✂️ Editing sequence alignments in Jalview is flexible and reversible. Move sequences ↕️, create groups 👥, insert gaps ➖, using both mouse or keyboard. Edits can also be undone! 🎥 Learn how: www.youtube.com/watch?v=FXGI...

Batches of protein sequences can be submitted to the JPred server for protein secondary structure prediction, with the option to receive a copy of the results via email. 🔗 www.youtube.com/watch?v=yLga... 🔗 www.compbio.dundee.ac.uk/jpred/help.s... 📜 academic.oup.com/nar/article/...

🎩 Sequences can be hidden in Jalview, allowing specific subsets within the alignment to be focused on and analysed. Hiding sequences improves the readability of large MSAs and the presentation of results for publication. 🔗 www.youtube.com/watch?v=9s7W... 🔗 www.jalview.org/tutorial/exe...

📺 Powering off your tech devices for the summer? Learning never stops! You can watch key bioinformatics lectures by Prof. Geoff Barton on the fundamentals of MSA analysis on your TV instead. Plus, a free 1 hour Jalview masterclass by Jalview Co-ordinator, Dr. Jim Procter. 🔗 Links in comments.

📬 Protein and nucleotide structures can be imported into Jalview, mapped on to MSA sequences and visualised in 3D. Our latest training video summarises some of the structure import options available to users. ▶️ Watch it here: www.youtube.com/watch?v=xFUu...

✂️ Sequence redundancy can create bias and slow down the analysis of alignments. With Jalview, you can quickly reduce redundancy by filtering sequences based on percentage identity. Just adjust the threshold slider to your chosen cutoff! Read more: www.jalview.org/tutorial/exe...

💾 Taking a break? Save your work in Jalview! Alignments, annotations, trees, structures, colours, views and more can be preserved in Jalview, enabling you to begin where you left off. ⬇️ Find out more. 🔗 www.youtube.com/watch?v=xT4g...

⚽ As football fever builds, there’s one competition where every nation is poised to win. 📺 Jalview’s YouTube channel has been watched 250,000+ times by scientists, students and bioinformaticians across 150+ countries. 🧬 Why not tune in too? ⬇️ Link below. 🔗 www.youtube.com/@jalviewtrai...

🏊🏼‍♂️ Dive into molecular structures this summer with Jalview’s integrated 3D viewers. Visualize thousands of protein, DNA and RNA structures with PyMOL, Chimera, ChimeraX and Jmol — whether you're an experienced bioinformatician or just getting started! ▶️ Learn more: www.youtube.com/watch?v=pbms...

🗞️ New preprint: Slivka & Slivka-bio — a lightweight framework for turning command-line tools into web services, developed by Jalview, the Dundee Resource and Genentech. 📜 www.biorxiv.org/content/10.6... ⚡Slivka-bio is set to replace JABAWS in a future release.

Explore the adverse effects of genetic mutations in 2D and 3D views by loading the coding DNA of protein sequences. 1️⃣ Jalview's protein-CDS view: www.youtube.com/watch?v=qFMJ... 2️⃣ Feature mapping: www.youtube.com/watch?v=eK6a... 3️⃣ Genomics file imports: www.youtube.com/watch?v=n_lR...

⚙️Large alignments can be tackled in Jalview by running alignment services using Slivka in Jalview 2.12 (now available via Jalview Develop). Downloading a local copy of JABAWS is another option. ⬇️ See below for links to both.

Protein secondary structure can be inferred using a number of machine learning methods. In our latest training video, we explore how two such methods — AlphaFold and JPred — can be accessed from Jalview to compare and contrast results. ▶️ Watch it here: www.youtube.com/watch?v=x7SH...

💊 Finding druggable protein domains is hard—but AlphaFold's PAE data can help. Jalview lets you import this into alignments, so it can be clustered to understand protein structure better. ➡️ PAE import: youtu.be/jowUEG47F-Q?... ➡️ Domain detection: youtu.be/pQC8LTDCbug?...

🧮 Are you making the most of Jalview’s annotation rows? These visual layers add context for interpreting biological structure & function: conservation, alignment quality, consensus, secondary structure, AlphaFold's pLDDT & PAE. ➡️ Group/user-specific annotations can also be created.

Boost your workflow with Jalview’s 'Find' function! ✅ Locate motifs sequentially or en masse ✅ Designate hits as new features ✅ Copy to other alignments ✅ Visualize rapidly using the 'Overview Window' ⏰ Save time and see the big picture. 📖 Read more: www.jalview.org/help/html/fe...

JPred predicts protein secondary structure from multiple sequence alignments—and you can access it directly from Jalview. Supported file formats include: ✅ MSF ✅ FASTA ✅ BLC Add your email to get notified when your job finishes 🪄 ▶️ Learn more in our training video: www.youtube.com/watch?v=EW6b...

Did you know Jalview can bring your alignments to life in 3D? Experience the beauty of molecular graphics with PyMol, UCSF Chimera, ChimeraX and JMol in the editor. ▶️ Watch our NEW training video for more insights: www.youtube.com/watch?v=pbms...

💡AlphaFold's pLDDT scores can be visualised in Jalview as annotation tracks at the bottom - useful when comparing regions of high confidence across predicted protein structures in alignments. ▶️ For a guided tour of AlphaFold metrics in Jalview, watch: www.youtube.com/watch?v=WVCM...

🔎 Browse extensive libraries of protein structures in Jalview using the 3D Beacons Network. Once imported, these can be colored, superimposed and viewed in 3D in conjunction with alignments. 👓 Synced views provide precision and clarity, allowing you to hone in on regions of importance.

📝 Alignments are much easier to analyse when you can read the sequences better. Jalview allows you to change alignment font size and type from its 'Format' menu. Choose 'Font' to gain access to more than 100 fonts and make your alignments pop in publications and presentations alike!

🖥️ In the right place with the wrong tech? Worry not - Jalview can be installed on MacOS, Windows and Linux- and Unix-based platforms. It can also be dowloaded via Conda and Homebrew and be run in your favourite web browser, making it an ideal choice for alignment analysis across many devices.

📈 Jalview is cited ~1,000 times/year—but how is it used? A 2024 survey found 70% of studies used Jalview for multiple sequence alignment (MSA). But, it can also be used for secondary structure and disorder prediction, conservation analyses, sequence feature mapping and 3D structure visualization.

🌍 Twelve months of hard work - endless possibilities for world science. Watch our video tribute to the Jalview community for making 2025 such an incredible year for all of us! (Sound on 🗣️) Thank you all ❤️

❄️Thank you so much to all our users and followers worldwide for making 2025 such a memorable year for us! Seasons greetings to all from the Jalview team all the way from wintry Scotland.❄️ We hope to see you in the new year! ❤️

Jalview 2.11.5.1 is here! New features include: 🎁 Enhanced display of secondary structure consensus annotation tracks 🎁 Improved visualization of phylogenetic trees and PCA plots for secondary structures 🎁 Recognition of .a3m files Download the new version at: www.jalview.org/download/

🔍Trouble viewing alignments? The Jalview overview window gives you the opportunity to spot patterns in your alignments with a single look. Read more about it at: www.jalview.org/help/html/fe...

💡Beacon of hope! Did you know Jalview allows you to access thousands of experimental and predicted protein structures programmatically through the 3D Beacons network? 🔽Find out how on our YouTube channel: www.youtube.com/watch?v=ZBDZ...

Working in Drug Discovery ? 💊 A whole host of clinically relevant features can be visualised on sequences in Jalview — allowing for pharmacologically important regions to be identified. ⬇️ Watch our training video to find out how: www.youtube.com/watch?v=nLIN...

🌍 This week, we had the pleasure of providing training to the new cohort of life sciences postgraduate students at the University of Dundee. An array of topics were covered from the basics of multiple sequence alignment to AlphaFold structure quality in Jalview. All the best for the future! ✨