HillerLab

@hillerlab.bsky.social

Group of Prof Sebastian Hiller. Structural Biology Research Group. Unravelling Biomolecular Mechanisms. (run by students)

Last day for our summer student Shreyan Datta, who has done great work during his one and a half months in our lab working on the Hsp70 functional cycle! If you are looking for a PhD student in the next few months, Shreyan Datta will be a great fit for any lab!

Thrilled to share our new method in-cyclo NMR that lets us watch molecular machines in action — decoding molecular machine kinetics with atomic precision and exceptional time resolution in one go! 🚀 Check it out: doi.org/10.1038/s414... #NMR #StructuralBiology

Mechanism of ATP hydrolysis in the Hsp70 BiP nucleotide-binding domain - Nature Communications

Mas et al introduce in-cyclo NMR to quantify all states and kinetic steps of Hsp70 chaperones ATPase cycle. In-cyclo NMR will enable studies of other molecular machines at an unprecedented level of de...

doi.org

HillerLab@hillerlab.bsky.social · last yr.

Introducing in-cyclo NMR, a breakthrough method led by first author @masgu.bsky.social at @biozentrum.unibas.ch! This method combines high-resolution NMR with ATP regeneration & phosphate removal to resolve kinetics & dynamics of molecular machines - all in one experiment! doi.org/10.1038/s414...