextGen Covid Vaccines at https://vaxtracker.wordpress.com/ Personal newsletter: Living With Evidence https://hildabastian.wordpress.com/

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Hilda Bastian@hildabast.bsky.social · last wk.

A New Chapter It's wattle time here in country Victoria, and the bees are ecstatic! All that glorious yellow cheers up the middle of winter no end. It's such an optimistic color. I'm feeling optimistic, too, even though this month did not go as planned. That began, as disruptions so often do, with…

A New Chapter It's wattle time here in country Victoria, and the bees are ecstatic! All that glorious yellow cheers up the middle of winter no end. It's such an optimistic color. I'm feeling optimistic, too, even though this month did not go as planned. That began, as disruptions so often do, with…

A New Chapter

It's wattle time here in country Victoria, and the bees are ecstatic! All that glorious yellow cheers up the middle of winter no end. It's such an optimistic color. I'm feeling optimistic, too, even though this month did not go as planned. That began, as disruptions so often do, with an unexpected email. This one was from PLOS, the home of my blog, …

hildabastian.wordpress.com

A *bumper* month of nextgen Covid vax clinical trial news: — Results of 2 clinical trials for mucosal vaccines, including Vaxart's oral vax — Another mucosal vaccine is going into clinical trial, and 4 others are fully recruited or completed ...1/3 absolutelymaybe.plos.org/2026/07/29/b...

Bumper Month of Clinical Trial News to Ring Out This Vax Series - Absolutely Maybe

Before I get to the bumper crop of recent clinical trial news, there is news about this monthly update. This is the…

absolutelymaybe.plos.org

My monthly update on next generation Covid vaccines is online now @plos.org — with a new streamlined structure I hope makes it easier & quicker to read. News on a major UK grant supporting a UK/US collaboration on a vax from Stanford Uni, plus ...1/2 absolutelymaybe.plos.org/2026/06/29/m...

More Trials Recruiting and Other NextGen Covid Vaccine News - Absolutely Maybe

June was a relatively slow news month for next generation Covid vaccine development. So I took the opportunity to simplify the structure…

absolutelymaybe.plos.org

My monthly update on next generation Covid vaccines is online now @plos.org — with a new streamlined structure I hope makes it easier & quicker to read. News on a major UK grant supporting a UK/US collaboration on a vax from Stanford Uni, plus ...1/2 absolutelymaybe.plos.org/2026/06/29/m...

More Trials Recruiting and Other NextGen Covid Vaccine News - Absolutely Maybe

June was a relatively slow news month for next generation Covid vaccine development. So I took the opportunity to simplify the structure…

absolutelymaybe.plos.org

A big month for next generation Covid vaccine trials! — Details of an exciting trial in Tanzania for an intranasal vax for low-resource communities—results may come soon; — An overview of the Covid human challenge studies, as one reaches a milestone .... 1/2 absolutelymaybe.plos.org/2026/05/31/a...

A Bumper Month of Clinical Trial News (NextGen Covid Vax Update) - Absolutely Maybe

It was a big month for clinical trials of next generation Covid vaccines. An exciting phase 1/2 trial in Africa for an…

absolutelymaybe.plos.org

A big month for next generation Covid vaccine trials! — Details of an exciting trial in Tanzania for an intranasal vax for low-resource communities—results may come soon; — An overview of the Covid human challenge studies, as one reaches a milestone .... 1/2 absolutelymaybe.plos.org/2026/05/31/a...

A Bumper Month of Clinical Trial News (NextGen Covid Vax Update) - Absolutely Maybe

It was a big month for clinical trials of next generation Covid vaccines. An exciting phase 1/2 trial in Africa for an…

absolutelymaybe.plos.org

A bit of medical history to distract from a hot day. My article in @uk.theconversation.com tells a favourite story from BEYOND BELIEF: how a remarkable randomised trial showed conventional wisdom on bedrest was wrong and helped inspire evidence-based medicine. theconversation.com/how-a-remark...

How a remarkable trial on bedrest during the Korean war helped lead to evidence-based medicine

How a bedbound patient and a 73-page study changed the way doctors make decisions.

theconversation.com

A slow month for next generation Covid vax results, but a big month for clinical trial news. New clinical trial for intranasal vax starting in the US, & another expanding to another 2 cities. A "variant-proof" vax going into phase 2a trial in Germany: absolutelymaybe.plos.org/2026/04/30/a...

Another Intranasal Covid Vaccine Starting in the US (NextGen Vax Monthly Update) - Absolutely Maybe

This month intranasal and inhaled versions of a Covid vaccine are heading into a phase 1 trial in the US. The vaccine…

absolutelymaybe.plos.org

“No single raindrop…” "No single raindrop believes it is to blame for the flood." This is a line from a poster I used to have in my office. It popped into my head this week when I was in a queue to fuel my car. We've had shortages around here—not because the country didn't have enough, but because…

“No single raindrop…”

"No single raindrop believes it is to blame for the flood." This is a line from a poster I used to have in my office. It popped into my head this week when I was in a queue to fuel my car. We've had shortages around here—not because the country didn't have enough, but because panic buyers have been draining supplies.

hildabastian.wordpress.com

New feature: Which nextgen Covid vaxes are advancing the most? I highlight 3 in mid- to late-stage trials with manufacturers—including a "universal" Covid vax & a mucosal one—and another 6 vaccines. Plus more trial results & 10 preclinical reports: absolutelymaybe.plos.org/2026/04/02/a...

Accelerating Development for Some NextGen Covid Vaxes (Update No 39) - Absolutely Maybe

Several next generation Covid vaccines are now advancing into mid- or late-stage trials. So this month, I have started a new section—a…

absolutelymaybe.plos.org

In February 2021, a town in Brazil showed up for a groundbreaking randomized Covid vax trial, providing evidence of population effects of mass vaccination in a pandemic. My latest @plos.org post digs into this exciting precedent & why it matters: absolutelymaybe.plos.org/2026/03/28/a...

A Unique Pandemic Control Trial - Absolutely Maybe

When I was young, while I understood pandemics that kill millions could happen in theory, I really thought they were a thing…

absolutelymaybe.plos.org

In February 2021, a town in Brazil showed up for a groundbreaking randomized Covid vax trial, providing evidence of population effects of mass vaccination in a pandemic. My latest @plos.org post digs into this exciting precedent & why it matters: absolutelymaybe.plos.org/2026/03/28/a...

A Unique Pandemic Control Trial - Absolutely Maybe

When I was young, while I understood pandemics that kill millions could happen in theory, I really thought they were a thing…

absolutelymaybe.plos.org

News-packed update on nextgen Covid vaccines this month at my @plos.org blog: - Preclinical results for an intranasal "universal" vaccine that provided some protection from coronaviruses, H1N1 flu, some bacterial infections, and an asthma allergen... 1/2 absolutelymaybe.plos.org/2026/03/01/p...

Progress for "Universal" Vaccine & More NextGen Covid Vax News (Update No 38) - Absolutely Maybe

This month, there are phase 2 results for a self-amplifying mRNA vaccine from Japan—and that vaccine’s developers have recently completed a phase…

absolutelymaybe.plos.org

News-packed update on nextgen Covid vaccines this month at my @plos.org blog: - Preclinical results for an intranasal "universal" vaccine that provided some protection from coronaviruses, H1N1 flu, some bacterial infections, and an asthma allergen... 1/2 absolutelymaybe.plos.org/2026/03/01/p...

Progress for "Universal" Vaccine & More NextGen Covid Vax News (Update No 38) - Absolutely Maybe

This month, there are phase 2 results for a self-amplifying mRNA vaccine from Japan—and that vaccine’s developers have recently completed a phase…

absolutelymaybe.plos.org