IMPORTANT at the Nordic #BreastCancer Meeting 2026! IMPORTANT was presented as an example of a #PragmaticClinicalTrial designed to generate evidence relevant to everyday oncology practice. The right dose, for the right patient, at the right time! #EUCancerMission nordiskt-brostcancermote.mkon.se

Nordiskt Bröstcancermöte

Nordiskt Bröstcancermöte

nordiskt-brostcancermote.mkon.se

The IMPORTANT Patient Companion was presented by Maryam Yeganeh (FHNW) at AI Open House Basel, an event with more than 100 participants Showcasing patient-centred healthcare navigation & decision-making through digital innovation #IMPORTANTProject #DigitalHealth #PatientCentredCare #EUCancerMission

IMPORTANT at the Nordic Congress on Breast Cancer 2026! Prof. Antonis Valachis presented IMPORTANT as an example of treatment optimisation during his talk "Treatment reduction–safe or risky?" The right dose, for the right patient, at the right time #IMPORTANTProject #BreastCancer #EUCancerMission

IMPORTANT Newsletter #21 is out! All 16 trial sites are open for recruitment, with 146 patients included and 134 randomized as of 31 August 2026 Read the latest updates from the IMPORTANT project important-project.com #IMPORTANTProject #HorizonEurope #BreastCancer #ClinicalTrials #GeriatricOncology

📢 New publication from #IMPORTANTProject! The partner University of Patras has published new research exploring how digital twins, mechanistic modelling & AI can support more personalised approaches in geriatric oncology & care for older people with cancer. 🔗 www.frontiersin.org/journals/art...

Frontiers | From mechanistic models to artificial intelligence: exploring the potential of digital twins in geriatric oncology

This survey explores how machine learning and artificial intelligence (AI) can be integrated with mechanistic models to create more accurate, dynamic, predic...

doi.org

📣 IMPORTANT Newsletter #19 is out! 13 sites are open, 133 patients have been included, 124 randomized & 3 new Greek sites are preparing to recruit. Recruitment continues until April 2027 🌐 important-project.com #IMPORTANTTrial #GeriatricOncology #BreastCancerResearch #CancerMission #HorizonEurope

📢 New #IMPORTANT Project publication: a multinational survey reveals wide variation in CDK4/6 inhibitor dosing for older patients with metastatic breast cancer—highlighting the need for stronger clinical evidence. 🔗 www.geriatriconcology.net/article/S187... #GeriatricOncology #BreastCancer

CDK4/6 inhibitor dose patterns among older patients with metastatic breast cancer: A multinational survey study

Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) combined with endocrine therapy (ET) improve outcomes in HR+/HER2− metastatic breast cancer (MBC) [1–5]. However, older adults remain underrepresented ...

geriatriconcology.net

📢 IMPORTANT Newsletter #18 is out! Updates on recruitment, safety monitoring, and our 5th consortium meeting in Helsinki. Read the full newsletter attached. Funded by the EU under Horizon Europe GA No. 101104589. #MPORTANTProject #BreastCancer #HorizonEurope #EUCancerMission #GeriatricOncology

The IMPORTANT Project consortium has successfully completed its 5th project meeting in Helsinki, Finland. Partners came together to review progress, exchange updates and align on the next phase of work, with discussions covering recruitment, dissemination, research outputs, pilots and ethics.

📢 IMPORTANT Trial Newsletter #17 is out! Updates include: ✅ 13 sites open for recruitment ✅ 118 patients included, 109 randomized ✅ Latest news on adaptive trial design and interim analysis Funded by the EU under Horizon Europe GA No. 101104589. UK participant supported by UKRI.

The IMPORTANT trial was presented at the EUnetCCC symposium “Innovating Cancer Care Through De-escalation Studies” in Amsterdam, contributing to discussions on improving cancer treatment through high-quality de-escalation studies #CancerResearch #BreastCancer #ClinicalTrials #HorizonEurope #EUnetCCC

🚀 #IMPORTANTTrial update: 101 patients enrolled so far, with 13 clinical sites currently open for recruitment. Together, we are generating evidence to improve treatment for older people with breast cancer. #BreastCancer #ClinicalTrials #GeriatricOncology #ClinicalTrials #EUfunded #HaDEA #HorizonEU

🎥 New video: Why dose optimisation matters for older people with advanced breast cancer. The IMPORTANT project is studying CDK4/6 inhibitor dosing strategies to improve tolerability, quality of life, and shared decision-making in treatment. #IMPORTANTproject #BreastCancer #HorizonEurope

The #IMPORTANTProject will join the #EUnetCCC Symposium on Cancer Treatment De-escalation 📅 5–6 March 2026 📍 NKI, Amsterdam Proud to contribute to the discussion on personalised dose optimisation for older patients with advanced HR+/HER2- breast cancer #DeEscalation #HorizonEurope #EUCancerMission

🎯Optimising treatment for older patients with metastatic #BreastCancer Watch here: lnkd.in/dGzPDhBv 🔬The #IMPORTANTProject aims to optimise CDK4/6 inhibitor dosing through a multinational clinical trial integrating geriatric assessment–based strategies 🎗️Older patients deserve evidence-based care

🎉 New paper accepted at PERSUASIVE 2026! Researchers in the EU Horizon Europe IMPORTANT Project explored why older adults hesitate to join decentralised breast cancer clinical trials. Key message: patient support must be local, personalised & human-centred. 📍 Hakodate, Japan | March 10–13, 2026

The IMPORTANT EU Project contributes to the Mission Cancer Cluster on Citizen Engagement, working with partner projects: LIVERATION, SAGITTARIUS, PragmaTIL, CARE1, PRIME-ROSE, DE-ESCALATE, IntReALL2020, LEGATO, IMPACT-AML, SALVOVAR, STREXIT2 #MissionCancer #CitizenEngagement #HorizonEurope #HADEA

Newsletter #15 The latest update is out! So far, 93 patients enrolled, all 13 sites active and preparations underway for a toxicity-driven interim analysis at 100 patients. The project continues to advance geriatric assessment–guided dosing of CDK4/6 inhibitors for older patients with breast cancer

The IMPORTANT project was featured in two key events! At the 36th Panhellenic Congress of Hematologists, Christiana Markou presented on the EU AI Act and its clinical impact At EUC’s AI Month 2025, she joined a round-table on bringing AI into clinical practice 🇪🇺 Funded by the EU (GA 101104589)

Happening today: the EU Cancer Mission Conference on Advancing cancer care: personalised treatment and innovation Researchers, clinicians, policymakers, survivors & advocates are coming together to discuss the future of personalised cancer care and precision medicine across EU link.europa.eu/pm6k4d

At #ESMO25 in Berlin 🇩🇪, Prof Laura Biganzoli presented the #IMPORTANTtrial - advancing geriatric assessment for dose optimization in older breast cancer patients A step forward in personalizing cancer care for older adults #HorizonEurope #GeriatricOncology #BreastCancer #EUfunded #ClinicalResearch

The #IMPORTANTproject joined the 2nd #HorizonEurope Cancer Mission “Diagnosis & Treatment” Cluster Meeting in Berlin 🇩🇪 We shared actions on #CitizenEngagement & #AddressingInequalities in cancer care highlighting how we bring science closer to people. #MissionCancer #CancerResearch #HaDEA

The IMPORTANT Project at the ERN 2025 in Cyprus Eunomia Ltd represented the IMPORTANT project, raising awareness on breast cancer, prevention & health literacy Through interactive quizzes, participants learned about prevention, health literacy & empathy, sharing messages of hope and solidarity 💗

Our REWBAH'25 presentation is ongoing @maryam-yeganeh.bsky.social #important-project #horizon @fhnwinformatik.bsky.social

Samuel A. Fricker@samuelfricker.bsky.social · last yr.

We are very happy that our paper with Maryam Rabie Yeganeh has been accepted at REWBAH'25 👉 "One Size Doesn’t Fit All": Patient Support in a Decentralised Clinical Trial.

We are very happy that our paper with Maryam Rabie Yeganeh has been accepted at REWBAH'25 👉 "One Size Doesn’t Fit All": Patient Support in a Decentralised Clinical Trial.

Daniel Amyot@danielamyot.bsky.social · 2y ago

🚀 Call for Papers: REWBAH'25 – Sixth International Workshop on Requirements Engineering for #Well-Being, #Aging, and #Health – co-located with the 33rd IEEE International #RequirementsEngineering Conference (RE’25) 📅 Date: Sept. 1 or 2, 2025 📍 Valencia, Spain 🌐 sites.google.com/view/rewbah2...

🎥 New video out! Excited to share the story of the IMPORTANT Project-the mission, clinical goals & innovative approach to optimizing CDK4/6-inhibitor treatment for older patients with advanced breast cancer ▶️ Watch the video: play.mediaflow.com/ovp/17/72DFN... 🔗 Learn more: important-project.com