Our work on the role of the proteasome in developmental tempo is out!!!! 🐭⌛️👤⏳ Six years after identifying an association between protein stability and developmental tempo, we now demonstrate a causal link between protein turnover and developmental tempo through proteasomal degradation

Developmental Cell@cp-devcell.bsky.social · 3w ago

Online now: Proteasome-dependent protein degradation shapes developmental tempo in mouse and human neural progenitors #biology #science

Cis-regulatory strategies in developmental patterning - a new review written by me and @joadelas.bsky.social is out! We discuss how two distinct cis-regulatory strategies, differential accessibility and differential binding, direct cell fate, and spatial and temporal patterning during development.

We have a new lab photo. Busy times in the Delas Lab! Last month Maria and Shaun joined us to start their PhDs. Learn more about our research and our team: delaslab.com We will be recruiting another postdoc next year so have a look through our recent work and get in touch if you are interested.

Pleased to share our latest work. Extremely fun project with @jamesbriscoe.bsky.social l and @jcornwallscoones.bsky.social y.social Curious about how cis-regulatory elements encode information? Passionate about patterning (re)engineering? Please read! (🧵 by Jake below) bsky.app/profile/jcor...

Jake Cornwall-Scoones@jcornwallscoones.bsky.social · last yr.

Excited to share my latest work with @joadelas.bsky.social and @jamesbriscoe.bsky.social Predictable Engineering of Signal-Dependent Cis-Regulatory Elements www.biorxiv.org/content/10.1... 1/11

We thrilled to see our latest study led by @jeremie-subrini.bsky.social now out in @science.org 🔬 What are the specific functions of each Y-chromosome gene in fertility ? We generated and studied 13 Y-gene KO mouse models to find out! 🧬 www.science.org/doi/full/10....