Zongzhao Zhai
@immuno-physiology.bsky.social
PI studying innate immunity and physiology. Interested in Drosophila genetics, host defense, mTORC1 signaling, translational regulation, gut homeostasis, and also a bit mosquito biology. FInd us https://yinyulong.hunnu.edu.cn/info/1076/1234.htm
Excited to share our work reporting that fly Lsp2 acts as a nutrient-induced physiological factor that amplifies mTORC1 output in TOP mRNA translation and regulates lifespan. www.nature.com/articles/s41...
Lsp2 links mTORC1 to TOP mRNA translation and lifespan in Drosophila - Nature
In Drosophila, the protein Lsp2, which is induced by dietary essential amino acids, is a key physiological effector of mTORC1, and mutant flies that lack the Lsp2 gene exhibit reduced translation of T...
nature.com
Such a pleasure to see our work, and our companion paper from Dr. Obata, highlighted by Dr. Linda Partridge! www.nature.com/articles/s41... www.nature.com/articles/s41...
Nature@nature.com · 2w agoA fruit-fly protein thought only to store amino acids in fact responds to nutritional deficiency in both development and adulthood, resulting in lifespan extension go.nature.com/4d6rRdo
A fruit-fly protein thought only to store amino acids in fact responds to nutritional deficiency in both development and adulthood, resulting in lifespan extension go.nature.com/4d6rRdo
Surprising protein links dietary restriction to increased lifespan in flies
A fruit-fly protein thought only to store amino acids in fact responds to nutritional deficiency in both development and adulthood, resulting in lifespan extension.
go.nature.com