We're excited to sponsor the 77th London Biological Mass Spectrometry Discussion Group (LBMSDG) on 2 September at The Gordon Museum of Pathology, King's College London. Catch Applications Scientist, Dr Yana Demyanenko as she delivers the Opening Plenary at the event. Register: lnkd.in/djtnHig4

NOW PEER-REVIEWED: Emery-Corbin et al. compared 8 sample preparation methods across human serum, plasma, and rat plasma, identifying up to 2,726 human proteins and 3,767 rat proteins, with corona enrichment methods achieving the deepest coverage. Learn more: bit.ly/3RirGUI

An eight-workflow plasma proteomics benchmark, now peer-reviewed and published. Plus: single-cell drug response subtyping in cardiomyocytes, proteomic maps of iPSC-to-motor neuron differentiation, and de novo protein sequencing with a single archaeal protease. Read the full digest: bit.ly/4fF1Xh5

The best plasma proteomics workflow? It depends. Emery-Corbin et al. explain why

NOW PUBLISHED: Emery-Corbin et al. demonstrate that plasma workflow selection should match biological context, as different methods illuminate distinct protein subsections Plasma proteomics has advanc...

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Maximising instrument utilisation on an Orbitrap Astral takes more than a fast instrument. For Dr Juan Liu, mass spec lab manager at @hhmi-science.bsky.social Howard Hughes Medical Institute, the right column made it possible. Learn more about Aurora® Ultimate™ 25x150: bit.ly/4ykTWGE

Following the opening of its new UK facility, IonOpticks is expanding its US presence with local stock in Pennsylvania, faster fulfilment, North America-based applications support and dedicated regional expertise. Read the full release.

IonOpticks announces expanded US presence to bring products and support closer to North American researchers

IonOpticks today announces a further expansion of its global presence, with strengthened operations and customer support across the United States.The expansion improves access to IonOpticks’ advanced ...

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IonOpticks is proud to officially open a new purpose-built facility at Milton Park in Oxfordshire UK, expanding its global presence with local order processing, distribution, warehoused stock, commercial and scientific expertise, and a dedicated applications development laboratory. Read online:

IonOpticks opens UK-based facility to bring faster access, local expertise and application support closer to European researchers

IonOpticks' new facility, based in the Milton Park scientific precinct south of Oxford, brings together order processing and distribution, locally warehoused stock, administrative support, commercial ...

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Great to be at #SCP2026 at @northeasternu.bsky.social last week, witnessing the remarkable momentum in single-cell proteomics. Across countless fantastic oral presentations, we’re seeing where SCP is heading: deeper characterisation, higher throughput, & better quantitation across diverse workflows.

We're pleased to welcome Dr Denise Tran to IonOpticks as Applications Scientist, based in Oxford, UK. She'll support researchers with LC-MS proteomics workflows, applications and method development, and help optimise performance, troubleshoot challenges and get the best from IonOpticks columns.

Great to be at #BSPR2026 in Hinxton this week, supporting the UK's key proteomics gathering. On Monday, conference conversations continued at our Peaks & Pints event - it's been a pleasure connecting with so many of you. If you're still here today, stop by - we'd love to hear what you're working on.

We're excited to welcome Dr Anuar Makhmut to IonOpticks as a Field Application Specialist, supporting researchers across Europe. He'll be working directly with research teams to design, optimise, and implement proteomics workflows suited to their goals. It’s fantastic to have him on board.

As a mass spec lab manager at @hhmi-science.bsky.social Howard Hughes Medical Institute, Dr Juan Liu's focus is on pushing proteome coverage deeper. After switching to the Aurora® Ultimate™ 25x150 XT for both general proteomics and phosphoproteomics workflows, the results speak for themselves:

De novo antibody sequencing typically demands 4–6 parallel protease digestions to adequately cover hypervariable CDR regions. Pañeda et al. challenge that paradigm entirely. LC-MS/MS used an Aurora® Elite™ 15×75 XS column, an UltiMate 3000, and a SCIEX ZenoTOF 7600. Learn more: bit.ly/4eshTEd

Janssens et al. benchmark the timsUltra AIP for SCP: using an Aurora® Elite™ 15×75 CSI column + nanoElute 2, the team achieved a >2× increase in protein IDs at the single-cell level, with ~50% of the detected proteome identified exclusively on the new instrument. Learn more: bit.ly/4gF6Tog

The 9th Annual Single-Cell Proteomics Conference kicks off at @northeasternu.bsky.social in Boston next week and we’re proud to be supporting as a Gold Sponsor. Jarrod, Zac, and Haley are all behind the booth. Stop by to see how we can support your workflows - or to say hi! We’d love to connect.

Few spots left for Peaks & Pints, Hinxton edition. If you'll be at BSPR, stick around on Monday, July 13 for an evening of conversation and connection at The Red Lion Inn, just a 6-minute walk from Hinxton Hall Conference Centre. Secure your complimentary, catered spot: bit.ly/4opQJRz

When your research involves thousands of glycoproteoforms, you need columns you can count on. To Dr. Tim Veth, postdoctoral researcher at the University of Washington, one Aurora column lasting several months of high performance was all the evidence he needed. Learn more: bit.ly/4nrMzad

Day 1 of the SEMM Workshop "The Proteomics Revolution: Advancing Science and Society" is wrapped up, and it's been a brilliant start to what promises to be a memorable few days in Milan. If you're here, come find us - Britta and Darren would love to connect.

Zhemkov et al. applied an exploratory, global protein identification approach across a 60-day iPSC-to-motor neuron differentiation protocol, using Aurora® Rapid™ 5x75 CSI columns on a timsTOF Ultra 2 to achieve ~20% greater sensitivity and ~175% more low-abundance protein detections. bit.ly/4aJKPFi

We're thrilled to welcome Dr Yana Demyanenko to the IonOpticks team as an Application Scientist, based in the UK. She'll help researchers get the most out of their LC-MS proteomics workflows. Outside the lab, Yana is an avid DIYer, making things from cakes to dresses to garden landscapes.

What happens to a neuron as it develops an Alzheimer's tangle? Single-cell proteomics has answers in the June 2026 Publication Digest | Plus glycogen ubiquitination, stress granule proteomics in single cells, and plasma workflow benchmarking with Aurora Series® columns Learn more: bit.ly/4oMipQV

What happens to a neuron as it develops an Alzheimer's tangle?

Single-cell proteomics has answers in the June 2026 Publication Digest | Plus glycogen ubiquitination, stress granule proteomics in single cells, plasma workflow benchmarking with Aurora Series® Narro...

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Most virtual cell models tell you what a cell is instructed to do, not what it really does. That's the gap Dr Zilu Ye is working to close. In our spotlight, Zilu talks single-cell proteomics, the result nobody believed, & why the biggest breakthroughs may arrive sooner than expected. bit.ly/4b8dOCS

From proof of concept to platform: How Dr. Zilu Ye is scaling single-cell proteomics for the real world

Dr. Zilu Ye, Principal Investigator at the Institute of Systems Medicine at the Chinese Academy of Medical Sciences, has spent his career developing mass spectrometry–based proteomics tools that don’t...

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Foiani et al. from the @ukdri.ac.uk shed light on Alzheimer's disease brain tissue using single-neuron proteomics, pairing an Aurora® Elite™ 15×75 CSI column with an Evosep One and timsTOF Ultra 2. Learn more: bit.ly/4xvASoJ

A recent @sciex.bsky.social technical note benchmarks the ZenoTOF 8600 system for short-gradient, high-throughput label-free quantitative (LFQ) proteomics. Chromatography performed on an ACQUITY UPLC M-Class paired with an Aurora® Ultimate™ 25x75 XS column for nanoflow analyses. bit.ly/4vZajqn

Dr @mari-mardamshin.bsky.social, postdoctoral fellow in Assoc Prof Emma Lundberg's lab at Stanford, works at the frontier of spatial proteomics, where column robustness is crucial - especially with low-input samples. Aurora Series® columns help make that work possible. Learn more: bit.ly/3IELayn

A new @sciex.bsky.social technical note demonstrates significant improvements in label-free quantitation (LFQ) proteomics using ZT Scan DIA 3.0 on the ZenoTOF 8600 system, which was paired with an ACQUITY UPLC M-Class System and an Aurora® Ultimate™ 25x75 XS column. Learn more: bit.ly/4oAy45V

On the final afternoon of the 74th MSSJ Annual Conference on Mass Spectrometry in Yokohama, our Sweets Seminar wrapped up with 80 attendees - a wonderful turnout, and a great energy to end the conference on. Even if it was testing the limits of Fabrice’s conversational Japanese!

Davison et al. coupled nanocapillary sampling with LC-MS for the first time to profile stress granule proteins from individual live cells, bypassing the limitations of bulk purification. Used Vanquish Neo, Aurora® Rapid™ 8×75 XT column, & Orbitrap Astral. Learn more: bit.ly/3PYy6HQ

We’re proud to support the @ukbspr.bsky.social BSPR Annual Scientific Meeting in Hinxton next month. Attending? We'd love to see you at Peaks + Pints on Monday, July 13 at The Red Lion Inn from 07:30pm, a short walk from the conference venue: bit.ly/4ose7xT

Last week, our UK team had the pleasure of hosting Fintiede Solutions Solutions, IonOpticks' local distribution partner, in person at our new facility. Of course, no meeting is complete without a proper spread, including the cultural exchange that is sharing a jar of Vegemite. Or is it Marmite?

Luke Gamon, Asst Prof at @ucph.bsky.social, built a spatial proteomics workflow from standard lab equipment: PCR tubes, centrifuges, basic plastics. When a single Aurora column can handle 2,500 injections and still perform, that kind of longevity changes what's feasible. Learn more: bit.ly/4ulX2XL